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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82141 (WIN 55212-2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | 7.30 | -46.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82135 (5-Substituted derivative, 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8.40 | -46.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82140 (4-methyl-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 15.7 | -44.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82139 (4-chloro-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 24.1 | -43.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82137 (4-methoxy-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 42.6 | -42.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82138 (N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-3-yl}meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 49.4 | -41.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82136 (5-Substituted derivative, 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 69.6 | -40.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82132 (5-Substituted derivative, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 74.6 | -40.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82131 (3-(Arylimino)-1-(2-morpholin-4-yl-ethyl)-1,3-dihyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 311 | -37.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82133 (5-Substituted derivative, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 390 | -36.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82134 (3-(Arylimino)-1-(2-morpholin-4-yl-ethyl)-1,3-dihyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 553 | -35.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
