BindingDB logo
myBDB logout

PubMed code 19880317

Compile data set for download or QSAR
Found 50 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 113n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM22360
PNG
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Show SMILES CC(=O)Oc1ccccc1C(O)=O
Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 411n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM22360
PNG
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Show SMILES CC(=O)Oc1ccccc1C(O)=O
Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.53E+3n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303146
PNG
(CHEMBL571199 | Neolignan 9-nor-7,8-dehydro-isolica...)
Show SMILES COc1cc(CC=C)cc2cc(oc12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C19H16O4/c1-3-4-12-7-14-10-16(23-19(14)18(8-12)20-2)13-5-6-15-17(9-13)22-11-21-15/h3,5-10H,1,4,11H2,2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.32E+3n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303141
PNG
(CHEMBL570290 | Nectamazin C)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@H](C)[C@]2(OC)C=C(CC=C)[C@H](O)[C@]1(OC)[C@H]2O |r,t:19,TLB:4:12:28:18.19.23,20:19:28:13.12,24:23:28:13.12,THB:14:13:28:18.19.23|
Show InChI InChI=1S/C23H32O7/c1-8-9-14-12-22(29-6)13(2)18(23(30-7,20(14)24)21(22)25)15-10-16(26-3)19(28-5)17(11-15)27-4/h8,10-13,18,20-21,24-25H,1,9H2,2-7H3/t13-,18+,20-,21-,22+,23-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.83E+3n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 8.32E+3n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303153
PNG
(CHEMBL571617 | Ocophyllals B)
Show SMILES COc1cc(cc(OC)c1OC)-c1oc2c(OC)cc(C=O)cc2c1C
Show InChI InChI=1S/C20H20O6/c1-11-14-6-12(10-21)7-15(22-2)19(14)26-18(11)13-8-16(23-3)20(25-5)17(9-13)24-4/h6-10H,1-5H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.27E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303152
PNG
(CHEMBL571616 | Ocophyllals A)
Show SMILES COc1cc(C=O)cc2c(C)c(oc12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C18H14O5/c1-10-13-5-11(8-19)6-16(20-2)18(13)23-17(10)12-3-4-14-15(7-12)22-9-21-14/h3-8H,9H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.68E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303145
PNG
(2'-epi-guianin | CHEMBL570978)
Show SMILES C[C@@H]1[C@H](C2[C@H](O)[C@@]1(CC=C)C=C(CC=C)C2=O)c1ccc2OCOc2c1 |r,t:11,TLB:12:11:4:1.2,0:1:4:10.11.15,5:4:1.2:10.11.15,16:15:4:1.2,THB:17:2:4:10.11.15|
Show InChI InChI=1S/C22H24O4/c1-4-6-15-11-22(9-5-2)13(3)18(19(20(15)23)21(22)24)14-7-8-16-17(10-14)26-12-25-16/h4-5,7-8,10-11,13,18-19,21,24H,1-2,6,9,12H2,3H3/t13-,18+,19?,21+,22+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.82E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303147
PNG
((-)-licarin B | CHEMBL578403)
Show SMILES COc1cc(\C=C\C)cc2[C@H](C)[C@H](Oc12)c1ccc2OCOc2c1 |r|
Show InChI InChI=1S/C20H20O4/c1-4-5-13-8-15-12(2)19(24-20(15)18(9-13)21-3)14-6-7-16-17(10-14)23-11-22-16/h4-10,12,19H,11H2,1-3H3/b5-4+/t12-,19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.56E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50001747
PNG
((+)-Kadsurenone | (Kadsurenone)5-Allyl-2-(3,4-dime...)
