Affinity Data by PubMed id=20067271

PubMed code 20067271

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415166 (CHEMBL578825) Show SMILES O=C1CC(Sc2ccccc12)C1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	0.0525	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415165 (CHEMBL570795) Show SMILES C(N1CCC(CC1)C1CCc2ccccc2S1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0575	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415164 (CHEMBL570529) Show SMILES O=C1CC(Oc2ccccc12)C1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0661	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415163 (CHEMBL571418) Show SMILES C(N1CCC2(CC1)OCc1ccccc1S2)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.0891	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415162 (CHEMBL572294) Show SMILES C(N1CCC2(CC1)OCc1ccccc1O2)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.0977	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415161 (CHEMBL570067) Show SMILES O=C1CC(Oc2ccccc12)C1CCN(CCc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415160 (CHEMBL571659) Show SMILES O=C1CC2(CCN(Cc3ccccc3)CC2)Oc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.209	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415159 (CHEMBL570789) Show SMILES C(N1CCC2(CC1)CCc1ccccc1C2)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.437	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064172 (1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...) Show SMILES C(N1CCC2(CC1)CCc1ccccc1S2)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064171 (1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...) Show SMILES C(N1CCC2(CC1)CCc1ccccc1O2)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.617	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	7.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%