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PubMed code 19954435

Compile data set for download or QSAR
Found 116 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84847
PNG
(1-azolyl-4-phenyl-2-butanone, 49a | CHEMBL558183)
Show SMILES C(CC1(Cn2ccnc2)OCCO1)c1ccccc1
Show InChI InChI=1S/C15H18N2O2/c1-2-4-14(5-3-1)6-7-15(18-10-11-19-15)12-17-9-8-16-13-17/h1-5,8-9,13H,6-7,10-12H2
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Article
PubMed
n/an/a 700n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84808
PNG
(1-azolyl-4-phenyl-2-butanone, 10 | 1-azolyl-4-phen...)
Show SMILES O=C(CCc1ccccc1)Cn1ncnn1
Show InChI InChI=1S/C11H12N4O/c16-11(8-15-13-9-12-14-15)7-6-10-4-2-1-3-5-10/h1-5,9H,6-8H2
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PubMed
n/an/a 2.60E+3n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84855
PNG
(1-azolyl-4-phenyl-2-butanone, 57a | CHEMBL536516)
Show SMILES OC(CCc1ccccc1)Cn1ccnc1 |w:1.0|
Show InChI InChI=1S/C13H16N2O/c16-13(10-15-9-8-14-11-15)7-6-12-4-2-1-3-5-12/h1-5,8-9,11,13,16H,6-7,10H2
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PubMed
n/an/a 6.00E+3n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84831
PNG
(1-azolyl-4-phenyl-2-butanone, 33)
Show SMILES O=C(CCc1ccccc1)Cn1cnc(n1)-c1ccccc1
Show InChI InChI=1S/C18H17N3O/c22-17(12-11-15-7-3-1-4-8-15)13-21-14-19-18(20-21)16-9-5-2-6-10-16/h1-10,14H,11-13H2
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n/an/a 9.00E+3n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84856
PNG
(1-azolyl-4-phenyl-2-butanone, 58)
Show SMILES OC(CCc1ccccc1)Cn1cncn1 |w:1.0|
Show InChI InChI=1S/C12H15N3O/c16-12(8-15-10-13-9-14-15)7-6-11-4-2-1-3-5-11/h1-5,9-10,12,16H,6-8H2
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n/an/a 1.02E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84804
PNG
(1-azolyl-4-phenyl-2-butanone, 6a | CHEMBL536514)
Show SMILES O=C(CCc1ccccc1)Cn1ccnc1
Show InChI InChI=1S/C13H14N2O/c16-13(10-15-9-8-14-11-15)7-6-12-4-2-1-3-5-12/h1-5,8-9,11H,6-7,10H2
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n/an/a 1.10E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84848
PNG
(1-azolyl-4-phenyl-2-butanone, 50)
Show SMILES C(CC1(Cn2cncn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C14H17N3O2/c1-2-4-13(5-3-1)6-7-14(18-8-9-19-14)10-17-12-15-11-16-17/h1-5,11-12H,6-10H2
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n/an/a 1.30E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84860
PNG
(1-azolyl-4-phenyl-2-butanone, 62)
Show SMILES OC(CCc1ccccc1)Cn1cnc(c1)-c1ccccc1 |w:1.0|
Show InChI InChI=1S/C19H20N2O/c22-18(12-11-16-7-3-1-4-8-16)13-21-14-19(20-15-21)17-9-5-2-6-10-17/h1-10,14-15,18,22H,11-13H2
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n/an/a 1.50E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84855
PNG
(1-azolyl-4-phenyl-2-butanone, 57a | CHEMBL536516)
Show SMILES OC(CCc1ccccc1)Cn1ccnc1 |w:1.0|
Show InChI InChI=1S/C13H16N2O/c16-13(10-15-9-8-14-11-15)7-6-12-4-2-1-3-5-12/h1-5,8-9,11,13,16H,6-7,10H2
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n/an/a 1.60E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84805
PNG
(1-azolyl-4-phenyl-2-butanone, 7)
Show SMILES O=C(CCc1ccccc1)Cn1cncn1
Show InChI InChI=1S/C12H13N3O/c16-12(8-15-10-13-9-14-15)7-6-11-4-2-1-3-5-11/h1-5,9-10H,6-8H2
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n/an/a 1.80E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84826
PNG
(1-azolyl-4-phenyl-2-butanone, 28)
Show SMILES Brc1cncn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C13H13BrN2O/c14-13-8-15-10-16(13)9-12(17)7-6-11-4-2-1-3-5-11/h1-5,8,10H,6-7,9H2
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n/an/a 2.20E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84808
PNG
(1-azolyl-4-phenyl-2-butanone, 10 | 1-azolyl-4-phen...)
