BindingDB logo
myBDB logout

PubMed code 19800790

Compile data set for download or QSAR
Found 62 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299393
PNG
(4-((1-benzylpiperidin-4-yl)(3-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)24-13-15-26(16-14-24)34(28-12-8-11-25(21-28)29(31)35)27-17-19-32(20-18-27)22-23-9-6-5-7-10-23/h5-16,21,27H,3-4,17-20,22H2,1-2H3,(H2,31,35)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
0.290n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299390
PNG
(CHEMBL574640 | Methyl 3-((1-benzylpiperidin-4-yl)(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NC(=O)OC)c1
Show InChI InChI=1S/C31H38N4O3/c1-4-34(5-2)30(36)25-14-16-27(17-15-25)35(29-13-9-12-26(22-29)32-31(37)38-3)28-18-20-33(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3,(H,32,37)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.410n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299385
PNG
(4-((1-benzylpiperidin-4-yl)(3-hydroxyphenyl)amino)...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(O)c1
Show InChI InChI=1S/C29H35N3O2/c1-3-31(4-2)29(34)24-13-15-25(16-14-24)32(27-11-8-12-28(33)21-27)26-17-19-30(20-18-26)22-23-9-6-5-7-10-23/h5-16,21,26,33H,3-4,17-20,22H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
0.420n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299389
PNG
(4-((1-benzylpiperidin-4-yl)(3-(methylsulfonamido)p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NS(C)(=O)=O)c1
Show InChI InChI=1S/C30H38N4O3S/c1-4-33(5-2)30(35)25-14-16-27(17-15-25)34(29-13-9-12-26(22-29)31-38(3,36)37)28-18-20-32(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28,31H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.40n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299382
PNG
(4-((3-acetylphenyl)(1-benzylpiperidin-4-yl)amino)-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(C)=O
Show InChI InChI=1S/C31H37N3O2/c1-4-33(5-2)31(36)26-14-16-28(17-15-26)34(30-13-9-12-27(22-30)24(3)35)29-18-20-32(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,29H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.70n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299388
PNG
(4-((3-acetamidophenyl)(1-benzylpiperidin-4-yl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NC(C)=O)c1
Show InChI InChI=1S/C31H38N4O2/c1-4-34(5-2)31(37)26-14-16-28(17-15-26)35(30-13-9-12-27(22-30)32-24(3)36)29-18-20-33(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,29H,4-5,18-21,23H2,1-3H3,(H,32,36)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.80n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299391
PNG
(4-((3-aminophenyl)(1-benzylpiperidin-4-yl)amino)-N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(N)c1
Show InChI InChI=1S/C29H36N4O/c1-3-32(4-2)29(34)24-13-15-26(16-14-24)33(28-12-8-11-25(30)21-28)27-17-19-31(20-18-27)22-23-9-6-5-7-10-23/h5-16,21,27H,3-4,17-20,22,30H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299384
PNG
(4-((1-benzylpiperidin-4-yl)(3-formylphenyl)amino)-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(C=O)c1
Show InChI InChI=1S/C30H35N3O2/c1-3-32(4-2)30(35)26-13-15-27(16-14-26)33(29-12-8-11-25(21-29)23-34)28-17-19-31(20-18-28)22-24-9-6-5-7-10-24/h5-16,21,23,28H,3-4,17-20,22H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
3.40n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299396
PNG
(4-((1-benzylpiperidin-4-yl)(3-(hydroxymethyl)pheny...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CO)c1
Show InChI InChI=1S/C30H37N3O2/c1-3-32(4-2)30(35)26-13-15-27(16-14-26)33(29-12-8-11-25(21-29)23-34)28-17-19-31(20-18-28)22-24-9-6-5-7-10-24/h5-16,21,28,34H,3-4,17-20,22-23H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
12n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299392
PNG
(4-((1-benzylpiperidin-4-yl)(3-(methylcarbamoyl)phe...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(=O)NC
Show InChI InChI=1S/C31H38N4O2/c1-4-34(5-2)31(37)25-14-16-27(17-15-25)35(29-13-9-12-26(22-29)30(36)32-3)28-18-20-33(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3,(H,32,36)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
19n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299386
PNG
