Found 42 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM5446
(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)Show InChI InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
MMDB
PDB
Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308926
(4-(Bis(2-chloroethyl)amino)-N-(4-methoxyphenyl)ben...)Show InChI InChI=1S/C18H20Cl2N2O2/c1-24-17-8-4-15(5-9-17)21-18(23)14-2-6-16(7-3-14)22(12-10-19)13-11-20/h2-9H,10-13H2,1H3,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308944
(4-(Bis(2-chloroethyl)amino)-N-(1-naphthyl)benzamid...)Show InChI InChI=1S/C21H20Cl2N2O/c22-12-14-25(15-13-23)18-10-8-17(9-11-18)21(26)24-20-7-3-5-16-4-1-2-6-19(16)20/h1-11H,12-15H2,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM5446
(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)Show InChI InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308944
(4-(Bis(2-chloroethyl)amino)-N-(1-naphthyl)benzamid...)Show InChI InChI=1S/C21H20Cl2N2O/c22-12-14-25(15-13-23)18-10-8-17(9-11-18)21(26)24-20-7-3-5-16-4-1-2-6-19(16)20/h1-11H,12-15H2,(H,24,26) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308926
(4-(Bis(2-chloroethyl)amino)-N-(4-methoxyphenyl)ben...)Show InChI InChI=1S/C18H20Cl2N2O2/c1-24-17-8-4-15(5-9-17)21-18(23)14-2-6-16(7-3-14)22(12-10-19)13-11-20/h2-9H,10-13H2,1H3,(H,21,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308927
(4-(Bis(2-chloroethyl)amino)-N-p-tolylbenzamide | C...)Show InChI InChI=1S/C18H20Cl2N2O/c1-14-2-6-16(7-3-14)21-18(23)15-4-8-17(9-5-15)22(12-10-19)13-11-20/h2-9H,10-13H2,1H3,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308925
(4-(Bis(2-chloroethyl)amino)-N-(4-isopropylphenyl)b...)Show InChI InChI=1S/C20H24Cl2N2O/c1-15(2)16-3-7-18(8-4-16)23-20(25)17-5-9-19(10-6-17)24(13-11-21)14-12-22/h3-10,15H,11-14H2,1-2H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308933
(4-(Bis(2-chloroethyl)amino)-N-(4-bromophenyl)benza...)Show InChI InChI=1S/C17H17BrCl2N2O/c18-14-3-5-15(6-4-14)21-17(23)13-1-7-16(8-2-13)22(11-9-19)12-10-20/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 940 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308932
(4-(Bis(2-chloroethyl)amino)-N-(4-chlorophenyl)benz...)Show InChI InChI=1S/C17H17Cl3N2O/c18-9-11-22(12-10-19)16-7-1-13(2-8-16)17(23)21-15-5-3-14(20)4-6-15/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308931
(4-(Bis(2-chloroethyl)amino)-N-(4-fluorophenyl)benz...)Show InChI InChI=1S/C17H17Cl2FN2O/c18-9-11-22(12-10-19)16-7-1-13(2-8-16)17(23)21-15-5-3-14(20)4-6-15/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308927
(4-(Bis(2-chloroethyl)amino)-N-p-tolylbenzamide | C...)Show InChI InChI=1S/C18H20Cl2N2O/c1-14-2-6-16(7-3-14)21-18(23)15-4-8-17(9-5-15)22(12-10-19)13-11-20/h2-9H,10-13H2,1H3,(H,21,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308925
(4-(Bis(2-chloroethyl)amino)-N-(4-isopropylphenyl)b...)Show InChI InChI=1S/C20H24Cl2N2O/c1-15(2)16-3-7-18(8-4-16)23-20(25)17-5-9-19(10-6-17)24(13-11-21)14-12-22/h3-10,15H,11-14H2,1-2H3,(H,23,25) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308933
(4-(Bis(2-chloroethyl)amino)-N-(4-bromophenyl)benza...)Show InChI InChI=1S/C17H17BrCl2N2O/c18-14-3-5-15(6-4-14)21-17(23)13-1-7-16(8-2-13)22(11-9-19)12-10-20/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308932
