Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50312536 (CHEMBL1076889 | sodiumperfluorohexanesulfonamide) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 122 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut des Biomol£cules Max Mousseron UMR CNRS 5247 Universit£ de Montpellier I et de Montpellier II Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 assessed as conversion of 4-nitrophenyl acetate to 4-nitrophnolate after 5 mins | Eur J Med Chem 45: 1225-9 (2010) Article DOI: 10.1016/j.ejmech.2009.11.052 BindingDB Entry DOI: 10.7270/Q23778V4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 152 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut des Biomol£cules Max Mousseron UMR CNRS 5247 Universit£ de Montpellier I et de Montpellier II Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 assessed as conversion of 4-nitrophenyl acetate to 4-nitrophnolate after 5 mins | Eur J Med Chem 45: 1225-9 (2010) Article DOI: 10.1016/j.ejmech.2009.11.052 BindingDB Entry DOI: 10.7270/Q23778V4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |