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PubMed code 2016719

Compile data set for download or QSAR
Found 68 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM21173
PNG
(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1
Show InChI InChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18)
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 0.230n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50007838
PNG
(8-Cyclohexyl-1,3-dipropyl-3,7-dihydro-purine-2,6-d...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCCC1
Show InChI InChI=1S/C17H26N4O2/c1-3-10-20-15-13(16(22)21(11-4-2)17(20)23)18-14(19-15)12-8-6-5-7-9-12/h12H,3-11H2,1-2H3,(H,18,19)
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 0.300n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM82010
PNG
(1,3-Dipropyl-8-(4-hydroxyphenyl)xanthine | 8-(4-Hy...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C17H20N4O3/c1-3-9-20-15-13(16(23)21(10-4-2)17(20)24)18-14(19-15)11-5-7-12(22)8-6-11/h5-8,22H,3-4,9-10H2,1-2H3,(H,18,19)
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 0.630n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011824
PNG
(8-Cyclopentyl-1-methyl-3-propyl-3,7-dihydro-purine...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)C1CCCC1
Show InChI InChI=1S/C14H20N4O2/c1-3-8-18-12-10(13(19)17(2)14(18)20)15-11(16-12)9-6-4-5-7-9/h9H,3-8H2,1-2H3,(H,15,16)
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 0.850n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011842
PNG
(8-Cyclopentyl-3-methyl-1-propyl-3,7-dihydro-purine...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)C1CCCC1
Show InChI InChI=1S/C14H20N4O2/c1-3-8-18-13(19)10-12(17(2)14(18)20)16-11(15-10)9-6-4-5-7-9/h9H,3-8H2,1-2H3,(H,15,16)
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 1.10n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011838
PNG
(8-(4-Hydroxy-phenyl)-3-methyl-1-propyl-3,7-dihydro...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C15H16N4O3/c1-3-8-19-14(21)11-13(18(2)15(19)22)17-12(16-11)9-4-6-10(20)7-5-9/h4-7,20H,3,8H2,1-2H3,(H,16,17)
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 1.30n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011835
PNG
(8-Cyclohexyl-1-methyl-3-propyl-3,7-dihydro-purine-...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)C1CCCCC1
Show InChI InChI=1S/C15H22N4O2/c1-3-9-19-13-11(14(20)18(2)15(19)21)16-12(17-13)10-7-5-4-6-8-10/h10H,3-9H2,1-2H3,(H,16,17)
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 1.80n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011825
PNG
(1,3-Dipropyl-8-thiophen-3-yl-3,7-dihydro-purine-2,...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccsc1
Show InChI InChI=1S/C15H18N4O2S/c1-3-6-18-13-11(14(20)19(7-4-2)15(18)21)16-12(17-13)10-5-8-22-9-10/h5,8-9H,3-4,6-7H2,1-2H3,(H,16,17)
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 2n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011836
PNG
(8-(4-Hydroxy-phenyl)-1-methyl-3-propyl-3,7-dihydro...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C15H16N4O3/c1-3-8-19-13-11(14(21)18(2)15(19)22)16-12(17-13)9-4-6-10(20)7-5-9/h4-7,20H,3,8H2,1-2H3,(H,16,17)
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 2.5n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM82025
PNG
(1,3-Dipropyl-8-phenylxanthine | 8-Phenyl-1,3-dipro...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccccc1
Show InChI InChI=1S/C17H20N4O2/c1-3-10-20-15-13(16(22)21(11-4-2)17(20)23)18-14(19-15)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3,(H,18,19)
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 2.80n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011841
PNG
(1,3-Dipropyl-8-pyridin-4-yl-3,7-dihydro-purine-2,6...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccncc1
Show InChI InChI=1S/C16H19N5O2/c1-3-9-20-14-12(15(22)21(10-4-2)16(20)23)18-13(19-14)11-5-7-17-8-6-11/h5-8H,3-4,9-10H2,1-2H3,(H,18,19)
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 3.20n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50005366
PNG
(1,3-Dipropyl-8-thiophen-2-yl-3,7-dihydro-purine-2,...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cccs1
Show InChI InChI=1S/C15H18N4O2S/c1-3-7-18-13-11(14(20)19(8-4-2)15(18)21)16-12(17-13)10-6-5-9-22-10/h5-6,9H,3-4,7-8H2,1-2H3,(H,16,17)
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 3.20n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A1 receptor in rat cortex by displacement of [3H]-cyclohexyladenosine (CHA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011833
