Affinity Data by PubMed id=20233015

PubMed code 20233015

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine \| 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	8.0	30
Brno University of Technology					Assay Description The assay was carried out according to the Ellman method [Ellman et al., Biochem. Pharmacol., 7:88-95], optimized for 96-well microplates using a Tec...				J Enzyme Inhib Med Chem 25: 414-20 (2010) Article DOI: 10.3109/14756360903213481 BindingDB Entry DOI: 10.7270/Q2PK0F2Z
Brno University of Technology					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine \| 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	8.0	30
Brno University of Technology					Assay Description The assay was carried out according to the Ellman method [Ellman et al., Biochem. Pharmacol., 7:88-95], optimized for 96-well microplates using a Tec...				J Enzyme Inhib Med Chem 25: 414-20 (2010) Article DOI: 10.3109/14756360903213481 BindingDB Entry DOI: 10.7270/Q2PK0F2Z
Brno University of Technology					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM10404 ((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	8.0	30
Brno University of Technology					Assay Description The assay was carried out according to the Ellman method [Ellman et al., Biochem. Pharmacol., 7:88-95], optimized for 96-well microplates using a Tec...				J Enzyme Inhib Med Chem 25: 414-20 (2010) Article DOI: 10.3109/14756360903213481 BindingDB Entry DOI: 10.7270/Q2PK0F2Z
Brno University of Technology					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM233116 (Nostotrebin 6) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	8.0	30
Brno University of Technology					Assay Description The assay was carried out according to the Ellman method [Ellman et al., Biochem. Pharmacol., 7:88-95], optimized for 96-well microplates using a Tec...				J Enzyme Inhib Med Chem 25: 414-20 (2010) Article DOI: 10.3109/14756360903213481 BindingDB Entry DOI: 10.7270/Q2PK0F2Z
Brno University of Technology					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM233116 (Nostotrebin 6) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	8.0	30
Brno University of Technology					Assay Description The assay was carried out according to the Ellman method [Ellman et al., Biochem. Pharmacol., 7:88-95], optimized for 96-well microplates using a Tec...				J Enzyme Inhib Med Chem 25: 414-20 (2010) Article DOI: 10.3109/14756360903213481 BindingDB Entry DOI: 10.7270/Q2PK0F2Z
Brno University of Technology					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM10404 ((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.33E+4	n/a	n/a	n/a	n/a	8.0	30
Brno University of Technology					Assay Description The assay was carried out according to the Ellman method [Ellman et al., Biochem. Pharmacol., 7:88-95], optimized for 96-well microplates using a Tec...				J Enzyme Inhib Med Chem 25: 414-20 (2010) Article DOI: 10.3109/14756360903213481 BindingDB Entry DOI: 10.7270/Q2PK0F2Z
Brno University of Technology					More data for this Ligand-Target Pair

* indicates data uncertainty>20%