(4-((1-benzylpiperidin-4-yl)(4-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)25-12-16-27(17-13-25)34(26-14-10-24(11-15-26)29(31)35)28-18-20-32(21-19-28)22-23-8-6-5-7-9-23/h5-17,28H,3-4,18-22H2,1-2H3,(H2,31,35)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
32n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299395
PNG
(4-((1-benzylpiperidin-4-yl)(3-((dimethylamino)meth...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CN(C)C)c1
Show InChI InChI=1S/C32H42N4O/c1-5-35(6-2)32(37)28-15-17-29(18-16-28)36(31-14-10-13-27(23-31)24-33(3)4)30-19-21-34(22-20-30)25-26-11-8-7-9-12-26/h7-18,23,30H,5-6,19-22,24-25H2,1-4H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
34n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299387
PNG
(4-((1-benzylpiperidin-4-yl)(2-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1ccccc1C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)24-14-16-25(17-15-24)34(28-13-9-8-12-27(28)29(31)35)26-18-20-32(21-19-26)22-23-10-6-5-7-11-23/h5-17,26H,3-4,18-22H2,1-2H3,(H2,31,35)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
38n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299394
PNG
(CHEMBL575926 | Methyl 3-((1-benzylpiperidin-4-yl)(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(=O)OC
Show InChI InChI=1S/C31H37N3O3/c1-4-33(5-2)30(35)25-14-16-27(17-15-25)34(29-13-9-12-26(22-29)31(36)37-3)28-18-20-32(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
60n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299390
PNG
(CHEMBL574640 | Methyl 3-((1-benzylpiperidin-4-yl)(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NC(=O)OC)c1
Show InChI InChI=1S/C31H38N4O3/c1-4-34(5-2)30(36)25-14-16-27(17-15-25)35(29-13-9-12-26(22-29)32-31(37)38-3)28-18-20-33(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3,(H,32,37)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
75n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299383
PNG
(4-((1-benzylpiperidin-4-yl)(3-(1-hydroxyethyl)phen...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(C)O
Show InChI InChI=1S/C31H39N3O2/c1-4-33(5-2)31(36)26-14-16-28(17-15-26)34(30-13-9-12-27(22-30)24(3)35)29-18-20-32(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,24,29,35H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
81n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299385
PNG
(4-((1-benzylpiperidin-4-yl)(3-hydroxyphenyl)amino)...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(O)c1
Show InChI InChI=1S/C29H35N3O2/c1-3-31(4-2)29(34)24-13-15-25(16-14-24)32(27-11-8-12-28(33)21-27)26-17-19-30(20-18-26)22-23-9-6-5-7-10-23/h5-16,21,26,33H,3-4,17-20,22H2,1-2H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
88n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299397
PNG
(3-((1-benzylpiperidin-4-yl)(4-(diethylcarbamoyl)ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(=O)N(C)C
Show InChI InChI=1S/C32H40N4O2/c1-5-35(6-2)32(38)26-15-17-28(18-16-26)36(30-14-10-13-27(23-30)31(37)33(3)4)29-19-21-34(22-20-29)24-25-11-8-7-9-12-25/h7-18,23,29H,5-6,19-22,24H2,1-4H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
110n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299393
PNG
(4-((1-benzylpiperidin-4-yl)(3-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)24-13-15-26(16-14-24)34(28-12-8-11-25(21-28)29(31)35)27-17-19-32(20-18-27)22-23-9-6-5-7-10-23/h5-16,21,27H,3-4,17-20,22H2,1-2H3,(H2,31,35)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
282n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299399
PNG
(4-((1-benzylpiperidin-4-yl)(3-((methylamino)methyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CNC)c1
Show InChI InChI=1S/C31H40N4O/c1-4-34(5-2)31(36)27-14-16-28(17-15-27)35(30-13-9-12-26(22-30)23-32-3)29-18-20-33(21-19-29)24-25-10-7-6-8-11-25/h6-17,22,29,32H,4-5,18-21,23-24H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
435n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299381
PNG
(4-((3-(aminomethyl)phenyl)(1-benzylpiperidin-4-yl)...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CN)c1
Show InChI InChI=1S/C30H38N4O/c1-3-33(4-2)30(35)26-13-15-27(16-14-26)34(29-12-8-11-25(21-29)22-31)28-17-19-32(20-18-28)23-24-9-6-5-7-10-24/h5-16,21,28H,3-4,17-20,22-23,31H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