Show SMILES O=C(CCc1ccccc1)Cn1ncnn1
Show InChI InChI=1S/C11H12N4O/c16-11(8-15-13-9-12-14-15)7-6-10-4-2-1-3-5-10/h1-5,9H,6-8H2
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n/an/a 3.00E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84822
PNG
(1-azolyl-4-phenyl-2-butanone, 24)
Show SMILES O=C(CCc1ccccc1)Cn1cnc(c1)-c1ccccc1
Show InChI InChI=1S/C19H18N2O/c22-18(12-11-16-7-3-1-4-8-16)13-21-14-19(20-15-21)17-9-5-2-6-10-17/h1-10,14-15H,11-13H2
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n/an/a 3.20E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84851
PNG
(1-azolyl-4-phenyl-2-butanone, 53)
Show SMILES C(CC1(Cn2cnnn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C13H16N4O2/c1-2-4-12(5-3-1)6-7-13(18-8-9-19-13)10-17-11-14-15-16-17/h1-5,11H,6-10H2
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n/an/a 3.90E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84819
PNG
(1-azolyl-4-phenyl-2-butanone, 21)
Show SMILES O=C(CCc1ccccc1)Cn1cnc(c1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C25H22N2O/c28-23(17-16-20-10-4-1-5-11-20)18-27-19-26-24(21-12-6-2-7-13-21)25(27)22-14-8-3-9-15-22/h1-15,19H,16-18H2
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n/an/a 4.00E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84857
PNG
(1-azolyl-4-phenyl-2-butanone, 59)
Show SMILES OC(CCc1ccccc1)Cn1ccnn1 |w:1.0|
Show InChI InChI=1S/C12H15N3O/c16-12(10-15-9-8-13-14-15)7-6-11-4-2-1-3-5-11/h1-5,8-9,12,16H,6-7,10H2
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n/an/a 4.40E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84856
PNG
(1-azolyl-4-phenyl-2-butanone, 58)
Show SMILES OC(CCc1ccccc1)Cn1cncn1 |w:1.0|
Show InChI InChI=1S/C12H15N3O/c16-12(8-15-10-13-9-14-15)7-6-11-4-2-1-3-5-11/h1-5,9-10,12,16H,6-8H2
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n/an/a 5.40E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84858
PNG
(1-azolyl-4-phenyl-2-butanone, 60)
Show SMILES OC(CCc1ccccc1)Cn1cnnn1 |w:1.0|
Show InChI InChI=1S/C11H14N4O/c16-11(8-15-9-12-13-14-15)7-6-10-4-2-1-3-5-10/h1-5,9,11,16H,6-8H2
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n/an/a 5.60E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84827
PNG
(1-azolyl-4-phenyl-2-butanone, 29)
Show SMILES COOCc1cncn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C15H18N2O3/c1-19-20-11-14-9-16-12-17(14)10-15(18)8-7-13-5-3-2-4-6-13/h2-6,9,12H,7-8,10-11H2,1H3
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n/an/a 6.90E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84852
PNG
(1-azolyl-4-phenyl-2-butanone, 54)
Show SMILES C(CC1(Cn2ncnn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C13H16N4O2/c1-2-4-12(5-3-1)6-7-13(18-8-9-19-13)10-17-15-11-14-16-17/h1-5,11H,6-10H2
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n/an/a 7.20E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84831
PNG
(1-azolyl-4-phenyl-2-butanone, 33)
Show SMILES O=C(CCc1ccccc1)Cn1cnc(n1)-c1ccccc1
Show InChI InChI=1S/C18H17N3O/c22-17(12-11-15-7-3-1-4-8-15)13-21-14-19-18(20-21)16-9-5-2-6-10-16/h1-10,14H,11-13H2
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n/an/a 9.00E+4n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84825
PNG
(1-azolyl-4-phenyl-2-butanone, 27)
Show SMILES COOCc1cn(CC(=O)CCc2ccccc2)cn1
Show InChI InChI=1S/C15H18N2O3/c1-19-20-11-14-9-17(12-16-14)10-15(18)8-7-13-5-3-2-4-6-13/h2-6,9,12H,7-8,10-11H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84834
PNG
(1-azolyl-4-phenyl-2-butanone, 36)
Show SMILES Brc1nc(Br)n(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C12H11Br2N3O/c13-11-15-12(14)17(16-11)8-10(18)7-6-9-4-2-1-3-5-9/h1-5H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84843
PNG
(1-azolyl-4-phenyl-2-butanone, 45)
Show SMILES COOSc1ncn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C13H15N3O3S/c1-18-19-20-13-14-10-16(15-13)9-12(17)8-7-11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84854
PNG
(1-azolyl-4-phenyl-2-butanone, 56)
Show SMILES C(CC1(Cn2cnc(c2-c2ccccc2)-c2ccccc2)OCCO1)c1ccccc1
Show InChI InChI=1S/C27H26N2O2/c1-4-10-22(11-5-1)16-17-27(30-18-19-31-27)20-29-21-28-25(23-12-6-2-7-13-23)26(29)24-14-8-3-9-15-24/h1-15,21H,16-20H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84808
PNG
(1-azolyl-4-phenyl-2-butanone, 10 | 1-azolyl-4-phen...)