PNG
(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(cc1)C#N
Show InChI InChI=1S/C18H19N5O2/c1-3-9-22-16-14(17(24)23(10-4-2)18(22)25)20-15(21-16)13-7-5-12(11-19)6-8-13/h5-8H,3-4,9-10H2,1-2H3,(H,20,21)
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 4.5n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011846
PNG
(1-Methyl-3-propyl-8-thiophen-3-yl-3,7-dihydro-puri...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccsc1
Show InChI InChI=1S/C13H14N4O2S/c1-3-5-17-11-9(12(18)16(2)13(17)19)14-10(15-11)8-4-6-20-7-8/h4,6-7H,3,5H2,1-2H3,(H,14,15)
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 4.70n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A1 receptor in rat cortex by displacement of [3H]-cyclohexyladenosine (CHA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011839
PNG
(8-Cyclohexyl-3-methyl-1-propyl-3,7-dihydro-purine-...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)C1CCCCC1
Show InChI InChI=1S/C15H22N4O2/c1-3-9-19-14(20)11-13(18(2)15(19)21)17-12(16-11)10-7-5-4-6-8-10/h10H,3-9H2,1-2H3,(H,16,17)
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 5n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011845
PNG
(4-(3-Methyl-2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H15N5O2/c1-3-8-21-15(22)12-14(20(2)16(21)23)19-13(18-12)11-6-4-10(9-17)5-7-11/h4-7H,3,8H2,1-2H3,(H,18,19)
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 6n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011840
PNG
(1-Methyl-8-phenyl-3-propyl-3,7-dihydro-purine-2,6-...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccccc1
Show InChI InChI=1S/C15H16N4O2/c1-3-9-19-13-11(14(20)18(2)15(19)21)16-12(17-13)10-7-5-4-6-8-10/h4-8H,3,9H2,1-2H3,(H,16,17)
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 6.30n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011843
PNG
(3-Methyl-1-propyl-8-thiophen-3-yl-3,7-dihydro-puri...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccsc1
Show InChI InChI=1S/C13H14N4O2S/c1-3-5-17-12(18)9-11(16(2)13(17)19)15-10(14-9)8-4-6-20-7-8/h4,6-7H,3,5H2,1-2H3,(H,14,15)
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 6.40n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A1 receptor in rat cortex by displacement of [3H]-cyclohexyladenosine (CHA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011834
PNG
(3-Methyl-8-phenyl-1-propyl-3,7-dihydro-purine-2,6-...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccccc1
Show InChI InChI=1S/C15H16N4O2/c1-3-9-19-14(20)11-13(18(2)15(19)21)17-12(16-11)10-7-5-4-6-8-10/h4-8H,3,9H2,1-2H3,(H,16,17)
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 7n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011828
PNG
(1-Methyl-3-propyl-8-thiophen-2-yl-3,7-dihydro-puri...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1cccs1
Show InChI InChI=1S/C13H14N4O2S/c1-3-6-17-11-9(12(18)16(2)13(17)19)14-10(15-11)8-5-4-7-20-8/h4-5,7H,3,6H2,1-2H3,(H,14,15)
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 8.90n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011848
PNG
(3-Methyl-1-propyl-8-thiophen-2-yl-3,7-dihydro-puri...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1cccs1
Show InChI InChI=1S/C13H14N4O2S/c1-3-6-17-12(18)9-11(16(2)13(17)19)15-10(14-9)8-5-4-7-20-8/h4-5,7H,3,6H2,1-2H3,(H,14,15)
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 9.70n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A1 receptor in rat cortex by displacement of [3H]-cyclohexyladenosine (CHA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011849
PNG
(1,3-Dipropyl-8-pyridin-3-yl-3,7-dihydro-purine-2,6...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cccnc1
Show InChI InChI=1S/C16H19N5O2/c1-3-8-20-14-12(15(22)21(9-4-2)16(20)23)18-13(19-14)11-6-5-7-17-10-11/h5-7,10H,3-4,8-9H2,1-2H3,(H,18,19)
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 12n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A1 receptor in rat cortex by displacement of [3H]-cyclohexyladenosine (CHA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011844
PNG
(4-(1-Methyl-2,6-dioxo-3-propyl-2,3,6,7-tetrahydro-...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H15N5O2/c1-3-8-21-14-12(15(22)20(2)16(21)23)18-13(19-14)11-6-4-10(9-17)5-7-11/h4-7H,3,8H2,1-2H3,(H,18,19)
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 14n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50006713
PNG
(1,3-Dipropyl-8-styryl-3,7-dihydro-purine-2,6-dione...)
