Affinity Data by PubMed id=19854643

PubMed code 19854643

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50299814 ((S)-N-((8S,11S,14S,17S,20R,23S)-1,27-diamino-11,17...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	575	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of HDAC6				Bioorg Med Chem Lett 19: 6588-90 (2009) Article DOI: 10.1016/j.bmcl.2009.10.028 BindingDB Entry DOI: 10.7270/Q2QV3NFK
School of Chemistry and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50299816 ((S)-N-((8S,11S,14S,17S,20R,23S)-1,27-diamino-11,17...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	714	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of HDAC6				Bioorg Med Chem Lett 19: 6588-90 (2009) Article DOI: 10.1016/j.bmcl.2009.10.028 BindingDB Entry DOI: 10.7270/Q2QV3NFK
School of Chemistry and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50299815 ((S)-N-((8S,11S,14S,17S,20R,23S)-1,27-diamino-11,17...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	716	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of HDAC6				Bioorg Med Chem Lett 19: 6588-90 (2009) Article DOI: 10.1016/j.bmcl.2009.10.028 BindingDB Entry DOI: 10.7270/Q2QV3NFK
School of Chemistry and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of HDAC6				Bioorg Med Chem Lett 19: 6588-90 (2009) Article DOI: 10.1016/j.bmcl.2009.10.028 BindingDB Entry DOI: 10.7270/Q2QV3NFK
School of Chemistry and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50299816 ((S)-N-((8S,11S,14S,17S,20R,23S)-1,27-diamino-11,17...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of HDAC8				Bioorg Med Chem Lett 19: 6588-90 (2009) Article DOI: 10.1016/j.bmcl.2009.10.028 BindingDB Entry DOI: 10.7270/Q2QV3NFK
School of Chemistry and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50299815 ((S)-N-((8S,11S,14S,17S,20R,23S)-1,27-diamino-11,17...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of HDAC8				Bioorg Med Chem Lett 19: 6588-90 (2009) Article DOI: 10.1016/j.bmcl.2009.10.028 BindingDB Entry DOI: 10.7270/Q2QV3NFK
School of Chemistry and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of HDAC8				Bioorg Med Chem Lett 19: 6588-90 (2009) Article DOI: 10.1016/j.bmcl.2009.10.028 BindingDB Entry DOI: 10.7270/Q2QV3NFK
School of Chemistry and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50299814 ((S)-N-((8S,11S,14S,17S,20R,23S)-1,27-diamino-11,17...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of HDAC8				Bioorg Med Chem Lett 19: 6588-90 (2009) Article DOI: 10.1016/j.bmcl.2009.10.028 BindingDB Entry DOI: 10.7270/Q2QV3NFK
School of Chemistry and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%