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PubMed code 19627147

Compile data set for download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50017231
PNG
((4aS,9aR)-4a-Ethyl-2-phenethyl-1,2,3,4,4a,9a-hexah...)
Show SMILES CC[C@@]12CCN(CCc3ccccc3)C[C@@H]1Oc1ccc(O)cc21
Show InChI InChI=1S/C21H25NO2/c1-2-21-11-13-22(12-10-16-6-4-3-5-7-16)15-20(21)24-19-9-8-17(23)14-18(19)21/h3-9,14,20,23H,2,10-13,15H2,1H3/t20-,21-/m0/s1
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0.700n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50000092
PNG
((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1|
Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
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PubMed
2.60n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50300369
PNG
(4aS,9aR,2'S-(-)-cis-2-(2'-Hydroxy-2-phenylethyl)-4...)
Show SMILES CC[C@@]12CCN(C[C@@H](O)c3ccccc3)C[C@@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20+,21+/m1/s1
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9.30n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50017236
PNG
((4aS,9aR)-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-hexahydr...)
Show SMILES CC[C@@]12CCN(C)C[C@@H]1Oc1ccc(O)cc21
Show InChI InChI=1S/C14H19NO2/c1-3-14-6-7-15(2)9-13(14)17-12-5-4-10(16)8-11(12)14/h4-5,8,13,16H,3,6-7,9H2,1-2H3/t13-,14-/m0/s1
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16n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50300370
PNG
(4aS,9aR-(-)-cis-4a-Ethyl-1,2,3,4,4a,9a-hexahydrobe...)
Show SMILES CC[C@@]12CCNC[C@@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C13H17NO2/c1-2-13-5-6-14-8-12(13)16-11-4-3-9(15)7-10(11)13/h3-4,7,12,14-15H,2,5-6,8H2,1H3/t12-,13-/m0/s1
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48n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50017231
PNG
((4aS,9aR)-4a-Ethyl-2-phenethyl-1,2,3,4,4a,9a-hexah...)
Show SMILES CC[C@@]12CCN(CCc3ccccc3)C[C@@H]1Oc1ccc(O)cc21
Show InChI InChI=1S/C21H25NO2/c1-2-21-11-13-22(12-10-16-6-4-3-5-7-16)15-20(21)24-19-9-8-17(23)14-18(19)21/h3-9,14,20,23H,2,10-13,15H2,1H3/t20-,21-/m0/s1
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75n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50300368
PNG
(4aS,9aR,2'R-(-)-cis-2-(2'-Hydroxy-2-phenylethyl)-4...)
Show SMILES CC[C@@]12CCN(C[C@H](O)c3ccccc3)C[C@@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20-,21-/m0/s1
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80n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50017231
PNG
((4aS,9aR)-4a-Ethyl-2-phenethyl-1,2,3,4,4a,9a-hexah...)
Show SMILES CC[C@@]12CCN(CCc3ccccc3)C[C@@H]1Oc1ccc(O)cc21
Show InChI InChI=1S/C21H25NO2/c1-2-21-11-13-22(12-10-16-6-4-3-5-7-16)15-20(21)24-19-9-8-17(23)14-18(19)21/h3-9,14,20,23H,2,10-13,15H2,1H3/t20-,21-/m0/s1
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88n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50300365
PNG
(4aR,9aS-(+)-cis-4a-Ethyl-2-phenylethyl-1,2,3,4,4a,...)
Show SMILES CC[C@]12CCN(CCc3ccccc3)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO2/c1-2-21-11-13-22(12-10-16-6-4-3-5-7-16)15-20(21)24-19-9-8-17(23)14-18(19)21/h3-9,14,20,23H,2,10-13,15H2,1H3/t20-,21-/m1/s1
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200n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50300369
PNG
(4aS,9aR,2'S-(-)-cis-2-(2'-Hydroxy-2-phenylethyl)-4...)
Show SMILES CC[C@@]12CCN(C[C@@H](O)c3ccccc3)C[C@@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20+,21+/m1/s1
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413n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50300369
PNG
(4aS,9aR,2'S-(-)-cis-2-(2'-Hydroxy-2-phenylethyl)-4...)
Show SMILES CC[C@@]12CCN(C[C@@H](O)c3ccccc3)C[C@@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20+,21+/m1/s1
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443n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50017236
PNG
((4aS,9aR)-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-hexahydr...)
Show SMILES CC[C@@]12CCN(C)C[C@@H]1Oc1ccc(O)cc21
Show InChI InChI=1S/C14H19NO2/c1-3-14-6-7-15(2)9-13(14)17-12-5-4-10(16)8-11(12)14/h4-5,8,13,16H,3,6-7,9H2,1-2H3/t13-,14-/m0/s1
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450n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50300364
PNG
(4aR,9aS,2'S-(+)-cis-2-(2'-Hydroxy-2'-phenylethyl)-...)
Show SMILES CC[C@]12CCN(C[C@@H](O)c3ccccc3)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20-,21-/m1/s1
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600n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50300368
PNG
(4aS,9aR,2'R-(-)-cis-2-(2'-Hydroxy-2-phenylethyl)-4...)
Show SMILES CC[C@@]12CCN(C[C@H](O)c3ccccc3)C[C@@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20-,21-/m0/s1