Show SMILES CCCn1c2nc(C=Cc3ccccc3)[nH]c2c(=O)n(CCC)c1=O |w:8.8|
Show InChI InChI=1S/C19H22N4O2/c1-3-12-22-17-16(18(24)23(13-4-2)19(22)25)20-15(21-17)11-10-14-8-6-5-7-9-14/h5-11H,3-4,12-13H2,1-2H3,(H,20,21)
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 22n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011829
PNG
(1-Methyl-3-propyl-8-pyridin-4-yl-3,7-dihydro-purin...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccncc1
Show InChI InChI=1S/C14H15N5O2/c1-3-8-19-12-10(13(20)18(2)14(19)21)16-11(17-12)9-4-6-15-7-5-9/h4-7H,3,8H2,1-2H3,(H,16,17)
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 22n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011847
PNG
(3-Methyl-1-propyl-8-pyridin-4-yl-3,7-dihydro-purin...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccncc1
Show InChI InChI=1S/C14H15N5O2/c1-3-8-19-13(20)10-12(18(2)14(19)21)17-11(16-10)9-4-6-15-7-5-9/h4-7H,3,8H2,1-2H3,(H,16,17)
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 28n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011830
PNG
(1-Methyl-3-propyl-8-styryl-3,7-dihydro-purine-2,6-...)
Show SMILES CCCn1c2nc(C=Cc3ccccc3)[nH]c2c(=O)n(C)c1=O |w:8.8|
Show InChI InChI=1S/C17H18N4O2/c1-3-11-21-15-14(16(22)20(2)17(21)23)18-13(19-15)10-9-12-7-5-4-6-8-12/h4-10H,3,11H2,1-2H3,(H,18,19)
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 31n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011825
PNG
(1,3-Dipropyl-8-thiophen-3-yl-3,7-dihydro-purine-2,...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccsc1
Show InChI InChI=1S/C15H18N4O2S/c1-3-6-18-13-11(14(20)19(7-4-2)15(18)21)16-12(17-13)10-5-8-22-9-10/h5,8-9H,3-4,6-7H2,1-2H3,(H,16,17)
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 39n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011830
PNG
(1-Methyl-3-propyl-8-styryl-3,7-dihydro-purine-2,6-...)
Show SMILES CCCn1c2nc(C=Cc3ccccc3)[nH]c2c(=O)n(C)c1=O |w:8.8|
Show InChI InChI=1S/C17H18N4O2/c1-3-11-21-15-14(16(22)20(2)17(21)23)18-13(19-15)10-9-12-7-5-4-6-8-12/h4-10H,3,11H2,1-2H3,(H,18,19)
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 47n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011823
PNG
(3-Methyl-1-propyl-8-styryl-3,7-dihydro-purine-2,6-...)
