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PubMed code 19850473

Compile data set for download or QSAR
Found 30 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303019
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14BrCl2F3N6OS/c1-11-31-33-21(38-11)17-18(20-32-34-22(37-20)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 1.72n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303018
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H18BrCl3N6OS/c1-15-34-36-27(41-15)23-24(26-35-37-28(40-26)29(12-13-29)17-4-8-19(31)9-5-17)38-39(22-11-10-20(32)14-21(22)33)25(23)16-2-6-18(30)7-3-16/h2-11,14H,12-13H2,1H3
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n/an/a 2.13n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303014
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C(C)(C)C
Show InChI InChI=1S/C24H19BrCl2N6O2/c1-12-28-29-21(34-12)18-19(22-30-31-23(35-22)24(2,3)4)32-33(17-10-9-15(26)11-16(17)27)20(18)13-5-7-14(25)8-6-13/h5-11H,1-4H3
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n/an/a 2.56n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303027
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C(C)(C)C
Show InChI InChI=1S/C24H19BrCl2N6S2/c1-12-28-29-21(34-12)18-19(22-30-31-23(35-22)24(2,3)4)32-33(17-10-9-15(26)11-16(17)27)20(18)13-5-7-14(25)8-6-13/h5-11H,1-4H3
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n/an/a 2.56n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303011
PNG
(2-tert-butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichloro...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C(C)(C)C
Show InChI InChI=1S/C24H19Cl3N6OS/c1-12-28-30-22(35-12)18-19(21-29-31-23(34-21)24(2,3)4)32-33(17-10-9-15(26)11-16(17)27)20(18)13-5-7-14(25)8-6-13/h5-11H,1-4H3
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n/an/a 2.83n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303022
PNG
(2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-(5-...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H18Cl4N6S2/c1-15-34-35-26(40-15)23-24(27-36-37-28(41-27)29(12-13-29)17-4-8-19(31)9-5-17)38-39(22-11-10-20(32)14-21(22)33)25(23)16-2-6-18(30)7-3-16/h2-11,14H,12-13H2,1H3
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n/an/a 3.03n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303020
PNG
(2-(5-(4-chlorophenyl)-3-(5-(1-(4-chlorophenyl)cycl...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H18Cl4N6OS/c1-15-34-35-26(40-15)23-24(27-36-37-28(41-27)29(12-13-29)17-4-8-19(31)9-5-17)38-39(22-11-10-20(32)14-21(22)33)25(23)16-2-6-18(30)7-3-16/h2-11,14H,12-13H2,1H3
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n/an/a 3.23n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303017
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C(C)(C)C
Show InChI InChI=1S/C24H19BrCl2N6OS/c1-12-28-30-22(35-12)18-19(21-29-31-23(34-21)24(2,3)4)32-33(17-10-9-15(26)11-16(17)27)20(18)13-5-7-14(25)8-6-13/h5-11H,1-4H3
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n/an/a 3.69n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303028
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H18BrCl3N6S2/c1-15-34-35-26(40-15)23-24(27-36-37-28(41-27)29(12-13-29)17-4-8-19(31)9-5-17)38-39(22-11-10-20(32)14-21(22)33)25(23)16-2-6-18(30)7-3-16/h2-11,14H,12-13H2,1H3
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n/an/a 3.70n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303009
PNG
(2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-(5-...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H18Cl4N6O2/c1-15-34-35-26(40-15)23-24(27-36-37-28(41-27)29(12-13-29)17-4-8-19(31)9-5-17)38-39(22-11-10-20(32)14-21(22)33)25(23)16-2-6-18(30)7-3-16/h2-11,14H,12-13H2,1H3
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n/an/a 3.93n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303013
PNG
(2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-(5-...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14Cl3F3N6OS/c1-11-31-33-21(38-11)17-18(20-32-34-22(37-20)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 4.14n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303029
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-3-(5-(...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14BrCl2F3N6S2/c1-11-31-32-20(37-11)17-18(21-33-34-22(38-21)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 4.21n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303025
PNG
(2-(5-(4-bromophenyl)-3-(5-(1-(4-chlorophenyl)cyclo...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H18BrCl3N6OS/c1-15-34-35-26(40-15)23-24(27-36-37-28(41-27)29(12-13-29)17-4-8-19(31)9-5-17)38-39(22-11-10-20(32)14-21(22)33)25(23)16-2-6-18(30)7-3-16/h2-11,14H,12-13H2,1H3
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n/an/a 4.44n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303016
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-3-(5-(...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14BrCl2F3N6O2/c1-11-31-32-20(37-11)17-18(21-33-34-22(38-21)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 4.70n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303026
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-3-(5-(...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14BrCl2F3N6OS/c1-11-31-32-20(37-11)17-18(21-33-34-22(38-21)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 4.86n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303015
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H18BrCl3N6O2/c1-15-34-35-26(40-15)23-24(27-36-37-28(41-27)29(12-13-29)17-4-8-19(31)9-5-17)38-39(22-11-10-20(32)14-21(22)33)25(23)16-2-6-18(30)7-3-16/h2-11,14H,12-13H2,1H3
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n/an/a 4.91n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303024
PNG
(2-(5-(4-bromophenyl)-3-(5-tert-butyl-1,3,4-thiadia...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C(C)(C)C
Show InChI InChI=1S/C24H19BrCl2N6OS/c1-12-28-29-21(34-12)18-19(22-30-31-23(35-22)24(2,3)4)32-33(17-10-9-15(26)11-16(17)27)20(18)13-5-7-14(25)8-6-13/h5-11H,1-4H3
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n/an/a 4.93n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 5n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303008
PNG
(2-tert-butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichloro...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C(C)(C)C
Show InChI InChI=1S/C24H19Cl3N6O2/c1-12-28-29-21(34-12)18-19(22-30-31-23(35-22)24(2,3)4)32-33(17-10-9-15(26)11-16(17)27)20(18)13-5-7-14(25)8-6-13/h5-11H,1-4H3
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n/an/a 6.47n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303023
PNG
(2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14Cl3F3N6S2/c1-11-31-32-20(37-11)17-18(21-33-34-22(38-21)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 7.39n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303012
PNG
(2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-(5-...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H18Cl4N6OS/c1-15-34-36-27(41-15)23-24(26-35-37-28(40-26)29(12-13-29)17-4-8-19(31)9-5-17)38-39(22-11-10-20(32)14-21(22)33)25(23)16-2-6-18(30)7-3-16/h2-11,14H,12-13H2,1H3
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n/an/a 10.3n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303010
PNG
(2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14Cl3F3N6O2/c1-11-31-32-20(37-11)17-18(21-33-34-22(38-21)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 14.7n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM50303021
PNG
(2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14Cl3F3N6OS/c1-11-31-32-20(37-11)17-18(21-33-34-22(38-21)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 26.9n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM50303019
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14BrCl2F3N6OS/c1-11-31-33-21(38-11)17-18(20-32-34-22(37-20)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 38.5n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in CHO cells by luciferase reporter gene assay