Show SMILES COc1ccc(cc1OC)[C@H]1OC2=CC(=O)C(CC=C)=C[C@]2(OC)[C@@H]1C |c:20,t:13|
Show InChI InChI=1S/C21H24O5/c1-6-7-15-12-21(25-5)13(2)20(26-19(21)11-16(15)22)14-8-9-17(23-3)18(10-14)24-4/h6,8-13,20H,1,7H2,2-5H3/t13-,20+,21+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.56E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50378548
PNG
(CINERIN C)
Show SMILES COc1cc(cc2OCOc12)C1C(C)C2(OC)C=C(CC=C)C(=O)C1(OC)C2O |t:19,THB:13:12:17.22.18:27,4:11:17.22.18:27,19:18:11.12:27,28:27:11.12:17.22.18,23:22:11.12:27|
Show InChI InChI=1S/C22H26O7/c1-6-7-13-10-21(26-4)12(2)17(22(27-5,19(13)23)20(21)24)14-8-15(25-3)18-16(9-14)28-11-29-18/h6,8-10,12,17,20,24H,1,7,11H2,2-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.83E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303154
PNG
((+)-Acuminatin | CHEMBL571195 | acuminatin)
Show SMILES COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1ccc(OC)c(OC)c1 |r|
Show InChI InChI=1S/C21H24O4/c1-6-7-14-10-16-13(2)20(25-21(16)19(11-14)24-5)15-8-9-17(22-3)18(12-15)23-4/h6-13,20H,1-5H3/b7-6+/t13-,20-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.87E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303149
PNG
((-)-licarin A | CHEMBL463526 | Licarin A)
Show SMILES COc1cc(\C=C\C)cc2[C@H](C)[C@H](Oc12)c1ccc(O)c(OC)c1 |r|
Show InChI InChI=1S/C20H22O4/c1-5-6-13-9-15-12(2)19(24-20(15)18(10-13)23-4)14-7-8-16(21)17(11-14)22-3/h5-12,19,21H,1-4H3/b6-5+/t12-,19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.21E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303142
PNG
(CHEMBL571615 | Kadsurenin C)
Show SMILES COc1ccc(cc1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@@H]1[C@@H]2O |r,t:17,TLB:25:24:10.11:21.17.16,18:17:24:10.11,12:11:24:21.17.16,THB:22:21:24:10.11,5:10:24:21.17.16|
Show InChI InChI=1S/C21H26O5/c1-6-7-14-11-21(26-5)12(2)17(18(19(14)22)20(21)23)13-8-9-15(24-3)16(10-13)25-4/h6,8-12,17-18,20,23H,1,7H2,2-5H3/t12-,17+,18-,20+,21-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.87E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303148
PNG
((+)-licarin B | CHEMBL259386 | licarine B)
Show SMILES COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1ccc2OCOc2c1 |r|
Show InChI InChI=1S/C20H20O4/c1-4-5-13-8-15-12(2)19(24-20(15)18(9-13)21-3)14-6-7-16-17(10-14)23-11-22-16/h4-10,12,19H,11H2,1-3H3/b5-4+/t12-,19-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 5.21E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303144
PNG
(CHEMBL585912 | Macrophyllin B)
Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)[C@@H](O)C1C2=O |r,t:19,TLB:4:12:26:18.19.23,20:19:26:13.12,27:26:13.12:18.19.23,24:23:26:13.12,THB:14:13:26:18.19.23|
Show InChI InChI=1S/C22H28O6/c1-7-8-13-11-22(28-6)12(2)17(18(19(13)23)21(22)24)14-9-15(25-3)20(27-5)16(10-14)26-4/h7,9-12,17-19,23H,1,8H2,2-6H3/t12-,17+,18?,19-,22-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.54E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303150
PNG
((+)-licarin A | CHEMBL259731 | licarin A | licarin...)
Show SMILES COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1ccc(O)c(OC)c1 |r|
Show InChI InChI=1S/C20H22O4/c1-5-6-13-9-15-12(2)19(24-20(15)18(10-13)23-4)14-7-8-16(21)17(11-14)22-3/h5-12,19,21H,1-4H3/b6-5+/t12-,19-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.64E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303138
PNG
(CHEMBL570318 | Ocophylol C)
Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@@H]1[C@H]2O |r,t:19,TLB:27:26:12.13:23.19.18,20:19:26:12.13,14:13:26:23.19.18,THB:24:23:26:12.13,4:12:26:23.19.18|
Show InChI InChI=1S/C22H28O6/c1-7-8-13-11-22(28-6)12(2)17(18(19(13)23)21(22)24)14-9-15(25-3)20(27-5)16(10-14)26-4/h7,9-12,17-18,21,24H,1,8H2,2-6H3/t12-,17+,18-,21-,22-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.21E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303140
