Affinity Data by PubMed id=19822431

PubMed code 19822431

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304608 (5,5'-(propane-1,3-diyl)bis(1,3,4-oxadiazole-2(3H)-...) Show SMILES Sc1nnc(CCCc2nnc(S)o2)o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysis				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304607 (5-(3-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...) Show SMILES Sc1nnc(o1)-c1cccc(OCc2ccccc2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysis				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304609 (5-[4-t-Butyldimethylsilyloxy phenyl]-1,3,4-oxadiaz...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysis				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304605 (5-(4-hydroxyphenyl)-1,3,4-thiadiazole-2(3H)-thione...) Show SMILES Oc1ccc(cc1)-c1nnc(S)s1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysis				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304606 (5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...) Show SMILES Sc1nnc(o1)-c1ccc(OCc2ccccc2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysis				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304609 (5-[4-t-Butyldimethylsilyloxy phenyl]-1,3,4-oxadiaz...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.68E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304608 (5,5'-(propane-1,3-diyl)bis(1,3,4-oxadiazole-2(3H)-...) Show SMILES Sc1nnc(CCCc2nnc(S)o2)o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.67E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304607 (5-(3-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...) Show SMILES Sc1nnc(o1)-c1cccc(OCc2ccccc2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304606 (5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...) Show SMILES Sc1nnc(o1)-c1ccc(OCc2ccccc2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304605 (5-(4-hydroxyphenyl)-1,3,4-thiadiazole-2(3H)-thione...) Show SMILES Oc1ccc(cc1)-c1nnc(S)s1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304604 (5-(pyridin-4-yl)-1,3,4-thiadiazole-2(3H)-thione \| ...) Show SMILES Sc1nnc(s1)-c1ccncc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304602 (5-(4-(tert-butyldimethylsilyloxy)phenyl)-1,3,4-thi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50304603 (5,5'-methylenebis(1,3,4-oxadiazole-2(3H)-thione) \|...) Show SMILES Sc1nnc(Cc2nnc(S)o2)o1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry				Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%