447n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299389
PNG
(4-((1-benzylpiperidin-4-yl)(3-(methylsulfonamido)p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NS(C)(=O)=O)c1
Show InChI InChI=1S/C30H38N4O3S/c1-4-33(5-2)30(35)25-14-16-27(17-15-25)34(29-13-9-12-26(22-29)31-38(3,36)37)28-18-20-32(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28,31H,4-5,18-21,23H2,1-3H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
462n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299386
PNG
(4-((1-benzylpiperidin-4-yl)(4-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)25-12-16-27(17-13-25)34(26-14-10-24(11-15-26)29(31)35)28-18-20-32(21-19-28)22-23-8-6-5-7-9-23/h5-17,28H,3-4,18-22H2,1-2H3,(H2,31,35)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
486n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299390
PNG
(CHEMBL574640 | Methyl 3-((1-benzylpiperidin-4-yl)(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NC(=O)OC)c1
Show InChI InChI=1S/C31H38N4O3/c1-4-34(5-2)30(36)25-14-16-27(17-15-25)35(29-13-9-12-26(22-29)32-31(37)38-3)28-18-20-33(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3,(H,32,37)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
576n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299393
PNG
(4-((1-benzylpiperidin-4-yl)(3-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)24-13-15-26(16-14-24)34(28-12-8-11-25(21-28)29(31)35)27-17-19-32(20-18-27)22-23-9-6-5-7-10-23/h5-16,21,27H,3-4,17-20,22H2,1-2H3,(H2,31,35)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
725n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299385
PNG
(4-((1-benzylpiperidin-4-yl)(3-hydroxyphenyl)amino)...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(O)c1
Show InChI InChI=1S/C29H35N3O2/c1-3-31(4-2)29(34)24-13-15-25(16-14-24)32(27-11-8-12-28(33)21-27)26-17-19-30(20-18-26)22-23-9-6-5-7-10-23/h5-16,21,26,33H,3-4,17-20,22H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
744n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299381
PNG
(4-((3-(aminomethyl)phenyl)(1-benzylpiperidin-4-yl)...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CN)c1
Show InChI InChI=1S/C30H38N4O/c1-3-33(4-2)30(35)26-13-15-27(16-14-26)34(29-12-8-11-25(21-29)22-31)28-17-19-32(20-18-28)23-24-9-6-5-7-10-24/h5-16,21,28H,3-4,17-20,22-23,31H2,1-2H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
831n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299388
PNG
(4-((3-acetamidophenyl)(1-benzylpiperidin-4-yl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NC(C)=O)c1
Show InChI InChI=1S/C31H38N4O2/c1-4-34(5-2)31(37)26-14-16-28(17-15-26)35(30-13-9-12-27(22-30)32-24(3)36)29-18-20-33(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,29H,4-5,18-21,23H2,1-3H3,(H,32,36)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.02E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299384
PNG
(4-((1-benzylpiperidin-4-yl)(3-formylphenyl)amino)-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(C=O)c1
Show InChI InChI=1S/C30H35N3O2/c1-3-32(4-2)30(35)26-13-15-27(16-14-26)33(29-12-8-11-25(21-29)23-34)28-17-19-31(20-18-28)22-24-9-6-5-7-10-24/h5-16,21,23,28H,3-4,17-20,22H2,1-2H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.19E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299398
PNG
(3-((1-benzylpiperidin-4-yl)(4-(diethylcarbamoyl)ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(O)=O
Show InChI InChI=1S/C30H35N3O3/c1-3-32(4-2)29(34)24-13-15-26(16-14-24)33(28-12-8-11-25(21-28)30(35)36)27-17-19-31(20-18-27)22-23-9-6-5-7-10-23/h5-16,21,27H,3-4,17-20,22H2,1-2H3,(H,35,36)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.37E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299382
PNG
(4-((3-acetylphenyl)(1-benzylpiperidin-4-yl)amino)-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(C)=O
Show InChI InChI=1S/C31H37N3O2/c1-4-33(5-2)31(36)26-14-16-28(17-15-26)34(30-13-9-12-27(22-30)24(3)35)29-18-20-32(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,29H,4-5,18-21,23H2,1-3H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.54E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299395
PNG
(4-((1-benzylpiperidin-4-yl)(3-((dimethylamino)meth...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CN(C)C)c1
