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PubMed code 20143840

Compile data set for download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314133
PNG
(CHEMBL1093713 | N-(3,5-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1cc(C)cc(NC(=O)CCCCC(=O)NO)c1
Show InChI InChI=1S/C14H20N2O3/c1-10-7-11(2)9-12(8-10)15-13(17)5-3-4-6-14(18)16-19/h7-9,19H,3-6H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 17n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314134
PNG
(CHEMBL1093041 | N-(3-Ethylphenyl)-N'-hydroxyoctane...)
Show SMILES CCc1cccc(NC(=O)CCCCC(=O)NO)c1
Show InChI InChI=1S/C14H20N2O3/c1-2-11-6-5-7-12(10-11)15-13(17)8-3-4-9-14(18)16-19/h5-7,10,19H,2-4,8-9H2,1H3,(H,15,17)(H,16,18)
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n/an/a 27n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314135
PNG
(CHEMBL1093359 | N-(3,4-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1ccc(NC(=O)CCCCC(=O)NO)cc1C
Show InChI InChI=1S/C14H20N2O3/c1-10-7-8-12(9-11(10)2)15-13(17)5-3-4-6-14(18)16-19/h7-9,19H,3-6H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 30n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314133
PNG
(CHEMBL1093713 | N-(3,5-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1cc(C)cc(NC(=O)CCCCC(=O)NO)c1
Show InChI InChI=1S/C14H20N2O3/c1-10-7-11(2)9-12(8-10)15-13(17)5-3-4-6-14(18)16-19/h7-9,19H,3-6H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 30n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314134
PNG
(CHEMBL1093041 | N-(3-Ethylphenyl)-N'-hydroxyoctane...)
Show SMILES CCc1cccc(NC(=O)CCCCC(=O)NO)c1
Show InChI InChI=1S/C14H20N2O3/c1-2-11-6-5-7-12(10-11)15-13(17)8-3-4-9-14(18)16-19/h5-7,10,19H,2-4,8-9H2,1H3,(H,15,17)(H,16,18)
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n/an/a 35n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314135
PNG
(CHEMBL1093359 | N-(3,4-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1ccc(NC(=O)CCCCC(=O)NO)cc1C
Show InChI InChI=1S/C14H20N2O3/c1-10-7-8-12(9-11(10)2)15-13(17)5-3-4-6-14(18)16-19/h7-9,19H,3-6H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 56n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314136
PNG
(CHEMBL1089339 | N-Hydroxy-N'-(3-methylphenyl)octan...)
Show SMILES Cc1cccc(NC(=O)CCCCC(=O)NO)c1
Show InChI InChI=1S/C13H18N2O3/c1-10-5-4-6-11(9-10)14-12(16)7-2-3-8-13(17)15-18/h4-6,9,18H,2-3,7-8H2,1H3,(H,14,16)(H,15,17)
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n/an/a 57n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314136
PNG
(CHEMBL1089339 | N-Hydroxy-N'-(3-methylphenyl)octan...)
Show SMILES Cc1cccc(NC(=O)CCCCC(=O)NO)c1
Show InChI InChI=1S/C13H18N2O3/c1-10-5-4-6-11(9-10)14-12(16)7-2-3-8-13(17)15-18/h4-6,9,18H,2-3,7-8H2,1H3,(H,14,16)(H,15,17)
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n/an/a 58n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314137
PNG
(CHEMBL1091487 | N-Hydroxy-N'-(4-methoxyphenyl)octa...)
Show SMILES COc1ccc(NC(=O)CCCCC(=O)NO)cc1
Show InChI InChI=1S/C13H18N2O4/c1-19-11-8-6-10(7-9-11)14-12(16)4-2-3-5-13(17)15-18/h6-9,18H,2-5H2,1H3,(H,14,16)(H,15,17)
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n/an/a 71n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314138
PNG
(CHEMBL1092762 | N-Hydroxy-N'-(4-methylphenyl)octan...)
Show SMILES Cc1ccc(NC(=O)CCCCC(=O)NO)cc1
Show InChI InChI=1S/C13H18N2O3/c1-10-6-8-11(9-7-10)14-12(16)4-2-3-5-13(17)15-18/h6-9,18H,2-5H2,1H3,(H,14,16)(H,15,17)
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n/an/a 76n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314138
PNG
(CHEMBL1092762 | N-Hydroxy-N'-(4-methylphenyl)octan...)
Show SMILES Cc1ccc(NC(=O)CCCCC(=O)NO)cc1
Show InChI InChI=1S/C13H18N2O3/c1-10-6-8-11(9-7-10)14-12(16)4-2-3-5-13(17)15-18/h6-9,18H,2-5H2,1H3,(H,14,16)(H,15,17)
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n/an/a 114n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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n/an/a 119n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314137
PNG
(CHEMBL1091487 | N-Hydroxy-N'-(4-methoxyphenyl)octa...)
Show SMILES COc1ccc(NC(=O)CCCCC(=O)NO)cc1
Show InChI InChI=1S/C13H18N2O4/c1-19-11-8-6-10(7-9-11)14-12(16)4-2-3-5-13(17)15-18/h6-9,18H,2-5H2,1H3,(H,14,16)(H,15,17)
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n/an/a 137n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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n/an/a 147n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314139
PNG
(CHEMBL1093042 | N-(4-Ethylphenyl)-N'-hydroxyoctane...)
Show SMILES CCc1ccc(NC(=O)CCCCC(=O)NO)cc1
Show InChI InChI=1S/C14H20N2O3/c1-2-11-7-9-12(10-8-11)15-13(17)5-3-4-6-14(18)16-19/h7-10,19H,2-6H2,1H3,(H,15,17)(H,16,18)
