Affinity Data by PubMed id=20061161

PubMed code 20061161

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50306357 (2-(4-(methylsulfonyl)phenyl)-3-phenylquinoline-4-c...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50306356 (4-amino-2-(4-(methylsulfonyl)phenyl)-3-phenylquino...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50306353 (2-(4-(methylsulfonyl)phenyl)-3-phenylquinoline \| C...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50306354 (4-methyl-2-(4-methylsulfonyl)phenyl)-3-phenylquino...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50306355 (3,4-diphenyl-2-(4-methylsulfonyl)phenyl)-quinoline...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50306355 (3,4-diphenyl-2-(4-methylsulfonyl)phenyl)-quinoline...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50306354 (4-methyl-2-(4-methylsulfonyl)phenyl)-3-phenylquino...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50306356 (4-amino-2-(4-(methylsulfonyl)phenyl)-3-phenylquino...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50306353 (2-(4-(methylsulfonyl)phenyl)-3-phenylquinoline \| C...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50306357 (2-(4-(methylsulfonyl)phenyl)-3-phenylquinoline-4-c...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shahid Beheshti University MC Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by enzyme chemiluminescent enzyme assay				Bioorg Med Chem 18: 1029-33 (2010) Article DOI: 10.1016/j.bmc.2009.12.060 BindingDB Entry DOI: 10.7270/Q2V40V94
Shahid Beheshti University MC Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%