Show InChI InChI=1S/C32H42N4O/c1-5-35(6-2)32(37)28-15-17-29(18-16-28)36(31-14-10-13-27(23-31)24-33(3)4)30-19-21-34(22-20-30)25-26-11-8-7-9-12-26/h7-18,23,30H,5-6,19-22,24-25H2,1-4H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.75E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299391
PNG
(4-((3-aminophenyl)(1-benzylpiperidin-4-yl)amino)-N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(N)c1
Show InChI InChI=1S/C29H36N4O/c1-3-32(4-2)29(34)24-13-15-26(16-14-24)33(28-12-8-11-25(30)21-28)27-17-19-31(20-18-27)22-23-9-6-5-7-10-23/h5-16,21,27H,3-4,17-20,22,30H2,1-2H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.88E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299381
PNG
(4-((3-(aminomethyl)phenyl)(1-benzylpiperidin-4-yl)...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CN)c1
Show InChI InChI=1S/C30H38N4O/c1-3-33(4-2)30(35)26-13-15-27(16-14-26)34(29-12-8-11-25(21-29)22-31)28-17-19-32(20-18-28)23-24-9-6-5-7-10-24/h5-16,21,28H,3-4,17-20,22-23,31H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.93E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299389
PNG
(4-((1-benzylpiperidin-4-yl)(3-(methylsulfonamido)p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NS(C)(=O)=O)c1
Show InChI InChI=1S/C30H38N4O3S/c1-4-33(5-2)30(35)25-14-16-27(17-15-25)34(29-13-9-12-26(22-29)31-38(3,36)37)28-18-20-32(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28,31H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.56E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299383
PNG
(4-((1-benzylpiperidin-4-yl)(3-(1-hydroxyethyl)phen...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(C)O
Show InChI InChI=1S/C31H39N3O2/c1-4-33(5-2)31(36)26-14-16-28(17-15-26)34(30-13-9-12-27(22-30)24(3)35)29-18-20-32(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,24,29,35H,4-5,18-21,23H2,1-3H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.75E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299396
PNG
(4-((1-benzylpiperidin-4-yl)(3-(hydroxymethyl)pheny...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CO)c1
Show InChI InChI=1S/C30H37N3O2/c1-3-32(4-2)30(35)26-13-15-27(16-14-26)33(29-12-8-11-25(21-29)23-34)28-17-19-31(20-18-28)22-24-9-6-5-7-10-24/h5-16,21,28,34H,3-4,17-20,22-23H2,1-2H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.81E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299395
PNG
(4-((1-benzylpiperidin-4-yl)(3-((dimethylamino)meth...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CN(C)C)c1
Show InChI InChI=1S/C32H42N4O/c1-5-35(6-2)32(37)28-15-17-29(18-16-28)36(31-14-10-13-27(23-31)24-33(3)4)30-19-21-34(22-20-30)25-26-11-8-7-9-12-26/h7-18,23,30H,5-6,19-22,24-25H2,1-4H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.16E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299391
PNG
(4-((3-aminophenyl)(1-benzylpiperidin-4-yl)amino)-N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(N)c1
Show InChI InChI=1S/C29H36N4O/c1-3-32(4-2)29(34)24-13-15-26(16-14-24)33(28-12-8-11-25(30)21-28)27-17-19-31(20-18-27)22-23-9-6-5-7-10-23/h5-16,21,27H,3-4,17-20,22,30H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.25E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299382
PNG
(4-((3-acetylphenyl)(1-benzylpiperidin-4-yl)amino)-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(C)=O
Show InChI InChI=1S/C31H37N3O2/c1-4-33(5-2)31(36)26-14-16-28(17-15-26)34(30-13-9-12-27(22-30)24(3)35)29-18-20-32(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,29H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.54E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299392
PNG
(4-((1-benzylpiperidin-4-yl)(3-(methylcarbamoyl)phe...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(=O)NC
Show InChI InChI=1S/C31H38N4O2/c1-4-34(5-2)31(37)25-14-16-27(17-15-25)35(29-13-9-12-26(22-29)30(36)32-3)28-18-20-33(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3,(H,32,36)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.71E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299383
PNG
(4-((1-benzylpiperidin-4-yl)(3-(1-hydroxyethyl)phen...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(C)O
