Found 63 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307331
((2-Carbamimidoylbenzo[b]thiophen-6-yloxy)thiophen-...)Show SMILES COC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1cccs1 Show InChI InChI=1S/C22H18N2O3S2/c1-26-22(25)20(18-6-3-9-28-18)27-16-5-2-4-13(11-16)14-7-8-17-15(10-14)12-19(29-17)21(23)24/h2-12,20H,1H3,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307328
((2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-(4-chlo...)Show SMILES COC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H19ClN2O3S/c1-29-24(28)22(14-5-8-18(25)9-6-14)30-19-4-2-3-15(12-19)16-7-10-20-17(11-16)13-21(31-20)23(26)27/h2-13,22H,1H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307328
((2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-(4-chlo...)Show SMILES COC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H19ClN2O3S/c1-29-24(28)22(14-5-8-18(25)9-6-14)30-19-4-2-3-15(12-19)16-7-10-20-17(11-16)13-21(31-20)23(26)27/h2-13,22H,1H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307327
((2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-(4-fluo...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OC(C(O)=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C23H17FN2O3S/c24-17-7-4-13(5-8-17)21(23(27)28)29-18-3-1-2-14(11-18)15-6-9-19-16(10-15)12-20(30-19)22(25)26/h1-12,21H,(H3,25,26)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307331
((2-Carbamimidoylbenzo[b]thiophen-6-yloxy)thiophen-...)Show SMILES COC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1cccs1 Show InChI InChI=1S/C22H18N2O3S2/c1-26-22(25)20(18-6-3-9-28-18)27-16-5-2-4-13(11-16)14-7-8-17-15(10-14)12-19(29-17)21(23)24/h2-12,20H,1H3,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307329
(3-(2-Carbamimidoylbenzo[b]thiophen-6-yloxy)-3-(4-c...)Show SMILES COC(=O)CC(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H21ClN2O3S/c1-30-24(29)14-21(15-5-8-19(26)9-6-15)31-20-4-2-3-16(12-20)17-7-10-22-18(11-17)13-23(32-22)25(27)28/h2-13,21H,14H2,1H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307320
(6-(3-Chloro-4-fluorobenzyloxy)benzo[b]thiophene-2-...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(F)c(Cl)c2)c1 Show InChI InChI=1S/C22H16ClFN2OS/c23-18-8-13(4-6-19(18)24)12-27-17-3-1-2-14(10-17)15-5-7-20-16(9-15)11-21(28-20)22(25)26/h1-11H,12H2,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307329
(3-(2-Carbamimidoylbenzo[b]thiophen-6-yloxy)-3-(4-c...)Show SMILES COC(=O)CC(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H21ClN2O3S/c1-30-24(29)14-21(15-5-8-19(26)9-6-15)31-20-4-2-3-16(12-20)17-7-10-22-18(11-17)13-23(32-22)25(27)28/h2-13,21H,14H2,1H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307330
(4-(2-Carbamimidoylbenzo[b]thiophen-6-yloxy)-4-(4-c...)Show SMILES COC(=O)CCC(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H23ClN2O3S/c1-31-25(30)12-10-22(16-5-8-20(27)9-6-16)32-21-4-2-3-17(14-21)18-7-11-23-19(13-18)15-24(33-23)26(28)29/h2-9,11,13-15,22H,10,12H2,1H3,(H3,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307330
(4-(2-Carbamimidoylbenzo[b]thiophen-6-yloxy)-4-(4-c...)Show SMILES COC(=O)CCC(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H23ClN2O3S/c1-31-25(30)12-10-22(16-5-8-20(27)9-6-16)32-21-4-2-3-17(14-21)18-7-11-23-19(13-18)15-24(33-23)26(28)29/h2-9,11,13-15,22H,10,12H2,1H3,(H3,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307326
((2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-(4-fluo...)Show SMILES COC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(F)cc1 Show InChI InChI=1S/C24H19FN2O3S/c1-29-24(28)22(14-5-8-18(25)9-6-14)30-19-4-2-3-15(12-19)16-7-10-20-17(11-16)13-21(31-20)23(26)27/h2-13,22H,1H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307326