Show SMILES CCCn1c(=O)n(C)c2nc(C=Cc3ccccc3)[nH]c2c1=O |w:12.12|
Show InChI InChI=1S/C17H18N4O2/c1-3-11-21-16(22)14-15(20(2)17(21)23)19-13(18-14)10-9-12-7-5-4-6-8-12/h4-10H,3,11H2,1-2H3,(H,18,19)
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 50n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50006697
PNG
(8-Phenethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...)
Show SMILES CCCn1c2nc(CCc3ccccc3)[nH]c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C19H24N4O2/c1-3-12-22-17-16(18(24)23(13-4-2)19(22)25)20-15(21-17)11-10-14-8-6-5-7-9-14/h5-9H,3-4,10-13H2,1-2H3,(H,20,21)
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 58n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011823
PNG
(3-Methyl-1-propyl-8-styryl-3,7-dihydro-purine-2,6-...)
Show SMILES CCCn1c(=O)n(C)c2nc(C=Cc3ccccc3)[nH]c2c1=O |w:12.12|
Show InChI InChI=1S/C17H18N4O2/c1-3-11-21-16(22)14-15(20(2)17(21)23)19-13(18-14)10-9-12-7-5-4-6-8-12/h4-10H,3,11H2,1-2H3,(H,18,19)
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 58n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM82015
PNG
(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)
Show SMILES Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccccc1
Show InChI InChI=1S/C13H12N4O2/c1-16-11-9(12(18)17(2)13(16)19)14-10(15-11)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,14,15)
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 60n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM82010
PNG
(1,3-Dipropyl-8-(4-hydroxyphenyl)xanthine | 8-(4-Hy...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C17H20N4O3/c1-3-9-20-15-13(16(23)21(10-4-2)17(20)24)18-14(19-15)11-5-7-12(22)8-6-11/h5-8,22H,3-4,9-10H2,1-2H3,(H,18,19)
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 61n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011846
PNG
(1-Methyl-3-propyl-8-thiophen-3-yl-3,7-dihydro-puri...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccsc1
Show InChI InChI=1S/C13H14N4O2S/c1-3-5-17-11-9(12(18)16(2)13(17)19)14-10(15-11)8-4-6-20-7-8/h4,6-7H,3,5H2,1-2H3,(H,14,15)
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 70n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A2 receptor in rat striatum by displacement of [3H]N-ethyladenosine-5''-uronamide(NECA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011850
PNG
(3-Methyl-1-propyl-8-pyridin-3-yl-3,7-dihydro-purin...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1cccnc1
Show InChI InChI=1S/C14H15N5O2/c1-3-7-19-13(20)10-12(18(2)14(19)21)17-11(16-10)9-5-4-6-15-8-9/h4-6,8H,3,7H2,1-2H3,(H,16,17)
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 70n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A1 receptor in rat cortex by displacement of [3H]-cyclohexyladenosine (CHA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011837
PNG
(1-Methyl-3-propyl-8-pyridin-3-yl-3,7-dihydro-purin...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1cccnc1
Show InChI InChI=1S/C14H15N5O2/c1-3-7-19-12-10(13(20)18(2)14(19)21)16-11(17-12)9-5-4-6-15-8-9/h4-6,8H,3,7H2,1-2H3,(H,16,17)
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 73n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A1 receptor in rat cortex by displacement of [3H]-cyclohexyladenosine (CHA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011836
PNG
(8-(4-Hydroxy-phenyl)-1-methyl-3-propyl-3,7-dihydro...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C15H16N4O3/c1-3-8-19-13-11(14(21)18(2)15(19)22)16-12(17-13)9-4-6-10(20)7-5-9/h4-7,20H,3,8H2,1-2H3,(H,16,17)
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 82n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50006713
PNG
(1,3-Dipropyl-8-styryl-3,7-dihydro-purine-2,6-dione...)