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n/an/a 149n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314139
PNG
(CHEMBL1093042 | N-(4-Ethylphenyl)-N'-hydroxyoctane...)
Show SMILES CCc1ccc(NC(=O)CCCCC(=O)NO)cc1
Show InChI InChI=1S/C14H20N2O3/c1-2-11-7-9-12(10-8-11)15-13(17)5-3-4-6-14(18)16-19/h7-10,19H,2-6H2,1H3,(H,15,17)(H,16,18)
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n/an/a 240n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314140
PNG
(CHEMBL1076794 | N-Hydroxy-N'-(2-methylphenyl)octan...)
Show SMILES Cc1ccccc1NC(=O)CCCCC(=O)NO
Show InChI InChI=1S/C13H18N2O3/c1-10-6-2-3-7-11(10)14-12(16)8-4-5-9-13(17)15-18/h2-3,6-7,18H,4-5,8-9H2,1H3,(H,14,16)(H,15,17)
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n/an/a 576n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314141
PNG
(CHEMBL1092032 | N-(2,4-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1ccc(NC(=O)CCCCC(=O)NO)c(C)c1
Show InChI InChI=1S/C14H20N2O3/c1-10-7-8-12(11(2)9-10)15-13(17)5-3-4-6-14(18)16-19/h7-9,19H,3-6H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 638n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314141
PNG
(CHEMBL1092032 | N-(2,4-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1ccc(NC(=O)CCCCC(=O)NO)c(C)c1
Show InChI InChI=1S/C14H20N2O3/c1-10-7-8-12(11(2)9-10)15-13(17)5-3-4-6-14(18)16-19/h7-9,19H,3-6H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 1.10E+3n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314142
PNG
(CHEMBL1093040 | N-(2-Ethylphenyl)-N'-hydroxyoctane...)
Show SMILES CCc1ccccc1NC(=O)CCCCC(=O)NO
Show InChI InChI=1S/C14H20N2O3/c1-2-11-7-3-4-8-12(11)15-13(17)9-5-6-10-14(18)16-19/h3-4,7-8,19H,2,5-6,9-10H2,1H3,(H,15,17)(H,16,18)
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n/an/a 1.10E+3n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314143
PNG
(CHEMBL1093043 | N-(2,3-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1cccc(NC(=O)CCCCC(=O)NO)c1C
Show InChI InChI=1S/C14H20N2O3/c1-10-6-5-7-12(11(10)2)15-13(17)8-3-4-9-14(18)16-19/h5-7,19H,3-4,8-9H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 1.11E+3n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314144
PNG
(CHEMBL1093357 | N-(2,5-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1ccc(C)c(NC(=O)CCCCC(=O)NO)c1
Show InChI InChI=1S/C14H20N2O3/c1-10-7-8-11(2)12(9-10)15-13(17)5-3-4-6-14(18)16-19/h7-9,19H,3-6H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 1.14E+3n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314144
PNG
(CHEMBL1093357 | N-(2,5-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1ccc(C)c(NC(=O)CCCCC(=O)NO)c1
Show InChI InChI=1S/C14H20N2O3/c1-10-7-8-11(2)12(9-10)15-13(17)5-3-4-6-14(18)16-19/h7-9,19H,3-6H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 1.35E+3n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314140
PNG
(CHEMBL1076794 | N-Hydroxy-N'-(2-methylphenyl)octan...)
Show SMILES Cc1ccccc1NC(=O)CCCCC(=O)NO
Show InChI InChI=1S/C13H18N2O3/c1-10-6-2-3-7-11(10)14-12(16)8-4-5-9-13(17)15-18/h2-3,6-7,18H,4-5,8-9H2,1H3,(H,14,16)(H,15,17)
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n/an/a 1.35E+3n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314143
PNG
(CHEMBL1093043 | N-(2,3-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1cccc(NC(=O)CCCCC(=O)NO)c1C
Show InChI InChI=1S/C14H20N2O3/c1-10-6-5-7-12(11(10)2)15-13(17)8-3-4-9-14(18)16-19/h5-7,19H,3-4,8-9H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 1.75E+3n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314142
PNG
(CHEMBL1093040 | N-(2-Ethylphenyl)-N'-hydroxyoctane...)
Show SMILES CCc1ccccc1NC(=O)CCCCC(=O)NO
Show InChI InChI=1S/C14H20N2O3/c1-2-11-7-3-4-8-12(11)15-13(17)9-5-6-10-14(18)16-19/h3-4,7-8,19H,2,5-6,9-10H2,1H3,(H,15,17)(H,16,18)
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n/an/a 2.26E+3n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))		BDBM50314145
PNG
(CHEMBL1093358 | N-(2,6-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1cccc(C)c1NC(=O)CCCCC(=O)NO
Show InChI InChI=1S/C14H20N2O3/c1-10-6-5-7-11(2)14(10)15-12(17)8-3-4-9-13(18)16-19/h5-7,19H,3-4,8-9H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 4.99E+3n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50314145
PNG
(CHEMBL1093358 | N-(2,6-Dimethylphenyl)-N'-hydroxyo...)
Show SMILES Cc1cccc(C)c1NC(=O)CCCCC(=O)NO
Show InChI InChI=1S/C14H20N2O3/c1-10-6-5-7-11(2)14(10)15-12(17)8-3-4-9-13(18)16-19/h5-7,19H,3-4,8-9H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 1.16E+4n/an/an/an/an/an/a



UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assay

J Med Chem 53: 1937-50 (2010)


Article DOI: 10.1021/jm901561u
BindingDB Entry DOI: 10.7270/Q2QJ7HFB
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%