((2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-(4-fluo...)Show SMILES COC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(F)cc1 Show InChI InChI=1S/C24H19FN2O3S/c1-29-24(28)22(14-5-8-18(25)9-6-14)30-19-4-2-3-15(12-19)16-7-10-20-17(11-16)13-21(31-20)23(26)27/h2-13,22H,1H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307320
(6-(3-Chloro-4-fluorobenzyloxy)benzo[b]thiophene-2-...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(F)c(Cl)c2)c1 Show InChI InChI=1S/C22H16ClFN2OS/c23-18-8-13(4-6-19(18)24)12-27-17-3-1-2-14(10-17)15-5-7-20-16(9-15)11-21(28-20)22(25)26/h1-11H,12H2,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307319
(6-(4-Chloro-3-fluoro-benzyloxy)-benzo[b]thiophene-...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(Cl)c(F)c2)c1 Show InChI InChI=1S/C22H16ClFN2OS/c23-18-6-4-13(8-19(18)24)12-27-17-3-1-2-14(10-17)15-5-7-20-16(9-15)11-21(28-20)22(25)26/h1-11H,12H2,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307319
(6-(4-Chloro-3-fluoro-benzyloxy)-benzo[b]thiophene-...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(Cl)c(F)c2)c1 Show InChI InChI=1S/C22H16ClFN2OS/c23-18-6-4-13(8-19(18)24)12-27-17-3-1-2-14(10-17)15-5-7-20-16(9-15)11-21(28-20)22(25)26/h1-11H,12H2,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 105 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307343
(6-(4-Methoxy-benzyloxy)-benzo[b]thiophene-2-carbox...)Show SMILES COc1ccc(COc2cccc(c2)-c2ccc3sc(cc3c2)C(N)=N)cc1 Show InChI InChI=1S/C23H20N2O2S/c1-26-19-8-5-15(6-9-19)14-27-20-4-2-3-16(12-20)17-7-10-21-18(11-17)13-22(28-21)23(24)25/h2-13H,14H2,1H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | 
3D Structure (docked) |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307323
(6-(Thiophen-2-ylmethoxy)benzo[b]thiophene-2-carbox...)Show InChI InChI=1S/C14H12N2OS2/c15-14(16)13-6-9-3-4-10(7-12(9)19-13)17-8-11-2-1-5-18-11/h1-7H,8H2,(H3,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307342
(6-(3-Methoxy-benzyloxy)-benzo[b]thiophene-2-carbox...)Show SMILES COc1cccc(COc2cccc(c2)-c2ccc3sc(cc3c2)C(N)=N)c1 Show InChI InChI=1S/C23H20N2O2S/c1-26-19-6-2-4-15(10-19)14-27-20-7-3-5-16(12-20)17-8-9-21-18(11-17)13-22(28-21)23(24)25/h2-13H,14H2,1H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307318
(6-(3,4-Difluoro-benzyloxy)-benzo[b]thiophene-2-car...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(F)c(F)c2)c1 Show InChI InChI=1S/C22H16F2N2OS/c23-18-6-4-13(8-19(18)24)12-27-17-3-1-2-14(10-17)15-5-7-20-16(9-15)11-21(28-20)22(25)26/h1-11H,12H2,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307341
(6-(4-Chloro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C22H17ClN2OS/c23-18-7-4-14(5-8-18)13-26-19-3-1-2-15(11-19)16-6-9-20-17(10-16)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307337
((2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-acetic ...)Show InChI InChI=1S/C19H18N2O3S/c1-2-23-18(22)11-24-15-5-3-4-12(9-15)13-6-7-16-14(8-13)10-17(25-16)19(20)21/h3-10H,2,11H2,1H3,(H3,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307338
(6-(3-Fluoro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2cccc(F)c2)c1 Show InChI InChI=1S/C22H17FN2OS/c23-18-5-1-3-14(9-18)13-26-19-6-2-4-15(11-19)16-7-8-20-17(10-16)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307339
(6-(4-Fluoro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(F)cc2)c1 Show InChI InChI=1S/C22H17FN2OS/c23-18-7-4-14(5-8-18)13-26-19-3-1-2-15(11-19)16-6-9-20-17(10-16)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307333