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807n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50300366
PNG
(4aR,9aS-(+)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Show SMILES CC[C@]12CCN(C)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C14H19NO2/c1-3-14-6-7-15(2)9-13(14)17-12-5-4-10(16)8-11(12)14/h4-5,8,13,16H,3,6-7,9H2,1-2H3/t13-,14-/m1/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50300368
PNG
(4aS,9aR,2'R-(-)-cis-2-(2'-Hydroxy-2-phenylethyl)-4...)
Show SMILES CC[C@@]12CCN(C[C@H](O)c3ccccc3)C[C@@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20-,21-/m0/s1
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1.09E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50300366
PNG
(4aR,9aS-(+)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Show SMILES CC[C@]12CCN(C)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C14H19NO2/c1-3-14-6-7-15(2)9-13(14)17-12-5-4-10(16)8-11(12)14/h4-5,8,13,16H,3,6-7,9H2,1-2H3/t13-,14-/m1/s1
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1.33E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50300371
PNG
(4aR,9aS,2'R-(+)-cis-2-(2'-Hydroxy-2'-phenylethyl)-...)
Show SMILES CC[C@]12CCN(C[C@H](O)c3ccccc3)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20+,21+/m0/s1
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1.33E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50017236
PNG
((4aS,9aR)-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-hexahydr...)
Show SMILES CC[C@@]12CCN(C)C[C@@H]1Oc1ccc(O)cc21
Show InChI InChI=1S/C14H19NO2/c1-3-14-6-7-15(2)9-13(14)17-12-5-4-10(16)8-11(12)14/h4-5,8,13,16H,3,6-7,9H2,1-2H3/t13-,14-/m0/s1
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1.35E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50300365
PNG
(4aR,9aS-(+)-cis-4a-Ethyl-2-phenylethyl-1,2,3,4,4a,...)
Show SMILES CC[C@]12CCN(CCc3ccccc3)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO2/c1-2-21-11-13-22(12-10-16-6-4-3-5-7-16)15-20(21)24-19-9-8-17(23)14-18(19)21/h3-9,14,20,23H,2,10-13,15H2,1H3/t20-,21-/m1/s1
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2.33E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50300364
PNG
(4aR,9aS,2'S-(+)-cis-2-(2'-Hydroxy-2'-phenylethyl)-...)
Show SMILES CC[C@]12CCN(C[C@@H](O)c3ccccc3)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20-,21-/m1/s1
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2.49E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50300365
PNG
(4aR,9aS-(+)-cis-4a-Ethyl-2-phenylethyl-1,2,3,4,4a,...)
Show SMILES CC[C@]12CCN(CCc3ccccc3)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO2/c1-2-21-11-13-22(12-10-16-6-4-3-5-7-16)15-20(21)24-19-9-8-17(23)14-18(19)21/h3-9,14,20,23H,2,10-13,15H2,1H3/t20-,21-/m1/s1
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2.69E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50300371
PNG
(4aR,9aS,2'R-(+)-cis-2-(2'-Hydroxy-2'-phenylethyl)-...)
Show SMILES CC[C@]12CCN(C[C@H](O)c3ccccc3)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20+,21+/m0/s1
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3.10E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50300367
PNG
(4aR,9aS-(+)-cis-4a-Ethyl-1,2,3,4,4a,9a-hexahydrobe...)
Show SMILES CC[C@]12CCNC[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C13H17NO2/c1-2-13-5-6-14-8-12(13)16-11-4-3-9(15)7-10(11)13/h3-4,7,12,14-15H,2,5-6,8H2,1H3/t12-,13-/m1/s1
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3.50E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50300366
PNG
(4aR,9aS-(+)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Show SMILES CC[C@]12CCN(C)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C14H19NO2/c1-3-14-6-7-15(2)9-13(14)17-12-5-4-10(16)8-11(12)14/h4-5,8,13,16H,3,6-7,9H2,1-2H3/t13-,14-/m1/s1
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4.27E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50300364
PNG
(4aR,9aS,2'S-(+)-cis-2-(2'-Hydroxy-2'-phenylethyl)-...)
Show SMILES CC[C@]12CCN(C[C@@H](O)c3ccccc3)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20-,21-/m1/s1
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5.87E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50300371
PNG
(4aR,9aS,2'R-(+)-cis-2-(2'-Hydroxy-2'-phenylethyl)-...)
Show SMILES CC[C@]12CCN(C[C@H](O)c3ccccc3)C[C@H]1Oc1ccc(O)cc21 |r|
Show InChI InChI=1S/C21H25NO3/c1-2-21-10-11-22(13-18(24)15-6-4-3-5-7-15)14-20(21)25-19-9-8-16(23)12-17(19)21/h3-9,12,18,20,23-24H,2,10-11,13-14H2,1H3/t18-,20+,21+/m0/s1
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9.50E+3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholi

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells


J Med Chem 52: 7570-9 (2009)


Article DOI: 10.1021/jm9004225
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%