Found 9 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50310096
((7,12-dihydro-3-methoxytetraphen-12-yl)methanamine...)Show InChI InChI=1S/C20H19NO/c1-22-16-8-9-18-14(11-16)6-7-15-10-13-4-2-3-5-17(13)19(12-21)20(15)18/h2-9,11,19H,10,12,21H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ketanserin from human cloned 5HT2A receptor |
Bioorg Med Chem Lett 20: 935-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.064
BindingDB Entry DOI: 10.7270/Q2F47P8J |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50310098
(CHEMBL609328 | N-((9,10-Dihydroanthracen-9-yl)meth...)Show InChI InChI=1S/C24H25N/c1-2-9-19(10-3-1)11-8-16-25-18-24-22-14-6-4-12-20(22)17-21-13-5-7-15-23(21)24/h1-7,9-10,12-15,24-25H,8,11,16-18H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 223 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ketanserin from human cloned 5HT2A receptor |
Bioorg Med Chem Lett 20: 935-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.064
BindingDB Entry DOI: 10.7270/Q2F47P8J |
More data for this
Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50310097
(CHEMBL590241 | N-((9,10-Dihydroanthracen-9-yl)meth...)Show InChI InChI=1S/C23H23N/c1-2-8-18(9-3-1)14-15-24-17-23-21-12-6-4-10-19(21)16-20-11-5-7-13-22(20)23/h1-13,23-24H,14-17H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 242 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description
Displacement of [3H]Pyrilamine from human cloned histamine H1 receptor |
Bioorg Med Chem Lett 20: 935-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.064
BindingDB Entry DOI: 10.7270/Q2F47P8J |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50310099
(CHEMBL597528 | N-((9,10-Dihydroanthracen-9-yl)meth...)Show InChI InChI=1S/C25H27N/c1-2-10-20(11-3-1)12-8-9-17-26-19-25-23-15-6-4-13-21(23)18-22-14-5-7-16-24(22)25/h1-7,10-11,13-16,25-26H,8-9,12,17-19H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 365 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ketanserin from human cloned 5HT2A receptor |
Bioorg Med Chem Lett 20: 935-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.064
BindingDB Entry DOI: 10.7270/Q2F47P8J |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50310097
(CHEMBL590241 | N-((9,10-Dihydroanthracen-9-yl)meth...)Show InChI InChI=1S/C23H23N/c1-2-8-18(9-3-1)14-15-24-17-23-21-12-6-4-10-19(21)16-20-11-5-7-13-22(20)23/h1-13,23-24H,14-17H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ketanserin from human cloned 5HT2A receptor |
Bioorg Med Chem Lett 20: 935-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.064
BindingDB Entry DOI: 10.7270/Q2F47P8J |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50097644
(9-(N-benzylaminomethyl)-9,10-dihydroanthracene | B...)Show InChI InChI=1S/C22H21N/c1-2-8-17(9-3-1)15-23-16-22-20-12-6-4-10-18(20)14-19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 721 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ketanserin from human cloned 5HT2A receptor |
Bioorg Med Chem Lett 20: 935-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.064
BindingDB Entry DOI: 10.7270/Q2F47P8J |
More data for this
Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50310098
(CHEMBL609328 | N-((9,10-Dihydroanthracen-9-yl)meth...)Show InChI InChI=1S/C24H25N/c1-2-9-19(10-3-1)11-8-16-25-18-24-22-14-6-4-12-20(22)17-21-13-5-7-15-23(21)24/h1-7,9-10,12-15,24-25H,8,11,16-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 725 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description
Displacement of [3H]Pyrilamine from human cloned histamine H1 receptor |
Bioorg Med Chem Lett 20: 935-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.064
BindingDB Entry DOI: 10.7270/Q2F47P8J |
More data for this
Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50310099
(CHEMBL597528 | N-((9,10-Dihydroanthracen-9-yl)meth...)Show InChI InChI=1S/C25H27N/c1-2-10-20(11-3-1)12-8-9-17-26-19-25-23-15-6-4-13-21(23)18-22-14-5-7-16-24(22)25/h1-7,10-11,13-16,25-26H,8-9,12,17-19H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 964 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description
Displacement of [3H]Pyrilamine from human cloned histamine H1 receptor |
Bioorg Med Chem Lett 20: 935-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.064
BindingDB Entry DOI: 10.7270/Q2F47P8J |
More data for this
Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50310096
((7,12-dihydro-3-methoxytetraphen-12-yl)methanamine...)Show InChI InChI=1S/C20H19NO/c1-22-16-8-9-18-14(11-16)6-7-15-10-13-4-2-3-5-17(13)19(12-21)20(15)18/h2-9,11,19H,10,12,21H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description
Displacement of [3H]Pyrilamine from human cloned histamine H1 receptor |
Bioorg Med Chem Lett 20: 935-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.064
BindingDB Entry DOI: 10.7270/Q2F47P8J |
More data for this
Ligand-Target Pair | |
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