Show SMILES O=C(CCc1ccccc1)Cn1ncnn1
Show InChI InChI=1S/C11H12N4O/c16-11(8-15-13-9-12-14-15)7-6-10-4-2-1-3-5-10/h1-5,9H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84810
PNG
(1-azolyl-4-phenyl-2-butanone, 12)
Show SMILES Cn1c(CC(=O)CCc2ccccc2)nc2ccccc12
Show InChI InChI=1S/C18H18N2O/c1-20-17-10-6-5-9-16(17)19-18(20)13-15(21)12-11-14-7-3-2-4-8-14/h2-10H,11-13H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84822
PNG
(1-azolyl-4-phenyl-2-butanone, 24)
Show SMILES O=C(CCc1ccccc1)Cn1cnc(c1)-c1ccccc1
Show InChI InChI=1S/C19H18N2O/c22-18(12-11-16-7-3-1-4-8-16)13-21-14-19(20-15-21)17-9-5-2-6-10-17/h1-10,14-15H,11-13H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84823
PNG
(1-azolyl-4-phenyl-2-butanone, 25)
Show SMILES Brc1cn(CC(=O)CCc2ccccc2)cn1
Show InChI InChI=1S/C13H13BrN2O/c14-13-9-16(10-15-13)8-12(17)7-6-11-4-2-1-3-5-11/h1-5,9-10H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84829
PNG
(1-azolyl-4-phenyl-2-butanone, 31)
Show SMILES CSc1ncn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C13H15N3OS/c1-18-13-14-10-16(15-13)9-12(17)8-7-11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84834
PNG
(1-azolyl-4-phenyl-2-butanone, 36)
Show SMILES Brc1nc(Br)n(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C12H11Br2N3O/c13-11-15-12(14)17(16-11)8-10(18)7-6-9-4-2-1-3-5-9/h1-5H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84846
PNG
(1-azolyl-4-phenyl-2-butanone, 48)
Show SMILES COOSc1nnn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C12H14N4O3S/c1-18-19-20-12-13-15-16(14-12)9-11(17)8-7-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84847
PNG
(1-azolyl-4-phenyl-2-butanone, 49a | CHEMBL558183)
Show SMILES C(CC1(Cn2ccnc2)OCCO1)c1ccccc1
Show InChI InChI=1S/C15H18N2O2/c1-2-4-14(5-3-1)6-7-15(18-10-11-19-15)12-17-9-8-16-13-17/h1-5,8-9,13H,6-7,10-12H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84814
PNG
(1-azolyl-4-phenyl-2-butanone, 16)
Show SMILES O=C(CCc1ccccc1)Cn1ccnc1-c1ccccc1
Show InChI InChI=1S/C19H18N2O/c22-18(12-11-16-7-3-1-4-8-16)15-21-14-13-20-19(21)17-9-5-2-6-10-17/h1-10,13-14H,11-12,15H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84828
PNG
(1-azolyl-4-phenyl-2-butanone, 30)
Show SMILES COOCc1ncn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C14H17N3O3/c1-19-20-10-14-15-11-17(16-14)9-13(18)8-7-12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84840
PNG
(1-azolyl-4-phenyl-2-butanone, 42)
Show SMILES COOCCc1nnn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C14H18N4O3/c1-20-21-10-9-14-15-17-18(16-14)11-13(19)8-7-12-5-3-2-4-6-12/h2-6H,7-11H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84861
PNG
(1-azolyl-4-phenyl-2-butanone, 63)
Show SMILES OC(CCc1ccccc1)Cn1cnc(c1-c1ccccc1)-c1ccccc1 |w:1.0|
Show InChI InChI=1S/C25H24N2O/c28-23(17-16-20-10-4-1-5-11-20)18-27-19-26-24(21-12-6-2-7-13-21)25(27)22-14-8-3-9-15-22/h1-15,19,23,28H,16-18H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84824
PNG
(1-azolyl-4-phenyl-2-butanone, 26)
Show SMILES ON(O)c1cn(CC(=O)CCc2ccccc2)cn1
Show InChI InChI=1S/C13H15N3O3/c17-12(7-6-11-4-2-1-3-5-11)8-15-9-13(14-10-15)16(18)19/h1-5,9-10,18-19H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84833
PNG
(1-azolyl-4-phenyl-2-butanone, 35)
Show SMILES CSc1ncnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C13H15N3OS/c1-18-13-14-10-15-16(13)9-12(17)8-7-11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84839
PNG
(1-azolyl-4-phenyl-2-butanone, 41)
Show SMILES CSc1nnn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C12H14N4OS/c1-18-12-13-15-16(14-12)9-11(17)8-7-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84843
PNG
(1-azolyl-4-phenyl-2-butanone, 45)
