Affinity Data by PubMed id=20056549

PubMed code 20056549

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM22966 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of COX2 in mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50310340 (3-(4-bromophenyl)-5-nitrobenzo[1.3.2]dithiazolium-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of LOX5 in human PMBL by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50029593 (CHEMBL7162 \| N-(2-(cyclohexyloxy)-4-nitrophenyl)me...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of COX2 in mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50310339 (3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of LOX5 in human PMBL by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50310340 (3-(4-bromophenyl)-5-nitrobenzo[1.3.2]dithiazolium-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50310339 (3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of human recombinant COX2 expressed in insect Sf9 cells by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50310339 (3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50310339 (3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of COX2 in mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50310339 (3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of human recombinant COX1 in human platelets by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50310340 (3-(4-bromophenyl)-5-nitrobenzo[1.3.2]dithiazolium-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of COX2 in mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM22966 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50029593 (CHEMBL7162 \| N-(2-(cyclohexyloxy)-4-nitrophenyl)me...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%