Affinity Data by PubMed id=19719236

PubMed code 19719236

Found 23 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295043 ((E)-12-Nitrooctadec-12-enoic Acid \| CHEMBL549351) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295044 ((E)-13-Nitrooctadec-12-enoic Acid \| CHEMBL540732) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295045 ((9Z,12E)-12-nitrooctadeca-9,12-dienoic acid \| CHEM...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295046 ((E)-10-Nitrohexadec-9-enoic Acid \| CHEMBL564368) Show SMILES CCCCCC\C(=C/CCCCCCCC(O)=O)[N+]([O-])=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295047 ((E)-9-Nitrohexadec-9-enoicAcid \| CHEMBL560513) Show SMILES CCCCCC\C=C(/CCCCCCCC(O)=O)[N+]([O-])=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295048 ((E)-9-nitrooctadec-9-enoic acid \| CHEMBL550762 \| N...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295044 ((E)-13-Nitrooctadec-12-enoic Acid \| CHEMBL540732) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295043 ((E)-12-Nitrooctadec-12-enoic Acid \| CHEMBL549351) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295049 ((E)-10-nitrooctadec-9-enoic acid \| CHEMBL561371) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295050 ((E)-5-Nitrooctadec-5-enoic Acid \| CHEMBL561776) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295051 ((E)-6-Nitrooctadec-5-enoic Acid \| CHEMBL569372) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295045 ((9Z,12E)-12-nitrooctadeca-9,12-dienoic acid \| CHEM...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295047 ((E)-9-Nitrohexadec-9-enoicAcid \| CHEMBL560513) Show SMILES CCCCCC\C=C(/CCCCCCCC(O)=O)[N+]([O-])=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295050 ((E)-5-Nitrooctadec-5-enoic Acid \| CHEMBL561776) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295046 ((E)-10-Nitrohexadec-9-enoic Acid \| CHEMBL564368) Show SMILES CCCCCC\C(=C/CCCCCCCC(O)=O)[N+]([O-])=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295051 ((E)-6-Nitrooctadec-5-enoic Acid \| CHEMBL569372) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295049 ((E)-10-nitrooctadec-9-enoic acid \| CHEMBL561371) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295048 ((E)-9-nitrooctadec-9-enoic acid \| CHEMBL550762 \| N...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295045 ((9Z,12E)-12-nitrooctadeca-9,12-dienoic acid \| CHEM...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Activation of PPARgamma				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295044 ((E)-13-Nitrooctadec-12-enoic Acid \| CHEMBL540732) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Activation of PPARgamma				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295045 ((9Z,12E)-12-nitrooctadeca-9,12-dienoic acid \| CHEM...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Activation of human PPARgamma-dependent transcription expressed in human MCF7 cells assessed as induction of PPRE-reporter gene expression after 24 h...				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%