Show InChI InChI=1S/C31H39N3O2/c1-4-33(5-2)31(36)26-14-16-28(17-15-26)34(30-13-9-12-27(22-30)24(3)35)29-18-20-32(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,24,29,35H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.74E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299384
PNG
(4-((1-benzylpiperidin-4-yl)(3-formylphenyl)amino)-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(C=O)c1
Show InChI InChI=1S/C30H35N3O2/c1-3-32(4-2)30(35)26-13-15-27(16-14-26)33(29-12-8-11-25(21-29)23-34)28-17-19-31(20-18-28)22-24-9-6-5-7-10-24/h5-16,21,23,28H,3-4,17-20,22H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
4.80E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299387
PNG
(4-((1-benzylpiperidin-4-yl)(2-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1ccccc1C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)24-14-16-25(17-15-24)34(28-13-9-8-12-27(28)29(31)35)26-18-20-32(21-19-26)22-23-10-6-5-7-11-23/h5-17,26H,3-4,18-22H2,1-2H3,(H2,31,35)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5.04E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299394
PNG
(CHEMBL575926 | Methyl 3-((1-benzylpiperidin-4-yl)(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(=O)OC
Show InChI InChI=1S/C31H37N3O3/c1-4-33(5-2)30(35)25-14-16-27(17-15-25)34(29-13-9-12-26(22-29)31(36)37-3)28-18-20-32(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5.54E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299386
PNG
(4-((1-benzylpiperidin-4-yl)(4-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)25-12-16-27(17-13-25)34(26-14-10-24(11-15-26)29(31)35)28-18-20-32(21-19-28)22-23-8-6-5-7-9-23/h5-17,28H,3-4,18-22H2,1-2H3,(H2,31,35)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
6.18E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299396
PNG
(4-((1-benzylpiperidin-4-yl)(3-(hydroxymethyl)pheny...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CO)c1
Show InChI InChI=1S/C30H37N3O2/c1-3-32(4-2)30(35)26-13-15-27(16-14-26)33(29-12-8-11-25(21-29)23-34)28-17-19-31(20-18-28)22-24-9-6-5-7-10-24/h5-16,21,28,34H,3-4,17-20,22-23H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
6.67E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50299394
PNG
(CHEMBL575926 | Methyl 3-((1-benzylpiperidin-4-yl)(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(=O)OC
Show InChI InChI=1S/C31H37N3O3/c1-4-33(5-2)30(35)25-14-16-27(17-15-25)34(29-13-9-12-26(22-29)31(36)37-3)28-18-20-32(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7.10E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]FK33824 from human cloned mu opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299387
PNG
(4-((1-benzylpiperidin-4-yl)(2-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1ccccc1C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)24-14-16-25(17-15-24)34(28-13-9-8-12-27(28)29(31)35)26-18-20-32(21-19-26)22-23-10-6-5-7-11-23/h5-17,26H,3-4,18-22H2,1-2H3,(H2,31,35)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299388
PNG
(4-((3-acetamidophenyl)(1-benzylpiperidin-4-yl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NC(C)=O)c1
Show InChI InChI=1S/C31H38N4O2/c1-4-34(5-2)31(37)26-14-16-28(17-15-26)35(30-13-9-12-27(22-30)32-24(3)36)29-18-20-33(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,29H,4-5,18-21,23H2,1-3H3,(H,32,36)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50299392
PNG
(4-((1-benzylpiperidin-4-yl)(3-(methylcarbamoyl)phe...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(=O)NC
Show InChI InChI=1S/C31H38N4O2/c1-4-34(5-2)31(37)25-14-16-27(17-15-25)35(29-13-9-12-26(22-29)30(36)32-3)28-18-20-33(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3,(H,32,36)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299390
PNG
(CHEMBL574640 | Methyl 3-((1-benzylpiperidin-4-yl)(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NC(=O)OC)c1
Show InChI InChI=1S/C31H38N4O3/c1-4-34(5-2)30(36)25-14-16-27(17-15-25)35(29-13-9-12-26(22-29)32-31(37)38-3)28-18-20-33(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3,(H,32,37)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.10n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299393
PNG
(4-((1-benzylpiperidin-4-yl)(3-carbamoylphenyl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(N)=O