Show SMILES COOSc1ncn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C13H15N3O3S/c1-18-19-20-13-14-10-16(15-13)9-12(17)8-7-11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84839
PNG
(1-azolyl-4-phenyl-2-butanone, 41)
Show SMILES CSc1nnn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C12H14N4OS/c1-18-12-13-15-16(14-12)9-11(17)8-7-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84849
PNG
(1-azolyl-4-phenyl-2-butanone, 51)
Show SMILES C(CC1(Cn2ccnn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C14H17N3O2/c1-2-4-13(5-3-1)6-7-14(18-10-11-19-14)12-17-9-8-15-16-17/h1-5,8-9H,6-7,10-12H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84803
PNG
(1-azolyl-4-phenyl-2-butanone, 5)
Show SMILES O=C(CCc1ccccc1)Cn1cccn1
Show InChI InChI=1S/C13H14N2O/c16-13(11-15-10-4-9-14-15)8-7-12-5-2-1-3-6-12/h1-6,9-10H,7-8,11H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84806
PNG
(1-azolyl-4-phenyl-2-butanone, 8)
Show SMILES O=C(CCc1ccccc1)Cn1ccnn1
Show InChI InChI=1S/C12H13N3O/c16-12(10-15-9-8-13-14-15)7-6-11-4-2-1-3-5-11/h1-5,8-9H,6-7,10H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84807
PNG
(1-azolyl-4-phenyl-2-butanone, 9)
Show SMILES O=C(CCc1ccccc1)Cn1nccn1
Show InChI InChI=1S/C12H13N3O/c16-12(10-15-13-8-9-14-15)7-6-11-4-2-1-3-5-11/h1-5,8-9H,6-7,10H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84811
PNG
(1-azolyl-4-phenyl-2-butanone, 13)
Show SMILES Cn1[n+](CC(=O)CCc2ccccc2)nc2ccccc12
Show InChI InChI=1S/C17H18N3O/c1-19-17-10-6-5-9-16(17)18-20(19)13-15(21)12-11-14-7-3-2-4-8-14/h2-10H,11-13H2,1H3/q+1
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84814
PNG
(1-azolyl-4-phenyl-2-butanone, 16)
Show SMILES O=C(CCc1ccccc1)Cn1ccnc1-c1ccccc1
Show InChI InChI=1S/C19H18N2O/c22-18(12-11-16-7-3-1-4-8-16)15-21-14-13-20-19(21)17-9-5-2-6-10-17/h1-10,13-14H,11-12,15H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84825
PNG
(1-azolyl-4-phenyl-2-butanone, 27)
Show SMILES COOCc1cn(CC(=O)CCc2ccccc2)cn1
Show InChI InChI=1S/C15H18N2O3/c1-19-20-11-14-9-17(12-16-14)10-15(18)8-7-13-5-3-2-4-6-13/h2-6,9,12H,7-8,10-11H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84828
PNG
(1-azolyl-4-phenyl-2-butanone, 30)
Show SMILES COOCc1ncn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C14H17N3O3/c1-19-20-10-14-15-11-17(16-14)9-13(18)8-7-12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84838
PNG
(1-azolyl-4-phenyl-2-butanone, 40)
Show SMILES O=C(CCc1ccccc1)Cn1nnnc1-c1ccccc1
Show InChI InChI=1S/C17H16N4O/c22-16(12-11-14-7-3-1-4-8-14)13-21-17(18-19-20-21)15-9-5-2-6-10-15/h1-10H,11-13H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84842
PNG
(1-azolyl-4-phenyl-2-butanone, 44)
Show SMILES COOSc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H16N2O3S/c1-18-19-20-14-15-9-10-16(14)11-13(17)8-7-12-5-3-2-4-6-12/h2-6,9-10H,7-8,11H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84851
PNG
(1-azolyl-4-phenyl-2-butanone, 53)
Show SMILES C(CC1(Cn2cnnn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C13H16N4O2/c1-2-4-12(5-3-1)6-7-13(18-8-9-19-13)10-17-11-14-15-16-17/h1-5,11H,6-10H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84810
PNG
(1-azolyl-4-phenyl-2-butanone, 12)
Show SMILES Cn1c(CC(=O)CCc2ccccc2)nc2ccccc12
Show InChI InChI=1S/C18H18N2O/c1-20-17-10-6-5-9-16(17)19-18(20)13-15(21)12-11-14-7-3-2-4-8-14/h2-10H,11-13H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84813
PNG
(1-azolyl-4-phenyl-2-butanone, 15)
Show SMILES Cc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H16N2O/c1-12-15-9-10-16(12)11-14(17)8-7-13-5-3-2-4-6-13/h2-6,9-10H,7-8,11H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84816
PNG
(1-azolyl-4-phenyl-2-butanone, 18 | 1-azolyl-4-phen...)