(4-(Benzothiazol-2-ylmethoxy)-benzo[b]thiophene-2-c...)Show InChI InChI=1S/C17H13N3OS2/c18-17(19)15-8-10-12(5-3-7-13(10)22-15)21-9-16-20-11-4-1-2-6-14(11)23-16/h1-8H,9H2,(H3,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307340
(6-(3-Chloro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2cccc(Cl)c2)c1 Show InChI InChI=1S/C22H17ClN2OS/c23-18-5-1-3-14(9-18)13-26-19-6-2-4-15(11-19)16-7-8-20-17(10-16)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307344
(6-(4-Methyl-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES Cc1ccc(COc2cccc(c2)-c2ccc3sc(cc3c2)C(N)=N)cc1 Show InChI InChI=1S/C23H20N2OS/c1-15-5-7-16(8-6-15)14-26-20-4-2-3-17(12-20)18-9-10-21-19(11-18)13-22(27-21)23(24)25/h2-13H,14H2,1H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307327
((2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-(4-fluo...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OC(C(O)=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C23H17FN2O3S/c24-17-7-4-13(5-8-17)21(23(27)28)29-18-3-1-2-14(11-18)15-6-9-19-16(10-15)12-20(30-19)22(25)26/h1-12,21H,(H3,25,26)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50098137
(2-amidino-4-iodobenzothiophene | 4-Iodo-benzo[b]th...)Show InChI InChI=1S/C9H7IN2S/c10-6-2-1-3-7-5(6)4-8(13-7)9(11)12/h1-4H,(H3,11,12) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307322
(6-(Pyridin-3-ylmethoxy)-benzo[b]thiophene-2-carbox...)Show InChI InChI=1S/C15H13N3OS/c16-15(17)14-6-11-3-4-12(7-13(11)20-14)19-9-10-2-1-5-18-8-10/h1-8H,9H2,(H3,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307323
(6-(Thiophen-2-ylmethoxy)benzo[b]thiophene-2-carbox...)Show InChI InChI=1S/C14H12N2OS2/c15-14(16)13-6-9-3-4-10(7-12(9)19-13)17-8-11-2-1-5-18-11/h1-7H,8H2,(H3,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307332
(4-Benzyloxybenzo[b]thiophene-2-carboxamidine | CHE...)Show InChI InChI=1S/C16H14N2OS/c17-16(18)15-9-12-13(7-4-8-14(12)20-15)19-10-11-5-2-1-3-6-11/h1-9H,10H2,(H3,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307346
(4-Phenyl-benzo[b]thiophene-2-carboxamidine | CHEMB...)Show InChI InChI=1S/C15H12N2S/c16-15(17)14-9-12-11(7-4-8-13(12)18-14)10-5-2-1-3-6-10/h1-9H,(H3,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307335
(5-Benzyloxy-benzo[b]thiophene-2-carboxamidine | CH...)Show InChI InChI=1S/C22H18N2OS/c23-22(24)21-13-18-12-17(8-11-20(18)26-21)16-6-9-19(10-7-16)25-14-15-4-2-1-3-5-15/h1-13H,14H2,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307325
(2-(2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-2-(4-...)Show SMILES NC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(F)cc1 Show InChI InChI=1S/C23H18FN3O2S/c24-17-7-4-13(5-8-17)21(23(27)28)29-18-3-1-2-14(11-18)15-6-9-19-16(10-15)12-20(30-19)22(25)26/h1-12,21H,(H3,25,26)(H2,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307333
(4-(Benzothiazol-2-ylmethoxy)-benzo[b]thiophene-2-c...)Show InChI InChI=1S/C17H13N3OS2/c18-17(19)15-8-10-12(5-3-7-13(10)22-15)21-9-16-20-11-4-1-2-6-14(11)23-16/h1-8H,9H2,(H3,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307341
(6-(4-Chloro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C22H17ClN2OS/c23-18-7-4-14(5-8-18)13-26-19-3-1-2-15(11-19)16-6-9-20-17(10-16)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307322
(6-(Pyridin-3-ylmethoxy)-benzo[b]thiophene-2-carbox...)Show InChI InChI=1S/C15H13N3OS/c16-15(17)14-6-11-3-4-12(7-13(11)20-14)19-9-10-2-1-5-18-8-10/h1-8H,9H2,(H3,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307335