Show InChI InChI=1S/C30H36N4O2/c1-3-33(4-2)30(36)24-13-15-26(16-14-24)34(28-12-8-11-25(21-28)29(31)35)27-17-19-32(20-18-27)22-23-9-6-5-7-10-23/h5-16,21,27H,3-4,17-20,22H2,1-2H3,(H2,31,35)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 0.300n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299389
PNG
(4-((1-benzylpiperidin-4-yl)(3-(methylsulfonamido)p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NS(C)(=O)=O)c1
Show InChI InChI=1S/C30H38N4O3S/c1-4-33(5-2)30(35)25-14-16-27(17-15-25)34(29-13-9-12-26(22-29)31-38(3,36)37)28-18-20-32(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28,31H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.5n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299382
PNG
(4-((3-acetylphenyl)(1-benzylpiperidin-4-yl)amino)-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(C)=O
Show InChI InChI=1S/C31H37N3O2/c1-4-33(5-2)31(36)26-14-16-28(17-15-26)34(30-13-9-12-27(22-30)24(3)35)29-18-20-32(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,29H,4-5,18-21,23H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 7.90n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299388
PNG
(4-((3-acetamidophenyl)(1-benzylpiperidin-4-yl)amin...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(NC(C)=O)c1
Show InChI InChI=1S/C31H38N4O2/c1-4-34(5-2)31(37)26-14-16-28(17-15-26)35(30-13-9-12-27(22-30)32-24(3)36)29-18-20-33(21-19-29)23-25-10-7-6-8-11-25/h6-17,22,29H,4-5,18-21,23H2,1-3H3,(H,32,36)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 6.90n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299384
PNG
(4-((1-benzylpiperidin-4-yl)(3-formylphenyl)amino)-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(C=O)c1
Show InChI InChI=1S/C30H35N3O2/c1-3-32(4-2)30(35)26-13-15-27(16-14-26)33(29-12-8-11-25(21-29)23-34)28-17-19-31(20-18-28)22-24-9-6-5-7-10-24/h5-16,21,23,28H,3-4,17-20,22H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 17n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299395
PNG
(4-((1-benzylpiperidin-4-yl)(3-((dimethylamino)meth...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CN(C)C)c1
Show InChI InChI=1S/C32H42N4O/c1-5-35(6-2)32(37)28-15-17-29(18-16-28)36(31-14-10-13-27(23-31)24-33(3)4)30-19-21-34(22-20-30)25-26-11-8-7-9-12-26/h7-18,23,30H,5-6,19-22,24-25H2,1-4H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 277n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299391
PNG
(4-((3-aminophenyl)(1-benzylpiperidin-4-yl)amino)-N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(N)c1
Show InChI InChI=1S/C29H36N4O/c1-3-32(4-2)29(34)24-13-15-26(16-14-24)33(28-12-8-11-25(30)21-28)27-17-19-31(20-18-27)22-23-9-6-5-7-10-23/h5-16,21,27H,3-4,17-20,22,30H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 19n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299396
PNG
(4-((1-benzylpiperidin-4-yl)(3-(hydroxymethyl)pheny...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(CO)c1
Show InChI InChI=1S/C30H37N3O2/c1-3-32(4-2)30(35)26-13-15-27(16-14-26)33(29-12-8-11-25(21-29)23-34)28-17-19-31(20-18-28)22-24-9-6-5-7-10-24/h5-16,21,28,34H,3-4,17-20,22-23H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 133n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299392
PNG
(4-((1-benzylpiperidin-4-yl)(3-(methylcarbamoyl)phe...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(=O)NC
Show InChI InChI=1S/C31H38N4O2/c1-4-34(5-2)31(37)25-14-16-27(17-15-25)35(29-13-9-12-26(22-29)30(36)32-3)28-18-20-33(21-19-28)23-24-10-7-6-8-11-24/h6-17,22,28H,4-5,18-21,23H2,1-3H3,(H,32,36)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 151n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50299385
PNG
(4-((1-benzylpiperidin-4-yl)(3-hydroxyphenyl)amino)...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(O)c1
Show InChI InChI=1S/C29H35N3O2/c1-3-31(4-2)29(34)24-13-15-25(16-14-24)32(27-11-8-12-28(33)21-27)26-17-19-30(20-18-26)22-23-9-6-5-7-10-23/h5-16,21,26,33H,3-4,17-20,22H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 0.560n/an/an/an/a



AstraZeneca R&D Montr£al

Curated by ChEMBL


Assay Description
Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay


Bioorg Med Chem Lett 19: 5999-6003 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.068
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%