Show SMILES COOCc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C15H18N2O3/c1-19-20-12-15-16-9-10-17(15)11-14(18)8-7-13-5-3-2-4-6-13/h2-6,9-10H,7-8,11-12H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84821
PNG
(1-azolyl-4-phenyl-2-butanone, 23)
Show SMILES NCc1ncn(CC(=O)CCc2ccccc2)c1CN
Show InChI InChI=1S/C15H20N4O/c16-8-14-15(9-17)19(11-18-14)10-13(20)7-6-12-4-2-1-3-5-12/h1-5,11H,6-10,16-17H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84824
PNG
(1-azolyl-4-phenyl-2-butanone, 26)
Show SMILES ON(O)c1cn(CC(=O)CCc2ccccc2)cn1
Show InChI InChI=1S/C13H15N3O3/c17-12(7-6-11-4-2-1-3-5-11)8-15-9-13(14-10-15)16(18)19/h1-5,9-10,18-19H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84829
PNG
(1-azolyl-4-phenyl-2-butanone, 31)
Show SMILES CSc1ncn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C13H15N3OS/c1-18-13-14-10-16(15-13)9-12(17)8-7-11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84813
PNG
(1-azolyl-4-phenyl-2-butanone, 15)
Show SMILES Cc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H16N2O/c1-12-15-9-10-16(12)11-14(17)8-7-13-5-3-2-4-6-13/h2-6,9-10H,7-8,11H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84818
PNG
(1-azolyl-4-phenyl-2-butanone, 20)
Show SMILES Clc1ncn(CC(=O)CCc2ccccc2)c1Cl
Show InChI InChI=1S/C13H12Cl2N2O/c14-12-13(15)17(9-16-12)8-11(18)7-6-10-4-2-1-3-5-10/h1-5,9H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84820
PNG
(1-azolyl-4-phenyl-2-butanone, 22)
Show SMILES COOCc1ncn(CC(=O)CCc2ccccc2)c1COOC
Show InChI InChI=1S/C17H22N2O5/c1-21-23-11-16-17(12-24-22-2)19(13-18-16)10-15(20)9-8-14-6-4-3-5-7-14/h3-7,13H,8-12H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84844
PNG
(1-azolyl-4-phenyl-2-butanone, 46)
Show SMILES COOSc1ncnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C13H15N3O3S/c1-18-19-20-13-14-10-15-16(13)9-12(17)8-7-11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84849
PNG
(1-azolyl-4-phenyl-2-butanone, 51)
Show SMILES C(CC1(Cn2ccnn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C14H17N3O2/c1-2-4-13(5-3-1)6-7-14(18-10-11-19-14)12-17-9-8-15-16-17/h1-5,8-9H,6-7,10-12H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84854
PNG
(1-azolyl-4-phenyl-2-butanone, 56)
Show SMILES C(CC1(Cn2cnc(c2-c2ccccc2)-c2ccccc2)OCCO1)c1ccccc1
Show InChI InChI=1S/C27H26N2O2/c1-4-10-22(11-5-1)16-17-27(30-18-19-31-27)20-29-21-28-25(23-12-6-2-7-13-23)26(29)24-14-8-3-9-15-24/h1-15,21H,16-20H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84858
PNG
(1-azolyl-4-phenyl-2-butanone, 60)
Show SMILES OC(CCc1ccccc1)Cn1cnnn1 |w:1.0|
Show InChI InChI=1S/C11H14N4O/c16-11(8-15-9-12-13-14-15)7-6-10-4-2-1-3-5-10/h1-5,9,11,16H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84811
PNG
(1-azolyl-4-phenyl-2-butanone, 13)
Show SMILES Cn1[n+](CC(=O)CCc2ccccc2)nc2ccccc12
Show InChI InChI=1S/C17H18N3O/c1-19-17-10-6-5-9-16(17)18-20(19)13-15(21)12-11-14-7-3-2-4-8-14/h2-10H,11-13H2,1H3/q+1
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84816
PNG
(1-azolyl-4-phenyl-2-butanone, 18 | 1-azolyl-4-phen...)
