Affinity Data by PubMed id=19715279

PubMed code 19715279

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50010704 (CHEMBL216640 \| Dyn A(1-11)-NH2 \| Dynorphin A analo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297345 ((5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50010704 (CHEMBL216640 \| Dyn A(1-11)-NH2 \| Dynorphin A analo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50297345 ((5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297347 ((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50010704 (CHEMBL216640 \| Dyn A(1-11)-NH2 \| Dynorphin A analo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50297345 ((5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297347 ((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50297347 ((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297343 ((5S,8S,13S,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50297347 ((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50297347 ((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50297343 ((5S,8S,13S,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	763	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50297347 ((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50297343 ((5S,8S,13S,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297345 ((5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297343 ((5S,8S,13S,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50010704 (CHEMBL216640 \| Dyn A(1-11)-NH2 \| Dynorphin A analo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.390	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297347 ((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.30	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297347 ((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%