PNG
(CHEMBL571892 | Nectamazin B)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@]1(OC)[C@@H]2O |r,t:19,TLB:4:12:28:18.19.23,20:19:28:13.12,24:23:28:13.12,THB:14:13:28:18.19.23|
Show InChI InChI=1S/C23H30O7/c1-8-9-14-12-22(29-6)13(2)18(23(30-7,20(14)24)21(22)25)15-10-16(26-3)19(28-5)17(11-15)27-4/h8,10-13,18,21,25H,1,9H2,2-7H3/t13-,18+,21+,22+,23-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.22E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303141
PNG
(CHEMBL570290 | Nectamazin C)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@H](C)[C@]2(OC)C=C(CC=C)[C@H](O)[C@]1(OC)[C@H]2O |r,t:19,TLB:4:12:28:18.19.23,20:19:28:13.12,24:23:28:13.12,THB:14:13:28:18.19.23|
Show InChI InChI=1S/C23H32O7/c1-8-9-14-12-22(29-6)13(2)18(23(30-7,20(14)24)21(22)25)15-10-16(26-3)19(28-5)17(11-15)27-4/h8,10-13,18,20-21,24-25H,1,9H2,2-7H3/t13-,18+,20-,21-,22+,23-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.46E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303151
PNG
(CHEMBL570291 | Mirandin A)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1OC2=CC(=O)C(CC=C)=C[C@]2(OC)[C@@H]1C |r,c:22,t:15|
Show InChI InChI=1S/C22H26O6/c1-7-8-14-12-22(27-6)13(2)20(28-19(22)11-16(14)23)15-9-17(24-3)21(26-5)18(10-15)25-4/h7,9-13,20H,1,8H2,2-6H3/t13-,20+,22+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.79E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303136
PNG
(CHEMBL585724 | Ocophylol A)
Show SMILES CO[C@@]12C=C(CC=C)C(=O)[C@H]([C@H]1O)[C@@H]([C@H]2C)c1ccc2OCOc2c1 |r,t:3,TLB:9:8:11:13.14,15:14:11:8.4.3,THB:12:11:13.14:8.4.3,5:4:11:13.14,16:13:11:8.4.3|
Show InChI InChI=1S/C20H22O5/c1-4-5-13-9-20(23-3)11(2)16(17(18(13)21)19(20)22)12-6-7-14-15(8-12)25-10-24-14/h4,6-9,11,16-17,19,22H,1,5,10H2,2-3H3/t11-,16+,17-,19-,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.86E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303155
PNG
((+)-Denudatin B | CHEMBL571196)
Show SMILES COc1ccc(cc1OC)[C@@H]1OC2=CC(=O)C(CC=C)=C[C@@]2(OC)[C@@H]1C |r,c:20,t:13|
Show InChI InChI=1S/C21H24O5/c1-6-7-15-12-21(25-5)13(2)20(26-19(21)11-16(15)22)14-8-9-17(23-3)18(10-14)24-4/h6,8-13,20H,1,7H2,2-5H3/t13-,20-,21-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.86E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303135
PNG
((7S,8R,2'R,3'S,5'R)-Delta(8')-2'-hydroxy-5,5'-dime...)
Show SMILES COc1cc(cc2OCOc12)[C@@H]1[C@@H](C)[C@@]2(OC)C=C(CC=C)[C@H](O)[C@]1(OC)C2=O |r,t:19,TLB:13:12:27:22.18.17,28:27:11.12:22.18.17,19:18:27:11.12,THB:4:11:27:22.18.17,23:22:27:11.12|
Show InChI InChI=1S/C22H26O7/c1-6-7-13-10-21(26-4)12(2)17(22(27-5,19(13)23)20(21)24)14-8-15(25-3)18-16(9-14)28-11-29-18/h6,8-10,12,17,19,23H,1,7,11H2,2-5H3/t12-,17+,19+,21+,22+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.21E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303137
PNG
(CHEMBL583036 | Ocophylol B)
Show SMILES COc1ccc(cc1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@@H]1[C@H]2O |r,t:17,TLB:25:24:10.11:21.17.16,18:17:24:10.11,12:11:24:21.17.16,THB:22:21:24:10.11,5:10:24:21.17.16|
Show InChI InChI=1S/C21H26O5/c1-6-7-14-11-21(26-5)12(2)17(18(19(14)22)20(21)23)13-8-9-15(24-3)16(10-13)25-4/h6,8-12,17-18,20,23H,1,7H2,2-5H3/t12-,17+,18-,20-,21-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.49E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303156
PNG
(CHEMBL578402 | Liliflol A)
Show SMILES C[C@@H]1[C@H](Oc2cc(O)c(CC=C)cc12)c1ccc2OCOc2c1 |r|
Show InChI InChI=1S/C19H18O4/c1-3-4-12-7-14-11(2)19(23-17(14)9-15(12)20)13-5-6-16-18(8-13)22-10-21-16/h3,5-9,11,19-20H,1,4,10H2,2H3/t11-,19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.87E+4n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303153
PNG
(CHEMBL571617 | Ocophyllals B)