Show SMILES CCCn1c2nc(C=Cc3ccccc3)[nH]c2c(=O)n(CCC)c1=O |w:8.8|
Show InChI InChI=1S/C19H22N4O2/c1-3-12-22-17-16(18(24)23(13-4-2)19(22)25)20-15(21-17)11-10-14-8-6-5-7-9-14/h5-11H,3-4,12-13H2,1-2H3,(H,20,21)
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 85n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011840
PNG
(1-Methyl-8-phenyl-3-propyl-3,7-dihydro-purine-2,6-...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccccc1
Show InChI InChI=1S/C15H16N4O2/c1-3-9-19-13-11(14(20)18(2)15(19)21)16-12(17-13)10-7-5-4-6-8-10/h4-8H,3,9H2,1-2H3,(H,16,17)
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 93n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM82025
PNG
(1,3-Dipropyl-8-phenylxanthine | 8-Phenyl-1,3-dipro...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccccc1
Show InChI InChI=1S/C17H20N4O2/c1-3-10-20-15-13(16(22)21(11-4-2)17(20)23)18-14(19-15)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3,(H,18,19)
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 116n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011841
PNG
(1,3-Dipropyl-8-pyridin-4-yl-3,7-dihydro-purine-2,6...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccncc1
Show InChI InChI=1S/C16H19N5O2/c1-3-9-20-14-12(15(22)21(10-4-2)16(20)23)18-13(19-14)11-5-7-17-8-6-11/h5-8H,3-4,9-10H2,1-2H3,(H,18,19)
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 136n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50005366
PNG
(1,3-Dipropyl-8-thiophen-2-yl-3,7-dihydro-purine-2,...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cccs1
Show InChI InChI=1S/C15H18N4O2S/c1-3-7-18-13-11(14(20)19(8-4-2)15(18)21)16-12(17-13)10-6-5-9-22-10/h5-6,9H,3-4,7-8H2,1-2H3,(H,16,17)
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 173n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A2 receptor in rat striatum by displacement of [3H]N-ethyladenosine-5''-uronamide(NECA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011833
PNG
(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(cc1)C#N
Show InChI InChI=1S/C18H19N5O2/c1-3-9-22-16-14(17(24)23(10-4-2)18(22)25)20-15(21-16)13-7-5-12(11-19)6-8-13/h5-8H,3-4,9-10H2,1-2H3,(H,20,21)
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 189n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM21173
PNG
(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1
Show InChI InChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18)
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 230n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011824
PNG
(8-Cyclopentyl-1-methyl-3-propyl-3,7-dihydro-purine...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)C1CCCC1
Show InChI InChI=1S/C14H20N4O2/c1-3-8-18-12-10(13(19)17(2)14(18)20)15-11(16-12)9-6-4-5-7-9/h9H,3-8H2,1-2H3,(H,15,16)
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 247n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011844
PNG
(4-(1-Methyl-2,6-dioxo-3-propyl-2,3,6,7-tetrahydro-...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H15N5O2/c1-3-8-21-14-12(15(22)20(2)16(21)23)18-13(19-14)11-6-4-10(9-17)5-7-11/h4-7H,3,8H2,1-2H3,(H,18,19)
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 254n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011827
PNG
(1-Methyl-8-phenethyl-3-propyl-3,7-dihydro-purine-2...)
Show SMILES CCCn1c2nc(CCc3ccccc3)[nH]c2c(=O)n(C)c1=O
Show InChI InChI=1S/C17H20N4O2/c1-3-11-21-15-14(16(22)20(2)17(21)23)18-13(19-15)10-9-12-7-5-4-6-8-12/h4-8H,3,9-11H2,1-2H3,(H,18,19)
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 259n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011838
PNG
(8-(4-Hydroxy-phenyl)-3-methyl-1-propyl-3,7-dihydro...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C15H16N4O3/c1-3-8-19-14(21)11-13(18(2)15(19)22)17-12(16-11)9-4-6-10(20)7-5-9/h4-7,20H,3,8H2,1-2H3,(H,16,17)
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 263n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50011831
PNG
(3-Methyl-8-phenethyl-1-propyl-3,7-dihydro-purine-2...)