(5-Benzyloxy-benzo[b]thiophene-2-carboxamidine | CH...)Show InChI InChI=1S/C22H18N2OS/c23-22(24)21-13-18-12-17(8-11-20(18)26-21)16-6-9-19(10-7-16)25-14-15-4-2-1-3-5-15/h1-13H,14H2,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307336
(6-Benzyloxybenzo[b]thiophene-2-carboxamidine | CHE...)Show InChI InChI=1S/C22H18N2OS/c23-22(24)21-13-18-11-17(9-10-20(18)26-21)16-7-4-8-19(12-16)25-14-15-5-2-1-3-6-15/h1-13H,14H2,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307337
((2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-acetic ...)Show InChI InChI=1S/C19H18N2O3S/c1-2-23-18(22)11-24-15-5-3-4-12(9-15)13-6-7-16-14(8-13)10-17(25-16)19(20)21/h3-10H,2,11H2,1H3,(H3,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307342
(6-(3-Methoxy-benzyloxy)-benzo[b]thiophene-2-carbox...)Show SMILES COc1cccc(COc2cccc(c2)-c2ccc3sc(cc3c2)C(N)=N)c1 Show InChI InChI=1S/C23H20N2O2S/c1-26-19-6-2-4-15(10-19)14-27-20-7-3-5-16(12-20)17-8-9-21-18(11-17)13-22(28-21)23(24)25/h2-13H,14H2,1H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307340
(6-(3-Chloro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2cccc(Cl)c2)c1 Show InChI InChI=1S/C22H17ClN2OS/c23-18-5-1-3-14(9-18)13-26-19-6-2-4-15(11-19)16-7-8-20-17(10-16)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307318
(6-(3,4-Difluoro-benzyloxy)-benzo[b]thiophene-2-car...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(F)c(F)c2)c1 Show InChI InChI=1S/C22H16F2N2OS/c23-18-6-4-13(8-19(18)24)12-27-17-3-1-2-14(10-17)15-5-7-20-16(9-15)11-21(28-20)22(25)26/h1-11H,12H2,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307334
(5-(3,4-Dimethoxyphenyl)benzo[b]thiophene-2-carboxa...)Show InChI InChI=1S/C17H16N2O2S/c1-20-13-5-3-11(8-14(13)21-2)10-4-6-15-12(7-10)9-16(22-15)17(18)19/h3-9H,1-2H3,(H3,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| MMDB
Article
PubMed
| 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307332
(4-Benzyloxybenzo[b]thiophene-2-carboxamidine | CHE...)Show InChI InChI=1S/C16H14N2OS/c17-16(18)15-9-12-13(7-4-8-14(12)20-15)19-10-11-5-2-1-3-6-11/h1-9H,10H2,(H3,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307338
(6-(3-Fluoro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2cccc(F)c2)c1 Show InChI InChI=1S/C22H17FN2OS/c23-18-5-1-3-14(9-18)13-26-19-6-2-4-15(11-19)16-7-8-20-17(10-16)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307350
(6-(2-Chloro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccccc2Cl)c1 Show InChI InChI=1S/C22H17ClN2OS/c23-19-7-2-1-4-16(19)13-26-18-6-3-5-14(11-18)15-8-9-20-17(10-15)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307339
(6-(4-Fluoro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccc(F)cc2)c1 Show InChI InChI=1S/C22H17FN2OS/c23-18-7-4-14(5-8-18)13-26-19-3-1-2-15(11-19)16-6-9-20-17(10-16)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307344
(6-(4-Methyl-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES Cc1ccc(COc2cccc(c2)-c2ccc3sc(cc3c2)C(N)=N)cc1 Show InChI InChI=1S/C23H20N2OS/c1-15-5-7-16(8-6-15)14-26-20-4-2-3-17(12-20)18-9-10-21-19(11-18)13-22(27-21)23(24)25/h2-13H,14H2,1H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50378617
(CHEMBL1204017)Show InChI InChI=1S/C15H12N2S/c16-15(17)14-9-12-8-11(6-7-13(12)18-14)10-4-2-1-3-5-10/h1-9H,(H3,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307317
(4-(2-Carbamimidoyl-benzo[b]thiophen-6-yloxymethyl)...)Show SMILES CC(=O)Oc1ccc(COc2cccc(c2)-c2ccc3sc(cc3c2)C(N)=N)cc1 Show InChI InChI=1S/C24H20N2O3S/c1-15(27)29-20-8-5-16(6-9-20)14-28-21-4-2-3-17(12-21)18-7-10-22-19(11-18)13-23(30-22)24(25)26/h2-13H,14H2,1H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307324