(4-(Bis(2-chloroethyl)amino)-N-(4-chlorophenyl)benz...)Show InChI InChI=1S/C17H17Cl3N2O/c18-9-11-22(12-10-19)16-7-1-13(2-8-16)17(23)21-15-5-3-14(20)4-6-15/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308931
(4-(Bis(2-chloroethyl)amino)-N-(4-fluorophenyl)benz...)Show InChI InChI=1S/C17H17Cl2FN2O/c18-9-11-22(12-10-19)16-7-1-13(2-8-16)17(23)21-15-5-3-14(20)4-6-15/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308930
(4-(Bis(2-chloroethyl)amino)-N-(2-bromophenyl)benza...)Show InChI InChI=1S/C17H17BrCl2N2O/c18-15-3-1-2-4-16(15)21-17(23)13-5-7-14(8-6-13)22(11-9-19)12-10-20/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308929
(4-(Bis(2-chloroethyl)amino)-N-(2-chlorophenyl)benz...)Show InChI InChI=1S/C17H17Cl3N2O/c18-9-11-22(12-10-19)14-7-5-13(6-8-14)17(23)21-16-4-2-1-3-15(16)20/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308930
(4-(Bis(2-chloroethyl)amino)-N-(2-bromophenyl)benza...)Show InChI InChI=1S/C17H17BrCl2N2O/c18-15-3-1-2-4-16(15)21-17(23)13-5-7-14(8-6-13)22(11-9-19)12-10-20/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308928
(4-(Bis(2-chloroethyl)amino)-N-(2-fluorophenyl)benz...)Show InChI InChI=1S/C17H17Cl2FN2O/c18-9-11-22(12-10-19)14-7-5-13(6-8-14)17(23)21-16-4-2-1-3-15(16)20/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308929
(4-(Bis(2-chloroethyl)amino)-N-(2-chlorophenyl)benz...)Show InChI InChI=1S/C17H17Cl3N2O/c18-9-11-22(12-10-19)14-7-5-13(6-8-14)17(23)21-16-4-2-1-3-15(16)20/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308937
(4-(Bis(2-chloroethyl)amino)-N-methyl-N-phenylbenza...)Show InChI InChI=1S/C18H20Cl2N2O/c1-21(16-5-3-2-4-6-16)18(23)15-7-9-17(10-8-15)22(13-11-19)14-12-20/h2-10H,11-14H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308928
(4-(Bis(2-chloroethyl)amino)-N-(2-fluorophenyl)benz...)Show InChI InChI=1S/C17H17Cl2FN2O/c18-9-11-22(12-10-19)14-7-5-13(6-8-14)17(23)21-16-4-2-1-3-15(16)20/h1-8H,9-12H2,(H,21,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308943
(CHEMBL589847 | N-Benzyl-4-(bis(2-chloroethyl)amino...)Show InChI InChI=1S/C18H20Cl2N2O/c19-10-12-22(13-11-20)17-8-6-16(7-9-17)18(23)21-14-15-4-2-1-3-5-15/h1-9H,10-14H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308934
(4-(Bis(2-chloroethyl)amino)-N-(4-nitrophenyl)benza...)Show SMILES [O-][N+](=O)c1ccc(NC(=O)c2ccc(cc2)N(CCCl)CCCl)cc1 Show InChI InChI=1S/C17H17Cl2N3O3/c18-9-11-21(12-10-19)15-5-1-13(2-6-15)17(23)20-14-3-7-16(8-4-14)22(24)25/h1-8H,9-12H2,(H,20,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308937
(4-(Bis(2-chloroethyl)amino)-N-methyl-N-phenylbenza...)Show InChI InChI=1S/C18H20Cl2N2O/c1-21(16-5-3-2-4-6-16)18(23)15-7-9-17(10-8-15)22(13-11-19)14-12-20/h2-10H,11-14H2,1H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308938
(4-(Bis(2-chloroethyl)amino)-N-butylbenzamide | CHE...)Show InChI InChI=1S/C15H22Cl2N2O/c1-2-3-10-18-15(20)13-4-6-14(7-5-13)19(11-8-16)12-9-17/h4-7H,2-3,8-12H2,1H3,(H,18,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308943
(CHEMBL589847 | N-Benzyl-4-(bis(2-chloroethyl)amino...)Show InChI InChI=1S/C18H20Cl2N2O/c19-10-12-22(13-11-20)17-8-6-16(7-9-17)18(23)21-14-15-4-2-1-3-5-15/h1-9H,10-14H2,(H,21,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308934
(4-(Bis(2-chloroethyl)amino)-N-(4-nitrophenyl)benza...)Show SMILES [O-][N+](=O)c1ccc(NC(=O)c2ccc(cc2)N(CCCl)CCCl)cc1 Show InChI InChI=1S/C17H17Cl2N3O3/c18-9-11-21(12-10-19)15-5-1-13(2-6-15)17(23)20-14-3-7-16(8-4-14)22(24)25/h1-8H,9-12H2,(H,20,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308935