Show SMILES COOCc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C15H18N2O3/c1-19-20-12-15-16-9-10-17(15)11-14(18)8-7-13-5-3-2-4-6-13/h2-6,9-10H,7-8,11-12H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84836
PNG
(1-azolyl-4-phenyl-2-butanone, 38)
Show SMILES CSc1nnnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C12H14N4OS/c1-18-12-13-14-15-16(12)9-11(17)8-7-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84837
PNG
(1-azolyl-4-phenyl-2-butanone, 39)
Show SMILES CC(C)OCCc1nnnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C15H21N4O3/c1-22(2)21-11-10-15-16-17-18-19(15)12-14(20)9-8-13-6-4-3-5-7-13/h3-7H,8-12H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84841
PNG
(1-azolyl-4-phenyl-2-butanone, 43)
Show SMILES O=C(CCc1ccccc1)Cn1nnc(n1)-c1ccccc1
Show InChI InChI=1S/C17H16N4O/c22-16(12-11-14-7-3-1-4-8-14)13-21-19-17(18-20-21)15-9-5-2-6-10-15/h1-10H,11-13H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84842
PNG
(1-azolyl-4-phenyl-2-butanone, 44)
Show SMILES COOSc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H16N2O3S/c1-18-19-20-14-15-9-10-16(14)11-13(17)8-7-12-5-3-2-4-6-12/h2-6,9-10H,7-8,11H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84845
PNG
(1-azolyl-4-phenyl-2-butanone, 47)
Show SMILES COOSc1nnnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C12H14N4O3S/c1-18-19-20-12-13-14-15-16(12)9-11(17)8-7-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84850
PNG
(1-azolyl-4-phenyl-2-butanone, 52)
Show SMILES C(CC1(Cn2nccn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C14H17N3O2/c1-2-4-13(5-3-1)6-7-14(18-10-11-19-14)12-17-15-8-9-16-17/h1-5,8-9H,6-7,10-12H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84812
PNG
(1-azolyl-4-phenyl-2-butanone, 14)
Show SMILES O=C(CCc1ccccc1)Cn1nc2ccccc2n1
Show InChI InChI=1S/C16H15N3O/c20-14(11-10-13-6-2-1-3-7-13)12-19-17-15-8-4-5-9-16(15)18-19/h1-9H,10-12H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84821
PNG
(1-azolyl-4-phenyl-2-butanone, 23)
Show SMILES NCc1ncn(CC(=O)CCc2ccccc2)c1CN
Show InChI InChI=1S/C15H20N4O/c16-8-14-15(9-17)19(11-18-14)10-13(20)7-6-12-4-2-1-3-5-12/h1-5,11H,6-10,16-17H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84852
PNG
(1-azolyl-4-phenyl-2-butanone, 54)
Show SMILES C(CC1(Cn2ncnn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C13H16N4O2/c1-2-4-12(5-3-1)6-7-13(18-8-9-19-13)10-17-15-11-14-16-17/h1-5,11H,6-10H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84860
PNG
(1-azolyl-4-phenyl-2-butanone, 62)
Show SMILES OC(CCc1ccccc1)Cn1cnc(c1)-c1ccccc1 |w:1.0|
Show InChI InChI=1S/C19H20N2O/c22-18(12-11-16-7-3-1-4-8-16)13-21-14-19(20-15-21)17-9-5-2-6-10-17/h1-10,14-15,18,22H,11-13H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84823
PNG
(1-azolyl-4-phenyl-2-butanone, 25)
Show SMILES Brc1cn(CC(=O)CCc2ccccc2)cn1
Show InChI InChI=1S/C13H13BrN2O/c14-13-9-16(10-15-13)8-12(17)7-6-11-4-2-1-3-5-11/h1-5,9-10H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84815
PNG
(1-azolyl-4-phenyl-2-butanone, 17)
Show SMILES SCc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H16N2OS/c17-13(7-6-12-4-2-1-3-5-12)10-16-9-8-15-14(16)11-18/h1-5,8-9,18H,6-7,10-11H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84835
PNG
(1-azolyl-4-phenyl-2-butanone, 37)
Show SMILES O=C(CCc1ccccc1)Cn1nc(nc1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C24H21N3O/c28-22(17-16-19-10-4-1-5-11-19)18-27-24(21-14-8-3-9-15-21)25-23(26-27)20-12-6-2-7-13-20/h1-15H,16-18H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84840
PNG
(1-azolyl-4-phenyl-2-butanone, 42)
Show SMILES COOCCc1nnn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C14H18N4O3/c1-20-21-10-9-14-15-17-18(16-14)11-13(19)8-7-12-5-3-2-4-6-12/h2-6H,7-11H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84841
PNG
(1-azolyl-4-phenyl-2-butanone, 43)
Show SMILES O=C(CCc1ccccc1)Cn1nnc(n1)-c1ccccc1
Show InChI InChI=1S/C17H16N4O/c22-16(12-11-14-7-3-1-4-8-14)13-21-19-17(18-20-21)15-9-5-2-6-10-15/h1-10H,11-13H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84845
PNG
(1-azolyl-4-phenyl-2-butanone, 47)
Show SMILES COOSc1nnnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C12H14N4O3S/c1-18-19-20-12-13-14-15-16(12)9-11(17)8-7-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84853
PNG
(1-azolyl-4-phenyl-2-butanone, 55)
Show SMILES C(CC1(Cn2cnc(c2)-c2ccccc2)OCCO1)c1ccccc1