Show SMILES COc1cc(cc(OC)c1OC)-c1oc2c(OC)cc(C=O)cc2c1C
Show InChI InChI=1S/C20H20O6/c1-11-14-6-12(10-21)7-15(22-2)19(14)26-18(11)13-8-16(23-3)20(25-5)17(9-13)24-4/h6-10H,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.02E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303152
PNG
(CHEMBL571616 | Ocophyllals A)
Show SMILES COc1cc(C=O)cc2c(C)c(oc12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C18H14O5/c1-10-13-5-11(8-19)6-16(20-2)18(13)23-17(10)12-3-4-14-15(7-12)22-9-21-14/h3-8H,9H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.23E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303151
PNG
(CHEMBL570291 | Mirandin A)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1OC2=CC(=O)C(CC=C)=C[C@]2(OC)[C@@H]1C |r,c:22,t:15|
Show InChI InChI=1S/C22H26O6/c1-7-8-14-12-22(27-6)13(2)20(28-19(22)11-16(14)23)15-9-17(24-3)21(26-5)18(10-15)25-4/h7,9-13,20H,1,8H2,2-6H3/t13-,20+,22+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.26E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303156
PNG
(CHEMBL578402 | Liliflol A)
Show SMILES C[C@@H]1[C@H](Oc2cc(O)c(CC=C)cc12)c1ccc2OCOc2c1 |r|
Show InChI InChI=1S/C19H18O4/c1-3-4-12-7-14-11(2)19(23-17(14)9-15(12)20)13-5-6-16-18(8-13)22-10-21-16/h3,5-9,11,19-20H,1,4,10H2,2H3/t11-,19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.79E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303135
PNG
((7S,8R,2'R,3'S,5'R)-Delta(8')-2'-hydroxy-5,5'-dime...)
Show SMILES COc1cc(cc2OCOc12)[C@@H]1[C@@H](C)[C@@]2(OC)C=C(CC=C)[C@H](O)[C@]1(OC)C2=O |r,t:19,TLB:13:12:27:22.18.17,28:27:11.12:22.18.17,19:18:27:11.12,THB:4:11:27:22.18.17,23:22:27:11.12|
Show InChI InChI=1S/C22H26O7/c1-6-7-13-10-21(26-4)12(2)17(22(27-5,19(13)23)20(21)24)14-8-15(25-3)18-16(9-14)28-11-29-18/h6,8-10,12,17,19,23H,1,7,11H2,2-5H3/t12-,17+,19+,21+,22+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.88E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303144
PNG
(CHEMBL585912 | Macrophyllin B)
Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)[C@@H](O)C1C2=O |r,t:19,TLB:4:12:26:18.19.23,20:19:26:13.12,27:26:13.12:18.19.23,24:23:26:13.12,THB:14:13:26:18.19.23|
Show InChI InChI=1S/C22H28O6/c1-7-8-13-11-22(28-6)12(2)17(18(19(13)23)21(22)24)14-9-15(25-3)20(27-5)16(10-14)26-4/h7,9-12,17-19,23H,1,8H2,2-6H3/t12-,17+,18?,19-,22-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.16E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303154
PNG
((+)-Acuminatin | CHEMBL571195 | acuminatin)
Show SMILES COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1ccc(OC)c(OC)c1 |r|
Show InChI InChI=1S/C21H24O4/c1-6-7-14-10-16-13(2)20(25-21(16)19(11-14)24-5)15-8-9-17(22-3)18(12-15)23-4/h6-13,20H,1-5H3/b7-6+/t13-,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.23E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303150
PNG
((+)-licarin A | CHEMBL259731 | licarin A | licarin...)
Show SMILES COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1ccc(O)c(OC)c1 |r|
Show InChI InChI=1S/C20H22O4/c1-5-6-13-9-15-12(2)19(24-20(15)18(10-13)23-4)14-7-8-16(21)17(11-14)22-3/h5-12,19,21H,1-4H3/b6-5+/t12-,19-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.45E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303138
PNG
(CHEMBL570318 | Ocophylol C)
Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@@H]1[C@H]2O |r,t:19,TLB:27:26:12.13:23.19.18,20:19:26:12.13,14:13:26:23.19.18,THB:24:23:26:12.13,4:12:26:23.19.18|
Show InChI InChI=1S/C22H28O6/c1-7-8-13-11-22(28-6)12(2)17(18(19(13)23)21(22)24)14-9-15(25-3)20(27-5)16(10-14)26-4/h7,9-12,17-18,21,24H,1,8H2,2-6H3/t12-,17+,18-,21-,22-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.45E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50001747
PNG
((+)-Kadsurenone | (Kadsurenone)5-Allyl-2-(3,4-dime...)