Show SMILES CCCn1c(=O)n(C)c2nc(CCc3ccccc3)[nH]c2c1=O
Show InChI InChI=1S/C17H20N4O2/c1-3-11-21-16(22)14-15(20(2)17(21)23)19-13(18-14)10-9-12-7-5-4-6-8-12/h4-8H,3,9-11H2,1-2H3,(H,18,19)
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 275n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011843
PNG
(3-Methyl-1-propyl-8-thiophen-3-yl-3,7-dihydro-puri...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccsc1
Show InChI InChI=1S/C13H14N4O2S/c1-3-5-17-12(18)9-11(16(2)13(17)19)15-10(14-9)8-4-6-20-7-8/h4,6-7H,3,5H2,1-2H3,(H,14,15)
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 315n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A2 receptor in rat striatum by displacement of [3H]N-ethyladenosine-5''-uronamide(NECA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50007838
PNG
(8-Cyclohexyl-1,3-dipropyl-3,7-dihydro-purine-2,6-d...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCCC1
Show InChI InChI=1S/C17H26N4O2/c1-3-10-20-15-13(16(22)21(11-4-2)17(20)23)18-14(19-15)12-8-6-5-7-9-12/h12H,3-11H2,1-2H3,(H,18,19)
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 320n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011828
PNG
(1-Methyl-3-propyl-8-thiophen-2-yl-3,7-dihydro-puri...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1cccs1
Show InChI InChI=1S/C13H14N4O2S/c1-3-6-17-11-9(12(18)16(2)13(17)19)14-10(15-11)8-5-4-7-20-8/h4-5,7H,3,6H2,1-2H3,(H,14,15)
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 329n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011849
PNG
(1,3-Dipropyl-8-pyridin-3-yl-3,7-dihydro-purine-2,6...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cccnc1
Show InChI InChI=1S/C16H19N5O2/c1-3-8-20-14-12(15(22)21(9-4-2)16(20)23)18-13(19-14)11-6-5-7-17-10-11/h5-7,10H,3-4,8-9H2,1-2H3,(H,18,19)
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 347n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A2 receptor in rat striatum by displacement of [3H]N-ethyladenosine-5''-uronamide(NECA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011835
PNG
(8-Cyclohexyl-1-methyl-3-propyl-3,7-dihydro-purine-...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)C1CCCCC1
Show InChI InChI=1S/C15H22N4O2/c1-3-9-19-13-11(14(20)18(2)15(19)21)16-12(17-13)10-7-5-4-6-8-10/h10H,3-9H2,1-2H3,(H,16,17)
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 403n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011845
PNG
(4-(3-Methyl-2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H15N5O2/c1-3-8-21-15(22)12-14(20(2)16(21)23)19-13(18-12)11-6-4-10(9-17)5-7-11/h4-7H,3,8H2,1-2H3,(H,18,19)
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 446n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011829
PNG
(1-Methyl-3-propyl-8-pyridin-4-yl-3,7-dihydro-purin...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccncc1
Show InChI InChI=1S/C14H15N5O2/c1-3-8-19-12-10(13(20)18(2)14(19)21)16-11(17-12)9-4-6-15-7-5-9/h4-7H,3,8H2,1-2H3,(H,16,17)
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 476n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011834
PNG
(3-Methyl-8-phenyl-1-propyl-3,7-dihydro-purine-2,6-...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccccc1
Show InChI InChI=1S/C15H16N4O2/c1-3-9-19-14(20)11-13(18(2)15(19)21)17-12(16-11)10-7-5-4-6-8-10/h4-8H,3,9H2,1-2H3,(H,16,17)
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 553n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50006697
PNG
(8-Phenethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...)
