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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50308552 ((1'S,2'R,3'S,4'R,5'S)-4-(6-Amino-2-chloro-9H-purin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 722 | n/a | n/a | n/a | n/a |
National Institutes of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Activation of human P2Y1 receptor expressed in human 1321N1 cells assessed as induction of calcium flux by FLIPR assay | J Med Chem 53: 2562-76 (2010) Article DOI: 10.1021/jm9018542 BindingDB Entry DOI: 10.7270/Q20C4VVG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50308552 ((1'S,2'R,3'S,4'R,5'S)-4-(6-Amino-2-chloro-9H-purin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.89 | n/a | n/a | n/a | n/a |
National Institutes of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Agonist activity at human P2Y1 receptor expressed in human 1321N1 cells by PLC assay | J Med Chem 53: 2562-76 (2010) Article DOI: 10.1021/jm9018542 BindingDB Entry DOI: 10.7270/Q20C4VVG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50118242 (((2R,3S,4R,5R)-5-(6-amino-2-(methylthio)-9H-purin-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 10.3 | n/a | n/a | n/a | n/a |
National Institutes of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Activation of human P2Y1 receptor expressed in human 1321N1 cells assessed as induction of calcium flux by FLIPR assay | J Med Chem 53: 2562-76 (2010) Article DOI: 10.1021/jm9018542 BindingDB Entry DOI: 10.7270/Q20C4VVG | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