Show InChI InChI=1S/C21H22N2O2/c1-3-7-18(8-4-1)11-12-21(24-13-14-25-21)16-23-15-20(22-17-23)19-9-5-2-6-10-19/h1-10,15,17H,11-14,16H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84859
PNG
(1-azolyl-4-phenyl-2-butanone, 61)
Show SMILES OC(CCc1ccccc1)Cn1ncnn1 |w:1.0|
Show InChI InChI=1S/C11H14N4O/c16-11(8-15-13-9-12-14-15)7-6-10-4-2-1-3-5-10/h1-5,9,11,16H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84861
PNG
(1-azolyl-4-phenyl-2-butanone, 63)
Show SMILES OC(CCc1ccccc1)Cn1cnc(c1-c1ccccc1)-c1ccccc1 |w:1.0|
Show InChI InChI=1S/C25H24N2O/c28-23(17-16-20-10-4-1-5-11-20)18-27-19-26-24(21-12-6-2-7-13-21)25(27)22-14-8-3-9-15-22/h1-15,19,23,28H,16-18H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84818
PNG
(1-azolyl-4-phenyl-2-butanone, 20)
Show SMILES Clc1ncn(CC(=O)CCc2ccccc2)c1Cl
Show InChI InChI=1S/C13H12Cl2N2O/c14-12-13(15)17(9-16-12)8-11(18)7-6-10-4-2-1-3-5-10/h1-5,9H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84820
PNG
(1-azolyl-4-phenyl-2-butanone, 22)
Show SMILES COOCc1ncn(CC(=O)CCc2ccccc2)c1COOC
Show InChI InChI=1S/C17H22N2O5/c1-21-23-11-16-17(12-24-22-2)19(13-18-16)10-15(20)9-8-14-6-4-3-5-7-14/h3-7,13H,8-12H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84833
PNG
(1-azolyl-4-phenyl-2-butanone, 35)
Show SMILES CSc1ncnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C13H15N3OS/c1-18-13-14-10-15-16(13)9-12(17)8-7-11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84838
PNG
(1-azolyl-4-phenyl-2-butanone, 40)
Show SMILES O=C(CCc1ccccc1)Cn1nnnc1-c1ccccc1
Show InChI InChI=1S/C17H16N4O/c22-16(12-11-14-7-3-1-4-8-14)13-21-17(18-19-20-21)15-9-5-2-6-10-15/h1-10H,11-13H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84816
PNG
(1-azolyl-4-phenyl-2-butanone, 18 | 1-azolyl-4-phen...)
Show SMILES COOCc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C15H18N2O3/c1-19-20-12-15-16-9-10-17(15)11-14(18)8-7-13-5-3-2-4-6-13/h2-6,9-10H,7-8,11-12H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84816
PNG
(1-azolyl-4-phenyl-2-butanone, 18 | 1-azolyl-4-phen...)
Show SMILES COOCc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C15H18N2O3/c1-19-20-12-15-16-9-10-17(15)11-14(18)8-7-13-5-3-2-4-6-13/h2-6,9-10H,7-8,11-12H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84830
PNG
(1-azolyl-4-phenyl-2-butanone, 32)
Show SMILES ON(O)c1ncn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C12H14N4O3/c17-11(7-6-10-4-2-1-3-5-10)8-15-9-13-12(14-15)16(18)19/h1-5,9,18-19H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84836
PNG
(1-azolyl-4-phenyl-2-butanone, 38)
Show SMILES CSc1nnnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C12H14N4OS/c1-18-12-13-14-15-16(12)9-11(17)8-7-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84837
PNG
(1-azolyl-4-phenyl-2-butanone, 39)
Show SMILES CC(C)OCCc1nnnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C15H21N4O3/c1-22(2)21-11-10-15-16-17-18-19(15)12-14(20)9-8-13-6-4-3-5-7-13/h3-7H,8-12H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84812
PNG
(1-azolyl-4-phenyl-2-butanone, 14)
Show SMILES O=C(CCc1ccccc1)Cn1nc2ccccc2n1
Show InChI InChI=1S/C16H15N3O/c20-14(11-10-13-6-2-1-3-7-13)12-19-17-15-8-4-5-9-16(15)18-19/h1-9H,10-12H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84815
PNG
(1-azolyl-4-phenyl-2-butanone, 17)
Show SMILES SCc1nccn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H16N2OS/c17-13(7-6-12-4-2-1-3-5-12)10-16-9-8-15-14(16)11-18/h1-5,8-9,18H,6-7,10-11H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84830
PNG
(1-azolyl-4-phenyl-2-butanone, 32)
Show SMILES ON(O)c1ncn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C12H14N4O3/c17-11(7-6-10-4-2-1-3-5-10)8-15-9-13-12(14-15)16(18)19/h1-5,9,18-19H,6-8H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84832
PNG
(1-azolyl-4-phenyl-2-butanone, 34)
Show SMILES COOCc1ncnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H17N3O3/c1-19-20-10-14-15-11-16-17(14)9-13(18)8-7-12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84835
PNG
(1-azolyl-4-phenyl-2-butanone, 37)
Show SMILES O=C(CCc1ccccc1)Cn1nc(nc1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C24H21N3O/c28-22(17-16-19-10-4-1-5-11-19)18-27-24(21-14-8-3-9-15-21)25-23(26-27)20-12-6-2-7-13-20/h1-15H,16-18H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84844
PNG
(1-azolyl-4-phenyl-2-butanone, 46)