Show SMILES CCCn1c2nc(CCc3ccccc3)[nH]c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C19H24N4O2/c1-3-12-22-17-16(18(24)23(13-4-2)19(22)25)20-15(21-17)11-10-14-8-6-5-7-9-14/h5-9H,3-4,10-13H2,1-2H3,(H,20,21)
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 593n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM82015
PNG
(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)
Show SMILES Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccccc1
Show InChI InChI=1S/C13H12N4O2/c1-16-11-9(12(18)17(2)13(16)19)14-10(15-11)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,14,15)
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 644n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011848
PNG
(3-Methyl-1-propyl-8-thiophen-2-yl-3,7-dihydro-puri...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1cccs1
Show InChI InChI=1S/C13H14N4O2S/c1-3-6-17-12(18)9-11(16(2)13(17)19)15-10(14-9)8-5-4-7-20-8/h4-5,7H,3,6H2,1-2H3,(H,14,15)
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 719n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A2 receptor in rat striatum by displacement of [3H]N-ethyladenosine-5''-uronamide(NECA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011839
PNG
(8-Cyclohexyl-3-methyl-1-propyl-3,7-dihydro-purine-...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)C1CCCCC1
Show InChI InChI=1S/C15H22N4O2/c1-3-9-19-14(20)11-13(18(2)15(19)21)17-12(16-11)10-7-5-4-6-8-10/h10H,3-9H2,1-2H3,(H,16,17)
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 995n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011842
PNG
(8-Cyclopentyl-3-methyl-1-propyl-3,7-dihydro-purine...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)C1CCCC1
Show InChI InChI=1S/C14H20N4O2/c1-3-8-18-13(19)10-12(17(2)14(18)20)16-11(15-10)9-6-4-5-7-9/h9H,3-8H2,1-2H3,(H,15,16)
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 1.01E+3n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011827
PNG
(1-Methyl-8-phenethyl-3-propyl-3,7-dihydro-purine-2...)
Show SMILES CCCn1c2nc(CCc3ccccc3)[nH]c2c(=O)n(C)c1=O
Show InChI InChI=1S/C17H20N4O2/c1-3-11-21-15-14(16(22)20(2)17(21)23)18-13(19-15)10-9-12-7-5-4-6-8-12/h4-8H,3,9-11H2,1-2H3,(H,18,19)
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 1.05E+3n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011837
PNG
(1-Methyl-3-propyl-8-pyridin-3-yl-3,7-dihydro-purin...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1cccnc1
Show InChI InChI=1S/C14H15N5O2/c1-3-7-19-12-10(13(20)18(2)14(19)21)16-11(17-12)9-5-4-6-15-8-9/h4-6,8H,3,7H2,1-2H3,(H,16,17)
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 1.20E+3n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A2 receptor in rat striatum by displacement of [3H]N-ethyladenosine-5''-uronamide(NECA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011831
PNG
(3-Methyl-8-phenethyl-1-propyl-3,7-dihydro-purine-2...)
Show SMILES CCCn1c(=O)n(C)c2nc(CCc3ccccc3)[nH]c2c1=O
Show InChI InChI=1S/C17H20N4O2/c1-3-11-21-16(22)14-15(20(2)17(21)23)19-13(18-14)10-9-12-7-5-4-6-8-12/h4-8H,3,9-11H2,1-2H3,(H,18,19)
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 1.44E+3n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011850
PNG
(3-Methyl-1-propyl-8-pyridin-3-yl-3,7-dihydro-purin...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1cccnc1
Show InChI InChI=1S/C14H15N5O2/c1-3-7-19-13(20)10-12(18(2)14(19)21)17-11(16-10)9-5-4-6-15-8-9/h4-6,8H,3,7H2,1-2H3,(H,16,17)
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 3.10E+3n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against Adenosine A2 receptor in rat striatum by displacement of [3H]N-ethyladenosine-5''-uronamide(NECA)

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
Adenosine receptor A2a/A2b


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50011847
PNG
(3-Methyl-1-propyl-8-pyridin-4-yl-3,7-dihydro-purin...)
Show SMILES CCCn1c(=O)n(C)c2nc([nH]c2c1=O)-c1ccncc1
Show InChI InChI=1S/C14H15N5O2/c1-3-8-19-13(20)10-12(18(2)14(19)21)17-11(16-10)9-4-6-15-7-5-9/h4-7H,3,8H2,1-2H3,(H,16,17)
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 3.76E+3n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).

J Med Chem 34: 1431-5 (1991)


BindingDB Entry DOI: 10.7270/Q2G73CP1
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%