Affinity Data by PubMed id=20045339

PubMed code 20045339

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310078 ((R/S)-1-(3-(6-Methoxynaphthalen-2-yl)butyl)piperid...) Show SMILES COc1ccc2cc(ccc2c1)C(C)CCN1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310077 ((R/S)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-meth...) Show SMILES COc1ccc2cc(ccc2c1)C(C)CCN(C)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310074 ((R/S)-4-(benzyl(methyl)amino)-2-(biphenyl-4-yl)but...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50198062 ((R/S)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbutan-1-a...) Show SMILES CC(CCN(C)Cc1ccccc1)c1ccc(cc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50198065 (4(E)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbut-2-en-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310076 ((E)-1-(3-(6-Methoxynaphthalen-2-yl)but-2-enyl)pipe...) Show SMILES COc1ccc2cc(ccc2c1)C(\C)=C\CN1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310072 ((R/S)-4-(Benzyl(methyl)amino)-2-(6-methoxynaphthal...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310073 ((R/S)-2-(6-Methoxynaphthalen-2-yl)-4-(piperidin-1-...) Show SMILES COc1ccc2cc(ccc2c1)C(C)(O)CCN1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310075 ((E)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50198055 ((R/S)-3-(6-Methoxynaphthalen-2-yl)-N,N-dimethylbut...) Show SMILES COc1ccc2cc(ccc2c1)C(C)CCN(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50198066 ((E)-3-(6-Methoxynaphthalen-2-yl)-N,N-dimethylbut-2...) Show SMILES COc1ccc2cc(ccc2c1)C(\C)=C\CN(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310071 ((R/S)-4-(Dimethylamino)-2-(6-methoxynaphthalen-2-y...) Show SMILES COc1ccc2cc(ccc2c1)C(C)(O)CCN(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50310072 ((R/S)-4-(Benzyl(methyl)amino)-2-(6-methoxynaphthal...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat brain homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50310077 ((R/S)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-meth...) Show SMILES COc1ccc2cc(ccc2c1)C(C)CCN(C)Cc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	171	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat brain homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50198062 ((R/S)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbutan-1-a...) Show SMILES CC(CCN(C)Cc1ccccc1)c1ccc(cc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	248	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu-type opioid receptor in guinea pig brain homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50310077 ((R/S)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-meth...) Show SMILES COc1ccc2cc(ccc2c1)C(C)CCN(C)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	841	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-U-69593 from kappa-type opioid receptor in guinea pig brain homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%