Found 28 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414894
(CHEMBL573760)Show SMILES COc1cc2C(=O)c3c(NCc4c(Cl)cccc4Cl)[nH]nc3-c2cc1OC Show InChI InChI=1S/C19H15Cl2N3O3/c1-26-14-6-9-10(7-15(14)27-2)18(25)16-17(9)23-24-19(16)22-8-11-12(20)4-3-5-13(11)21/h3-7H,8H2,1-2H3,(H2,22,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414893
(CHEMBL578426)Show InChI InChI=1S/C21H23N3O2/c1-12-6-5-7-13(2)17(12)11-22-21-16-8-14-9-18(25-3)19(26-4)10-15(14)20(16)23-24-21/h5-7,9-10H,8,11H2,1-4H3,(H2,22,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414892
(CHEMBL576168)Show SMILES COc1cc2Cc3c(NCc4c(C)cccc4Cl)[nH]nc3-c2cc1OC Show InChI InChI=1S/C20H20ClN3O2/c1-11-5-4-6-16(21)15(11)10-22-20-14-7-12-8-17(25-2)18(26-3)9-13(12)19(14)23-24-20/h4-6,8-9H,7,10H2,1-3H3,(H2,22,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414891
(CHEMBL574005)Show SMILES COc1cc-2c(Cc3c(NCc4c(Cl)cccc4Cl)[nH]nc-23)cc1OCC(O)CO Show InChI InChI=1S/C21H21Cl2N3O4/c1-29-18-7-13-11(6-19(18)30-10-12(28)9-27)5-14-20(13)25-26-21(14)24-8-15-16(22)3-2-4-17(15)23/h2-4,6-7,12,27-28H,5,8-10H2,1H3,(H2,24,25,26) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414895
(CHEMBL578836)Show InChI InChI=1S/C19H18ClN3O/c1-11-4-3-5-17(20)16(11)10-21-19-15-8-12-6-7-13(24-2)9-14(12)18(15)22-23-19/h3-7,9H,8,10H2,1-2H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414890
(CHEMBL565272)Show SMILES COc1cc2oc3c(NCc4c(Cl)cccc4Cl)[nH]nc3c2cc1OC | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414889
(CHEMBL574443)Show InChI InChI=1S/C20H21N3O2/c1-12-6-4-5-7-13(12)11-21-20-16-8-14-9-17(24-2)18(25-3)10-15(14)19(16)22-23-20/h4-7,9-10H,8,11H2,1-3H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414888
(CHEMBL583635)Show SMILES COc1cc2-c3n[nH]c(NCc4c(Cl)cccc4Cl)c3S(=O)(=O)c2cc1OC Show InChI InChI=1S/C18H15Cl2N3O4S/c1-26-13-6-9-15(7-14(13)27-2)28(24,25)17-16(9)22-23-18(17)21-8-10-11(19)4-3-5-12(10)20/h3-7H,8H2,1-2H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 79.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414887
(CHEMBL574209)Show SMILES COc1cc-2c(Cc3c(NCc4c(C)cccc4Cl)[nH]nc-23)c(OC)c1 Show InChI InChI=1S/C20H20ClN3O2/c1-11-5-4-6-17(21)16(11)10-22-20-15-9-13-14(19(15)23-24-20)7-12(25-2)8-18(13)26-3/h4-8H,9-10H2,1-3H3,(H2,22,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414886
(CHEMBL573763)Show InChI InChI=1S/C19H18ClN3O2/c1-24-16-8-12-7-14-18(13(12)9-17(16)25-2)22-23-19(14)21-10-11-5-3-4-6-15(11)20/h3-6,8-9H,7,10H2,1-2H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414885
(CHEMBL574009)Show SMILES CN(C)c1ccc2Cc3c(NCc4c(C)cccc4Cl)[nH]nc3-c2c1 Show InChI InChI=1S/C20H21ClN4/c1-12-5-4-6-18(21)17(12)11-22-20-16-9-13-7-8-14(25(2)3)10-15(13)19(16)23-24-20/h4-8,10H,9,11H2,1-3H3,(H2,22,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414884
(CHEMBL573770)Show SMILES Cc1cccc(Cl)c1CNc1[nH]nc-2c1Cc1cc3OCOc3cc-21 Show InChI InChI=1S/C19H16ClN3O2/c1-10-3-2-4-15(20)14(10)8-21-19-13-5-11-6-16-17(25-9-24-16)7-12(11)18(13)22-23-19/h2-4,6-7H,5,8-9H2,1H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414883
(CHEMBL576948)Show InChI InChI=1S/C20H20ClN3/c1-3-13-7-8-14-10-16-19(15(14)9-13)23-24-20(16)22-11-17-12(2)5-4-6-18(17)21/h4-9H,3,10-11H2,1-2H3,(H2,22,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414881
(CHEMBL575913)Show SMILES COc1ccc-2c(Cc3c(NCc4c(C)cccc4Cl)[nH]nc-23)c1 Show InChI InChI=1S/C19H18ClN3O/c1-11-4-3-5-17(20)16(11)10-21-19-15-9-12-8-13(24-2)6-7-14(12)18(15)22-23-19/h3-8H,9-10H2,1-2H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414882
(CHEMBL582642) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414880
(CHEMBL574208)Show InChI InChI=1S/C19H19N3O2/c1-23-16-9-13-8-15-18(14(13)10-17(16)24-2)21-22-19(15)20-11-12-6-4-3-5-7-12/h3-7,9-10H,8,11H2,1-2H3,(H2,20,21,22) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414878
(CHEMBL575914)Show InChI InChI=1S/C19H18ClN3O/c1-11-5-3-7-16(20)15(11)10-21-19-14-9-13-12(18(14)22-23-19)6-4-8-17(13)24-2/h3-8H,9-10H2,1-2H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414879
(CHEMBL573280)Show InChI InChI=1S/C18H15BrClN3/c1-10-3-2-4-16(20)15(10)9-21-18-14-7-11-5-6-12(19)8-13(11)17(14)22-23-18/h2-6,8H,7,9H2,1H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414877
(CHEMBL574006)Show InChI InChI=1S/C19H18ClN3O2/c1-24-16-8-12-7-15-18(14(12)9-17(16)25-2)22-23-19(15)21-10-11-4-3-5-13(20)6-11/h3-6,8-9H,7,10H2,1-2H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414876
(CHEMBL575078)Show InChI InChI=1S/C19H18ClN3S/c1-11-4-3-5-17(20)16(11)10-21-19-15-8-12-6-7-13(24-2)9-14(12)18(15)22-23-19/h3-7,9H,8,10H2,1-2H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414875
(CHEMBL575915)Show SMILES COc1cc2Cc3c(NCc4ccc(Cl)cc4Cl)[nH]nc3-c2cc1OC Show InChI InChI=1S/C19H17Cl2N3O2/c1-25-16-6-11-5-14-18(13(11)8-17(16)26-2)23-24-19(14)22-9-10-3-4-12(20)7-15(10)21/h3-4,6-8H,5,9H2,1-2H3,(H2,22,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414874
(CHEMBL583189)Show InChI InChI=1S/C18H16ClN3/c1-11-5-4-8-16(19)15(11)10-20-18-14-9-12-6-2-3-7-13(12)17(14)21-22-18/h2-8H,9-10H2,1H3,(H2,20,21,22) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414872
(CHEMBL574010)Show InChI InChI=1S/C19H18ClN3O2/c1-24-16-8-12-7-15-18(14(12)9-17(16)25-2)22-23-19(15)21-10-11-3-5-13(20)6-4-11/h3-6,8-9H,7,10H2,1-2H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414873
(CHEMBL578663)Show SMILES COc1cc2Cc3c(NCc4c(Cl)cccc4Cl)[nH]nc3-c2cc1OC Show InChI InChI=1S/C19H17Cl2N3O2/c1-25-16-7-10-6-12-18(11(10)8-17(16)26-2)23-24-19(12)22-9-13-14(20)4-3-5-15(13)21/h3-5,7-8H,6,9H2,1-2H3,(H2,22,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414871
(CHEMBL577153)Show SMILES COc1ccccc1CNc1[nH]nc-2c1Cc1cc(OC)c(OC)cc-21 Show InChI InChI=1S/C20H21N3O3/c1-24-16-7-5-4-6-12(16)11-21-20-15-8-13-9-17(25-2)18(26-3)10-14(13)19(15)22-23-20/h4-7,9-10H,8,11H2,1-3H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414870
(CHEMBL566756)Show SMILES COc1cc2CCCc3c(NCc4c(Cl)cccc4Cl)[nH]nc3-c2cc1OC Show InChI InChI=1S/C21H21Cl2N3O2/c1-27-18-9-12-5-3-6-13-20(14(12)10-19(18)28-2)25-26-21(13)24-11-15-16(22)7-4-8-17(15)23/h4,7-10H,3,5-6,11H2,1-2H3,(H2,24,25,26) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414868
(CHEMBL574630)Show InChI InChI=1S/C19H18ClN3O/c1-11-5-3-7-15(20)14(11)10-21-19-13-9-12-6-4-8-16(24-2)17(12)18(13)22-23-19/h3-8H,9-10H2,1-2H3,(H2,21,22,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
Eukaryotic translation initiation factor 2-alpha kinase 1
(Homo sapiens (Human)) | BDBM50414869
(CHEMBL566755)Show SMILES COc1cc2CCc3c(NCc4c(Cl)cccc4Cl)[nH]nc3-c2cc1OC Show InChI InChI=1S/C20H19Cl2N3O2/c1-26-17-8-11-6-7-12-19(13(11)9-18(17)27-2)24-25-20(12)23-10-14-15(21)4-3-5-16(14)22/h3-5,8-9H,6-7,10H2,1-2H3,(H2,23,24,25) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human HRI kinase |
Bioorg Med Chem Lett 19: 6548-51 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ |
More data for this
Ligand-Target Pair | |
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