Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31629 (Aminopyridine N-oxide, 55) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31630 (Aminopyridine N-oxide, 56) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31621 (Aminopyridine N-oxide, 47) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31632 (Aminopyridine N-oxide, 58) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31624 (Aminopyridine N-oxide, 50) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31622 (Aminopyridine N-oxide, 48) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31623 (Aminopyridine N-oxide, 49) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31634 (Aminopyridine N-oxide, 60) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31619 (Aminopyridine N-oxide, 45) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31618 (Aminopyridine N-oxide, 44) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31612 (Aminopyridine N-oxide, 38) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31626 (Aminopyridine N-oxide, 52) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31625 (Aminopyridine N-oxide, 51) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31628 (Aminopyridine N-oxide, 54) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31615 (Aminopyridine N-oxide, 41) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31633 (Aminopyridine N-oxide, 59) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31635 (Aminopyridine N-oxide, 61) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31627 (Aminopyridine N-oxide, 53) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 126 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31613 (Aminopyridine N-oxide, 39) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 149 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31609 (Aminopyridine N-oxide, 35) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 174 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31620 (Aminopyridine N-oxide, 46) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 208 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31616 (Aminopyridine N-oxide, 42) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 228 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31610 (Aminopyridine N-oxide, 36) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 411 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31631 (Aminopyridine N-oxide, 57) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 491 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31617 (Aminopyridine N-oxide, 43) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 802 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31608 (Aminopyridine N-oxide, 34) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 967 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31614 (Aminopyridine N-oxide, 40) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM31611 (Aminopyridine N-oxide, 37) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.53E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall Research Center | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate... | J Med Chem 52: 5531-45 (2009) Article DOI: 10.1021/jm9008604 BindingDB Entry DOI: 10.7270/Q25719B5 | |||||||||||
More data for this Ligand-Target Pair |