Affinity Data by PubMed id=20219369

PubMed code 20219369

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone-lysine N-methyltransferase SETD7 (Homo sapiens (Human))	BDBM50378739 (SINEFUNGIN \| jm2c00120, Sinefungin) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Park Curated by ChEMBL					Assay Description Inhibition of GST-fused human recombinant SET7 after 90 mins by SDS-PAGE based scintillation counting				Bioorg Med Chem Lett 20: 2103-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.069 BindingDB Entry DOI: 10.7270/Q2WQ04SW
University Park Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50314945 ((S)-4-((4-(amino(iminio)methylamino)butyl)(((2R,3S...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Park Curated by ChEMBL					Assay Description Inhibition of GST-fused human recombinant PRMT1 after 90 mins by SDS-PAGE based scintillation counting				Bioorg Med Chem Lett 20: 2103-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.069 BindingDB Entry DOI: 10.7270/Q2WQ04SW
University Park Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50314946 ((S)-4-((5-(amino(iminio)methylamino)pentyl)(((2R,3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Park Curated by ChEMBL					Assay Description Inhibition of GST-fused human recombinant PRMT1 after 90 mins by SDS-PAGE based scintillation counting				Bioorg Med Chem Lett 20: 2103-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.069 BindingDB Entry DOI: 10.7270/Q2WQ04SW
University Park Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50314944 ((S)-4-((3-(amino(iminio)methylamino)propyl)(((2R,3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Park Curated by ChEMBL					Assay Description Inhibition of GST-fused human recombinant PRMT1 after 90 mins by SDS-PAGE based scintillation counting				Bioorg Med Chem Lett 20: 2103-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.069 BindingDB Entry DOI: 10.7270/Q2WQ04SW
University Park Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University Park Curated by ChEMBL					Assay Description Inhibition of GST-fused human recombinant PRMT1 after 90 mins by SDS-PAGE based scintillation counting				Bioorg Med Chem Lett 20: 2103-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.069 BindingDB Entry DOI: 10.7270/Q2WQ04SW
University Park Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%