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 92.5n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in CHO cells by luciferase reporter gene assay

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM50303019
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)C(F)(F)F
Show InChI InChI=1S/C24H14BrCl2F3N6OS/c1-11-31-33-21(38-11)17-18(20-32-34-22(37-20)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3
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n/an/a 245n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN552122 from human CB2 receptor expressed in CHOK1 cells

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM50303014
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(o1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C(C)(C)C
Show InChI InChI=1S/C24H19BrCl2N6O2/c1-12-28-29-21(34-12)18-19(22-30-31-23(35-22)24(2,3)4)32-33(17-10-9-15(26)11-16(17)27)20(18)13-5-7-14(25)8-6-13/h5-11H,1-4H3
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n/an/a 414n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN552122 from human CB2 receptor expressed in CHOK1 cells

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM50303027
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C(C)(C)C
Show InChI InChI=1S/C24H19BrCl2N6S2/c1-12-28-29-21(34-12)18-19(22-30-31-23(35-22)24(2,3)4)32-33(17-10-9-15(26)11-16(17)27)20(18)13-5-7-14(25)8-6-13/h5-11H,1-4H3
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n/an/a 427n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN552122 from human CB2 receptor expressed in CHOK1 cells

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 1.76E+3n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN552122 from human CB2 receptor expressed in CHOK1 cells

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM50303028
PNG
(2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...)
Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H18BrCl3N6S2/c1-15-34-35-26(40-15)23-24(27-36-37-28(41-27)29(12-13-29)17-4-8-19(31)9-5-17)38-39(22-11-10-20(32)14-21(22)33)25(23)16-2-6-18(30)7-3-16/h2-11,14H,12-13H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]WIN552122 from human CB2 receptor expressed in CHOK1 cells

Bioorg Med Chem Lett 19: 6632-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.015
BindingDB Entry DOI: 10.7270/Q2NC6191
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%