Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50303157 (3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of CYP3A4 | J Med Chem 52: 7163-9 (2009) Article DOI: 10.1021/jm901230r BindingDB Entry DOI: 10.7270/Q24B31D7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50303157 (3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of CYP2C9 | J Med Chem 52: 7163-9 (2009) Article DOI: 10.1021/jm901230r BindingDB Entry DOI: 10.7270/Q24B31D7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50303157 (3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Inhibition of CYP2D6 | J Med Chem 52: 7163-9 (2009) Article DOI: 10.1021/jm901230r BindingDB Entry DOI: 10.7270/Q24B31D7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