(4-(Bis(2-chloroethyl)amino)-N,N-dipropylbenzamide ...)Show InChI InChI=1S/C17H26Cl2N2O/c1-3-11-21(12-4-2)17(22)15-5-7-16(8-6-15)20(13-9-18)14-10-19/h5-8H,3-4,9-14H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308938
(4-(Bis(2-chloroethyl)amino)-N-butylbenzamide | CHE...)Show InChI InChI=1S/C15H22Cl2N2O/c1-2-3-10-18-15(20)13-4-6-14(7-5-13)19(11-8-16)12-9-17/h4-7H,2-3,8-12H2,1H3,(H,18,20) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308936
(4-(Bis(2-chloroethyl)amino)-N,N-dibutylbenzamide |...)Show InChI InChI=1S/C19H30Cl2N2O/c1-3-5-13-23(14-6-4-2)19(24)17-7-9-18(10-8-17)22(15-11-20)16-12-21/h7-10H,3-6,11-16H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308939
(4-(Bis(2-chloroethyl)amino)-N-tert-butylbenzamide ...)Show InChI InChI=1S/C15H22Cl2N2O/c1-15(2,3)18-14(20)12-4-6-13(7-5-12)19(10-8-16)11-9-17/h4-7H,8-11H2,1-3H3,(H,18,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308941
(4-(Bis(2-chloroethyl)amino)-N-cyclopentylbenzamide...)Show InChI InChI=1S/C16H22Cl2N2O/c17-9-11-20(12-10-18)15-7-5-13(6-8-15)16(21)19-14-3-1-2-4-14/h5-8,14H,1-4,9-12H2,(H,19,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308935
(4-(Bis(2-chloroethyl)amino)-N,N-dipropylbenzamide ...)Show InChI InChI=1S/C17H26Cl2N2O/c1-3-11-21(12-4-2)17(22)15-5-7-16(8-6-15)20(13-9-18)14-10-19/h5-8H,3-4,9-14H2,1-2H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308936
(4-(Bis(2-chloroethyl)amino)-N,N-dibutylbenzamide |...)Show InChI InChI=1S/C19H30Cl2N2O/c1-3-5-13-23(14-6-4-2)19(24)17-7-9-18(10-8-17)22(15-11-20)16-12-21/h7-10H,3-6,11-16H2,1-2H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308939
(4-(Bis(2-chloroethyl)amino)-N-tert-butylbenzamide ...)Show InChI InChI=1S/C15H22Cl2N2O/c1-15(2,3)18-14(20)12-4-6-13(7-5-12)19(10-8-16)11-9-17/h4-7H,8-11H2,1-3H3,(H,18,20) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308941
(4-(Bis(2-chloroethyl)amino)-N-cyclopentylbenzamide...)Show InChI InChI=1S/C16H22Cl2N2O/c17-9-11-20(12-10-18)15-7-5-13(6-8-15)16(21)19-14-3-1-2-4-14/h5-8,14H,1-4,9-12H2,(H,19,21) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308940
(4-(Bis(2-chloroethyl)amino)-N-dodecylbenzamide | C...)Show InChI InChI=1S/C23H38Cl2N2O/c1-2-3-4-5-6-7-8-9-10-11-18-26-23(28)21-12-14-22(15-13-21)27(19-16-24)20-17-25/h12-15H,2-11,16-20H2,1H3,(H,26,28) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308942
(4-(Bis(2-chloroethyl)amino)-N-(3-morpholinopropyl)...)Show InChI InChI=1S/C18H27Cl2N3O2/c19-6-10-23(11-7-20)17-4-2-16(3-5-17)18(24)21-8-1-9-22-12-14-25-15-13-22/h2-5H,1,6-15H2,(H,21,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50308940
(4-(Bis(2-chloroethyl)amino)-N-dodecylbenzamide | C...)Show InChI InChI=1S/C23H38Cl2N2O/c1-2-3-4-5-6-7-8-9-10-11-18-26-23(28)21-12-14-22(15-13-21)27(19-16-24)20-17-25/h12-15H,2-11,16-20H2,1H3,(H,26,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50308942
(4-(Bis(2-chloroethyl)amino)-N-(3-morpholinopropyl)...)Show InChI InChI=1S/C18H27Cl2N3O2/c19-6-10-23(11-7-20)17-4-2-16(3-5-17)18(24)21-8-1-9-22-12-14-25-15-13-22/h2-5H,1,6-15H2,(H,21,24) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA |
Bioorg Med Chem 18: 880-6 (2010)
Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N |
More data for this
Ligand-Target Pair | |
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