Show SMILES COc1ccc(cc1OC)[C@H]1OC2=CC(=O)C(CC=C)=C[C@]2(OC)[C@@H]1C |c:20,t:13|
Show InChI InChI=1S/C21H24O5/c1-6-7-15-12-21(25-5)13(2)20(26-19(21)11-16(15)22)14-8-9-17(23-3)18(10-14)24-4/h6,8-13,20H,1,7H2,2-5H3/t13-,20+,21+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.46E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303140
PNG
(CHEMBL571892 | Nectamazin B)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@]1(OC)[C@@H]2O |r,t:19,TLB:4:12:28:18.19.23,20:19:28:13.12,24:23:28:13.12,THB:14:13:28:18.19.23|
Show InChI InChI=1S/C23H30O7/c1-8-9-14-12-22(29-6)13(2)18(23(30-7,20(14)24)21(22)25)15-10-16(26-3)19(28-5)17(11-15)27-4/h8,10-13,18,21,25H,1,9H2,2-7H3/t13-,18+,21+,22+,23-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.55E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303137
PNG
(CHEMBL583036 | Ocophylol B)
Show SMILES COc1ccc(cc1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@@H]1[C@H]2O |r,t:17,TLB:25:24:10.11:21.17.16,18:17:24:10.11,12:11:24:21.17.16,THB:22:21:24:10.11,5:10:24:21.17.16|
Show InChI InChI=1S/C21H26O5/c1-6-7-14-11-21(26-5)12(2)17(18(19(14)22)20(21)23)13-8-9-15(24-3)16(10-13)25-4/h6,8-12,17-18,20,23H,1,7H2,2-5H3/t12-,17+,18-,20-,21-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.88E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303148
PNG
((+)-licarin B | CHEMBL259386 | licarine B)
Show SMILES COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1ccc2OCOc2c1 |r|
Show InChI InChI=1S/C20H20O4/c1-4-5-13-8-15-12(2)19(24-20(15)18(9-13)21-3)14-6-7-16-17(10-14)23-11-22-16/h4-10,12,19H,11H2,1-3H3/b5-4+/t12-,19-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.89E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303142
PNG
(CHEMBL571615 | Kadsurenin C)
Show SMILES COc1ccc(cc1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@@H]1[C@@H]2O |r,t:17,TLB:25:24:10.11:21.17.16,18:17:24:10.11,12:11:24:21.17.16,THB:22:21:24:10.11,5:10:24:21.17.16|
Show InChI InChI=1S/C21H26O5/c1-6-7-14-11-21(26-5)12(2)17(18(19(14)22)20(21)23)13-8-9-15(24-3)16(10-13)25-4/h6,8-12,17-18,20,23H,1,7H2,2-5H3/t12-,17+,18-,20+,21-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.12E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303136
PNG
(CHEMBL585724 | Ocophylol A)
Show SMILES CO[C@@]12C=C(CC=C)C(=O)[C@H]([C@H]1O)[C@@H]([C@H]2C)c1ccc2OCOc2c1 |r,t:3,TLB:9:8:11:13.14,15:14:11:8.4.3,THB:12:11:13.14:8.4.3,5:4:11:13.14,16:13:11:8.4.3|
Show InChI InChI=1S/C20H22O5/c1-4-5-13-9-20(23-3)11(2)16(17(18(13)21)19(20)22)12-6-7-14-15(8-12)25-10-24-14/h4,6-9,11,16-17,19,22H,1,5,10H2,2-3H3/t11-,16+,17-,19-,20-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.12E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303149
PNG
((-)-licarin A | CHEMBL463526 | Licarin A)
Show SMILES COc1cc(\C=C\C)cc2[C@H](C)[C@H](Oc12)c1ccc(O)c(OC)c1 |r|
Show InChI InChI=1S/C20H22O4/c1-5-6-13-9-15-12(2)19(24-20(15)18(10-13)23-4)14-7-8-16(21)17(11-14)22-3/h5-12,19,21H,1-4H3/b6-5+/t12-,19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.12E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303145
PNG
(2'-epi-guianin | CHEMBL570978)
Show SMILES C[C@@H]1[C@H](C2[C@H](O)[C@@]1(CC=C)C=C(CC=C)C2=O)c1ccc2OCOc2c1 |r,t:11,TLB:12:11:4:1.2,0:1:4:10.11.15,5:4:1.2:10.11.15,16:15:4:1.2,THB:17:2:4:10.11.15|
Show InChI InChI=1S/C22H24O4/c1-4-6-15-11-22(9-5-2)13(3)18(19(20(15)23)21(22)24)14-7-8-16-17(10-14)26-12-25-16/h4-5,7-8,10-11,13,18-19,21,24H,1-2,6,9,12H2,3H3/t13-,18+,19?,21+,22+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.26E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303146
PNG
(CHEMBL571199 | Neolignan 9-nor-7,8-dehydro-isolica...)
