Affinity Data by PubMed id=20045646

PubMed code 20045646

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Translocator protein (Rattus norvegicus (rat))	BDBM22032 (1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Translocator protein (Rattus norvegicus (rat))	BDBM50310140 (CHEMBL605154 \| N,N-Diethyl-3-iodomethyl-4-phenylqu...) Show SMILES CCN(CC)C(=O)c1nc2ccccc2c(-c2ccccc2)c1CI Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50310139 (CHEMBL601203 \| N-Benzyl-3-iodomethyl-N-methyl-4-ph...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50310141 (4-Phenyl-3-iodomethylquinoline-2-N-methyl-N-sec-bu...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	173	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50310138 (3-Iodomethyl-N-methyl-N-phenethyl-4-phenylquinolin...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	411	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50310137 (3-Methyl-4-phenylquinoline-2-N-methyl-N-(3-iodoben...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	455	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50310132 (4-(4-Fluorophenyl)quinoline-2-N-methyl-N-(4-iodobe...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50310133 (4-(4-Fluorophenyl)quinoline-2-N-methyl-N-(3-iodobe...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50310136 (3-Methyl-4-phenylquinoline-2-N-methyl-N-(4-iodoben...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50310135 (4-Phenylquinoline-2-N-methyl-N-(3-iodobenzyl)carbo...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50310134 (4-Phenylquinoline-2-N-methyl-N-(4-iodobenzyl)carbo...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Glasgow Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat brain homogenates by liquid scintillation counting				Bioorg Med Chem Lett 20: 954-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.061 BindingDB Entry DOI: 10.7270/Q2JH3N50
University of Glasgow Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%