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PubMed code 19726200

Compile data set for download or QSAR
Found 37 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycine receptor subunit alpha-1


(RAT)		BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 1.07n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycine

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50304334
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1
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n/an/a 10.2n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 11.5n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 3A


(RAT)		BDBM50304334
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1
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n/an/a 18n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrain

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 3A


(RAT)		BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 25n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrain

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 3A


(RAT)		BDBM50304333
PNG
(3alpha-(2'-Indolecarbonyloxy)-nortropane | CHEMBL5...)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1cc2ccccc2[nH]1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C16H18N2O2/c19-16(15-7-10-3-1-2-4-14(10)18-15)20-13-8-11-5-6-12(9-13)17-11/h1-4,7,11-13,17-18H,5-6,8-9H2/t11-,12-/m1/s1
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n/an/a 32n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrain

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415201
PNG
(CHEMBL611364)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccc[nH]1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C13H18N2O2/c1-15-9-4-5-10(15)8-11(7-9)17-13(16)12-3-2-6-14-12/h2-3,6,9-11,14H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 33.9n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 33.9n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415204
PNG
(CHEMBL596443)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1cccs1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C12H15NO2S/c14-12(11-2-1-5-16-11)15-10-6-8-3-4-9(7-10)13-8/h1-2,5,8-10,13H,3-4,6-7H2/t8-,9-/m1/s1
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n/an/a 41.7n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415205
PNG
(CHEMBL595797)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccco1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C13H17NO3/c1-14-9-4-5-10(14)8-11(7-9)17-13(15)12-3-2-6-16-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 50.1n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415208
PNG
(CHEMBL608418)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccnc1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C14H18N2O2/c1-16-11-4-5-12(16)8-13(7-11)18-14(17)10-3-2-6-15-9-10/h2-3,6,9,11-13H,4-5,7-8H2,1H3/t11-,12-/m1/s1
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n/an/a 58.9n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415210
PNG
(CHEMBL608417)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2[nH]1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C17H20N2O2/c1-19-12-6-7-13(19)10-14(9-12)21-17(20)16-8-11-4-2-3-5-15(11)18-16/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 60.3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 70.8n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycine

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415211
PNG
(CHEMBL595791)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3/t14-,15-/m1/s1
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n/an/a 72.4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415206
PNG
(CHEMBL596257)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1ccco1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C12H15NO3/c14-12(11-2-1-5-15-11)16-10-6-8-3-4-9(7-10)13-8/h1-2,5,8-10,13H,3-4,6-7H2/t8-,9-/m1/s1
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n/an/a 79.4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415203
PNG
(CHEMBL595116)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccs1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C13H17NO2S/c1-14-9-4-5-10(14)8-11(7-9)16-13(15)12-3-2-6-17-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 89.1n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415209
PNG
(CHEMBL596237)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1cccnc1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C13H16N2O2/c16-13(9-2-1-5-14-8-9)17-12-6-10-3-4-11(7-12)15-10/h1-2,5,8,10-12,15H,3-4,6-7H2/t10-,11-/m1/s1
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n/an/a 100n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 126n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415202
PNG
(CHEMBL611365)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1ccc[nH]1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C12H16N2O2/c15-12(11-2-1-5-13-11)16-10-6-8-3-4-9(7-10)14-8/h1-2,5,8-10,13-14H,3-4,6-7H2/t8-,9-/m1/s1
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n/an/a 129n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 135n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycine

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415200
PNG
(CHEMBL610170)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1cnc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C17H18N2O2/c20-17(21-15-8-13-5-6-14(9-15)19-13)12-7-11-3-1-2-4-16(11)18-10-12/h1-4,7,10,13-15,19H,5-6,8-9H2/t13-,14-/m1/s1
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n/an/a 166n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50304333
PNG
(3alpha-(2'-Indolecarbonyloxy)-nortropane | CHEMBL5...)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1cc2ccccc2[nH]1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C16H18N2O2/c19-16(15-7-10-3-1-2-4-14(10)18-15)20-13-8-11-5-6-12(9-13)17-11/h1-4,7,11-13,17-18H,5-6,8-9H2/t11-,12-/m1/s1
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n/an/a 234n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50304334
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1
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n/an/a 1.58E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415203
PNG
(CHEMBL595116)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccs1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C13H17NO2S/c1-14-9-4-5-10(14)8-11(7-9)16-13(15)12-3-2-6-17-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 1.91E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415211
PNG
(CHEMBL595791)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3/t14-,15-/m1/s1
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n/an/a 1.91E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50304334
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1
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n/an/a 2.40E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415203
PNG
(CHEMBL595116)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccs1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C13H17NO2S/c1-14-9-4-5-10(14)8-11(7-9)16-13(15)12-3-2-6-17-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 4.27E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415208
PNG
(CHEMBL608418)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccnc1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C14H18N2O2/c1-16-11-4-5-12(16)8-13(7-11)18-14(17)10-3-2-6-15-9-10/h2-3,6,9,11-13H,4-5,7-8H2,1H3/t11-,12-/m1/s1
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n/an/a 4.27E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415210
PNG
(CHEMBL608417)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2[nH]1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C17H20N2O2/c1-19-12-6-7-13(19)10-14(9-12)21-17(20)16-8-11-4-2-3-5-15(11)18-16/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 4.68E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415211
PNG
(CHEMBL595791)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3/t14-,15-/m1/s1
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n/an/a 5.50E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415205
PNG
(CHEMBL595797)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccco1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C13H17NO3/c1-14-9-4-5-10(14)8-11(7-9)17-13(15)12-3-2-6-16-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 5.62E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415207
PNG
(CHEMBL594193)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccn1C |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C14H20N2O2/c1-15-7-3-4-13(15)14(17)18-12-8-10-5-6-11(9-12)16(10)2/h3-4,7,10-12H,5-6,8-9H2,1-2H3/t10-,11-/m1/s1
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n/an/a 7.59E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415210
PNG
(CHEMBL608417)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2[nH]1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C17H20N2O2/c1-19-12-6-7-13(19)10-14(9-12)21-17(20)16-8-11-4-2-3-5-15(11)18-16/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 7.94E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415205
PNG
(CHEMBL595797)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccco1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C13H17NO3/c1-14-9-4-5-10(14)8-11(7-9)17-13(15)12-3-2-6-16-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415201
PNG
(CHEMBL611364)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccc[nH]1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C13H18N2O2/c1-15-9-4-5-10(15)8-11(7-9)17-13(16)12-3-2-6-14-12/h2-3,6,9-11,14H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 1.12E+4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415201
PNG
(CHEMBL611364)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccc[nH]1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C13H18N2O2/c1-15-9-4-5-10(15)8-11(7-9)17-13(16)12-3-2-6-14-12/h2-3,6,9-11,14H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 2.09E+4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
Glycine receptor subunit alpha-1


(RAT)		BDBM50415208
PNG
(CHEMBL608418)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccnc1 |r,THB:9:7:1:3.4|
Show InChI InChI=1S/C14H18N2O2/c1-16-11-4-5-12(16)8-13(7-11)18-14(17)10-3-2-6-15-9-10/h2-3,6,9,11-13H,4-5,7-8H2,1H3/t11-,12-/m1/s1
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n/an/a 2.29E+4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry

Bioorg Med Chem 17: 6872-8 (2009)


Article DOI: 10.1016/j.bmc.2009.08.029
BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%