Show SMILES COc1cc(CC=C)cc2cc(oc12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C19H16O4/c1-3-4-12-7-14-10-16(23-19(14)18(8-12)20-2)13-5-6-15-17(9-13)22-11-21-15/h3,5-10H,1,4,11H2,2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.49E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50378548
PNG
(CINERIN C)
Show SMILES COc1cc(cc2OCOc12)C1C(C)C2(OC)C=C(CC=C)C(=O)C1(OC)C2O |t:19,THB:13:12:17.22.18:27,4:11:17.22.18:27,19:18:11.12:27,28:27:11.12:17.22.18,23:22:11.12:27|
Show InChI InChI=1S/C22H26O7/c1-6-7-13-10-21(26-4)12(2)17(22(27-5,19(13)23)20(21)24)14-8-15(25-3)18-16(9-14)28-11-29-18/h6,8-10,12,17,20,24H,1,7,11H2,2-5H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.56E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303143
PNG
(4'-oxo-macrophyllin B | CHEMBL584539)
Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)C1C2=O |r,t:19,TLB:4:12:26:18.19.23,20:19:26:13.12,27:26:13.12:18.19.23,24:23:26:13.12,THB:14:13:26:18.19.23|
Show InChI InChI=1S/C22H26O6/c1-7-8-13-11-22(28-6)12(2)17(18(19(13)23)21(22)24)14-9-15(25-3)20(27-5)16(10-14)26-4/h7,9-12,17-18H,1,8H2,2-6H3/t12-,17+,18?,22-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.56E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50303147
PNG
((-)-licarin B | CHEMBL578403)
Show SMILES COc1cc(\C=C\C)cc2[C@H](C)[C@H](Oc12)c1ccc2OCOc2c1 |r|
Show InChI InChI=1S/C20H20O4/c1-4-5-13-8-15-12(2)19(24-20(15)18(9-13)21-3)14-6-7-16-17(10-14)23-11-22-16/h4-10,12,19H,11H2,1-3H3/b5-4+/t12-,19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.66E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303155
PNG
((+)-Denudatin B | CHEMBL571196)
Show SMILES COc1ccc(cc1OC)[C@@H]1OC2=CC(=O)C(CC=C)=C[C@@]2(OC)[C@@H]1C |r,c:20,t:13|
Show InChI InChI=1S/C21H24O5/c1-6-7-15-12-21(25-5)13(2)20(26-19(21)11-16(15)22)14-8-9-17(23-3)18(10-14)24-4/h6,8-13,20H,1,7H2,2-5H3/t13-,20-,21-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.46E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Ovis aries (Sheep))		BDBM50303143
PNG
(4'-oxo-macrophyllin B | CHEMBL584539)
Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)C1C2=O |r,t:19,TLB:4:12:26:18.19.23,20:19:26:13.12,27:26:13.12:18.19.23,24:23:26:13.12,THB:14:13:26:18.19.23|
Show InChI InChI=1S/C22H26O6/c1-7-8-13-11-22(28-6)12(2)17(18(19(13)23)21(22)24)14-9-15(25-3)20(27-5)16(10-14)26-4/h7,9-12,17-18H,1,8H2,2-6H3/t12-,17+,18?,22-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.44E+5n/an/an/an/an/an/a



Universidad Nacional de Colombia

Curated by ChEMBL


Assay Description
Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA

Bioorg Med Chem Lett 19: 6922-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.069
BindingDB Entry DOI: 10.7270/Q2J1043X
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%