(6-[1-(4-Fluoro-phenyl)-ethoxy]-benzo[b]thiophene-2...)Show SMILES CC(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(F)cc1 Show InChI InChI=1S/C23H19FN2OS/c1-14(15-5-8-19(24)9-6-15)27-20-4-2-3-16(12-20)17-7-10-21-18(11-17)13-22(28-21)23(25)26/h2-14H,1H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307345
((2-Carbamimidoyl-benzo[b]thiophen-4-yloxy)-acetic ...)Show InChI InChI=1S/C13H14N2O3S/c1-2-17-12(16)7-18-9-4-3-5-10-8(9)6-11(19-10)13(14)15/h3-6H,2,7H2,1H3,(H3,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307334
(5-(3,4-Dimethoxyphenyl)benzo[b]thiophene-2-carboxa...)Show InChI InChI=1S/C17H16N2O2S/c1-20-13-5-3-11(8-14(13)21-2)10-4-6-15-12(7-10)9-16(22-15)17(18)19/h3-9H,1-2H3,(H3,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307343
(6-(4-Methoxy-benzyloxy)-benzo[b]thiophene-2-carbox...)Show SMILES COc1ccc(COc2cccc(c2)-c2ccc3sc(cc3c2)C(N)=N)cc1 Show InChI InChI=1S/C23H20N2O2S/c1-26-19-8-5-15(6-9-19)14-27-20-4-2-3-16(12-20)17-7-10-21-18(11-17)13-22(28-21)23(24)25/h2-13H,14H2,1H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307336
(6-Benzyloxybenzo[b]thiophene-2-carboxamidine | CHE...)Show InChI InChI=1S/C22H18N2OS/c23-22(24)21-13-18-11-17(9-10-20(18)26-21)16-7-4-8-19(12-16)25-14-15-5-2-1-3-6-15/h1-13H,14H2,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307321
(6-Phenethyloxy-benzo[b]thiophene-2-carboxamidine |...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCCc2ccccc2)c1 Show InChI InChI=1S/C23H20N2OS/c24-23(25)22-15-19-13-18(9-10-21(19)27-22)17-7-4-8-20(14-17)26-12-11-16-5-2-1-3-6-16/h1-10,13-15H,11-12H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50098137
(2-amidino-4-iodobenzothiophene | 4-Iodo-benzo[b]th...)Show InChI InChI=1S/C9H7IN2S/c10-6-2-1-3-7-5(6)4-8(13-7)9(11)12/h1-4H,(H3,11,12) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307349
(6-(2-Fluoro-benzyloxy)-benzo[b]thiophene-2-carboxa...)Show SMILES NC(=N)c1cc2cc(ccc2s1)-c1cccc(OCc2ccccc2F)c1 Show InChI InChI=1S/C22H17FN2OS/c23-19-7-2-1-4-16(19)13-26-18-6-3-5-14(11-18)15-8-9-20-17(10-15)12-21(27-20)22(24)25/h1-12H,13H2,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307348
(6-(3,4-Dimethoxy-phenyl)-benzo[b]thiophene-2-carbo...)Show SMILES COc1ccc(cc1OC)-c1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N Show InChI InChI=1S/C23H20N2O2S/c1-26-19-8-6-17(12-20(19)27-2)15-5-3-4-14(10-15)16-7-9-21-18(11-16)13-22(28-21)23(24)25/h3-13H,1-2H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307351
(6-(2-Methoxy-benzyloxy)-benzo[b]thiophene-2-carbox...)Show SMILES COc1ccccc1COc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N Show InChI InChI=1S/C23H20N2O2S/c1-26-20-8-3-2-5-17(20)14-27-19-7-4-6-15(12-19)16-9-10-21-18(11-16)13-22(28-21)23(24)25/h2-13H,14H2,1H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307325
(2-(2-Carbamimidoyl-benzo[b]thiophen-6-yloxy)-2-(4-...)Show SMILES NC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1ccc(F)cc1 Show InChI InChI=1S/C23H18FN3O2S/c24-17-7-4-13(5-8-17)21(23(27)28)29-18-3-1-2-14(11-18)15-6-9-19-16(10-15)12-20(30-19)22(25)26/h1-12,21H,(H3,25,26)(H2,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of factor 10 by amidolytic assay |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50098137
(2-amidino-4-iodobenzothiophene | 4-Iodo-benzo[b]th...)Show InChI InChI=1S/C9H7IN2S/c10-6-2-1-3-7-5(6)4-8(13-7)9(11)12/h1-4H,(H3,11,12) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of uPA |
J Med Chem 53: 1465-72 (2010)
Article DOI: 10.1021/jm901475e
BindingDB Entry DOI: 10.7270/Q22N5372 |
More data for this
Ligand-Target Pair | |
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