Affinity Data by PubMed id=19666228

PubMed code 19666228

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50304140 (9-[2-(1-Phosphonopropan-2-yloxy)ethyl]guanine \| CH...) Show SMILES CC(CP(O)(O)=O)OCCn1cnc2c1nc(N)[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human recombinant HGPRT expressed in Escherichia coli by spectrophotometric assay				Bioorg Med Chem 17: 6218-32 (2009) Article DOI: 10.1016/j.bmc.2009.07.044 BindingDB Entry DOI: 10.7270/Q23778TP
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50304141 (9-[2-(1-Phosphonobutan-2-yloxy)ethyl]guanine \| CHE...) Show SMILES CCC(CP(O)(O)=O)OCCn1cnc2c1nc(N)[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human recombinant HGPRT expressed in Escherichia coli by spectrophotometric assay				Bioorg Med Chem 17: 6218-32 (2009) Article DOI: 10.1016/j.bmc.2009.07.044 BindingDB Entry DOI: 10.7270/Q23778TP
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50304138 (9-[2-(1-Phosphonopropan-2-yloxy)ethyl]hypoxanthine...) Show SMILES CC(CP(O)(O)=O)OCCn1cnc2c1nc[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human recombinant HGPRT expressed in Escherichia coli by spectrophotometric assay				Bioorg Med Chem 17: 6218-32 (2009) Article DOI: 10.1016/j.bmc.2009.07.044 BindingDB Entry DOI: 10.7270/Q23778TP
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50304139 (9-[2-(1-Phosphonobutan-2-yloxy)ethyl]hypoxanthine ...) Show SMILES CCC(CP(O)(O)=O)OCCn1cnc2c1nc[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human recombinant HGPRT expressed in Escherichia coli by spectrophotometric assay				Bioorg Med Chem 17: 6218-32 (2009) Article DOI: 10.1016/j.bmc.2009.07.044 BindingDB Entry DOI: 10.7270/Q23778TP
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%