Show SMILES COOSc1ncnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C13H15N3O3S/c1-18-19-20-13-14-10-15-16(13)9-12(17)8-7-11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84846
PNG
(1-azolyl-4-phenyl-2-butanone, 48)
Show SMILES COOSc1nnn(CC(=O)CCc2ccccc2)n1
Show InChI InChI=1S/C12H14N4O3S/c1-18-19-20-12-13-15-16(14-12)9-11(17)8-7-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84819
PNG
(1-azolyl-4-phenyl-2-butanone, 21)
Show SMILES O=C(CCc1ccccc1)Cn1cnc(c1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C25H22N2O/c28-23(17-16-20-10-4-1-5-11-20)18-27-19-26-24(21-12-6-2-7-13-21)25(27)22-14-8-3-9-15-22/h1-15,19H,16-18H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84826
PNG
(1-azolyl-4-phenyl-2-butanone, 28)
Show SMILES Brc1cncn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C13H13BrN2O/c14-13-8-15-10-16(13)9-12(17)7-6-11-4-2-1-3-5-11/h1-5,8,10H,6-7,9H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84827
PNG
(1-azolyl-4-phenyl-2-butanone, 29)
Show SMILES COOCc1cncn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C15H18N2O3/c1-19-20-11-14-9-16-12-17(14)10-15(18)8-7-13-5-3-2-4-6-13/h2-6,9,12H,7-8,10-11H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84832
PNG
(1-azolyl-4-phenyl-2-butanone, 34)
Show SMILES COOCc1ncnn1CC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H17N3O3/c1-19-20-10-14-15-11-16-17(14)9-13(18)8-7-12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84848
PNG
(1-azolyl-4-phenyl-2-butanone, 50)
Show SMILES C(CC1(Cn2cncn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C14H17N3O2/c1-2-4-13(5-3-1)6-7-14(18-8-9-19-14)10-17-12-15-11-16-17/h1-5,11-12H,6-10H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84850
PNG
(1-azolyl-4-phenyl-2-butanone, 52)
Show SMILES C(CC1(Cn2nccn2)OCCO1)c1ccccc1
Show InChI InChI=1S/C14H17N3O2/c1-2-4-13(5-3-1)6-7-14(18-10-11-19-14)12-17-15-8-9-16-17/h1-5,8-9H,6-7,10-12H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM84857
PNG
(1-azolyl-4-phenyl-2-butanone, 59)
Show SMILES OC(CCc1ccccc1)Cn1ccnn1 |w:1.0|
Show InChI InChI=1S/C12H15N3O/c16-12(10-15-9-8-13-14-15)7-6-11-4-2-1-3-5-11/h1-5,8-9,12,16H,6-7,10H2
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n/an/a>1.00E+5n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84805
PNG
(1-azolyl-4-phenyl-2-butanone, 7)
Show SMILES O=C(CCc1ccccc1)Cn1cncn1
Show InChI InChI=1S/C12H13N3O/c16-12(8-15-10-13-9-14-15)7-6-11-4-2-1-3-5-11/h1-5,9-10H,6-8H2
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n/an/a 2.50E+6n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84804
PNG
(1-azolyl-4-phenyl-2-butanone, 6a | CHEMBL536514)
Show SMILES O=C(CCc1ccccc1)Cn1ccnc1
Show InChI InChI=1S/C13H14N2O/c16-13(10-15-9-8-14-11-15)7-6-12-4-2-1-3-5-12/h1-5,8-9,11H,6-7,10H2
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n/an/a 4.00E+6n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84808
PNG
(1-azolyl-4-phenyl-2-butanone, 10 | 1-azolyl-4-phen...)
Show SMILES O=C(CCc1ccccc1)Cn1ncnn1
Show InChI InChI=1S/C11H12N4O/c16-11(8-15-13-9-12-14-15)7-6-10-4-2-1-3-5-10/h1-5,9H,6-8H2
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n/an/a 9.60E+6n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84806
PNG
(1-azolyl-4-phenyl-2-butanone, 8)
Show SMILES O=C(CCc1ccccc1)Cn1ccnn1
Show InChI InChI=1S/C12H13N3O/c16-12(10-15-9-8-13-14-15)7-6-11-4-2-1-3-5-11/h1-5,8-9H,6-7,10H2
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n/an/a 8.90E+7n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84807
PNG
(1-azolyl-4-phenyl-2-butanone, 9)
Show SMILES O=C(CCc1ccccc1)Cn1nccn1
Show InChI InChI=1S/C12H13N3O/c16-12(10-15-13-8-9-14-15)7-6-11-4-2-1-3-5-11/h1-5,8-9H,6-7,10H2
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n/an/a>1.00E+8n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM84803
PNG
(1-azolyl-4-phenyl-2-butanone, 5)
Show SMILES O=C(CCc1ccccc1)Cn1cccn1
Show InChI InChI=1S/C13H14N2O/c16-13(11-15-10-4-9-14-15)8-7-12-5-2-1-3-6-12/h1-6,9-10H,7-8,11H2
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n/an/a>1.00E+8n/an/an/an/a7.425



Queen's University



Assay Description
Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...


Chem Biol Drug Des 75: 68-90 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00909.x
BindingDB Entry DOI: 10.7270/Q25B0101
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%