Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM50317647 ((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC3 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50317647 ((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC1 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 2 (Homo sapiens (Human)) | BDBM50317647 ((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC2 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM50317649 (6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC6 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM50317647 ((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC6 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50317649 (6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of human HDAC4 catalytic domain expressed in Escherichia coli BL21 after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50317648 (6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC1 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50317650 (6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of human HDAC4 catalytic domain expressed in Escherichia coli BL21 after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 2 (Homo sapiens (Human)) | BDBM50317648 (6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC2 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM50317648 (6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC3 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 8 (Homo sapiens (Human)) | BDBM50317648 (6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of human full length HDAC8 expressed in Escherichia coli after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM50317650 (6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC6 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 8 (Homo sapiens (Human)) | BDBM50317650 (6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of human full length HDAC8 expressed in Escherichia coli after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 5 (Homo sapiens (Human)) | BDBM50317649 (6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of HDAC5 catalytic domain expressed in Escherichia coli after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 5 (Homo sapiens (Human)) | BDBM50317650 (6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of HDAC5 catalytic domain expressed in Escherichia coli after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM50317648 (6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC6 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50317650 (6-((3S,6S,9S,14aR)-3,9-bis((1H-indol-3-yl)methyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno Curated by ChEMBL | Assay Description Inhibition of full length HDAC1 expressed in HEK293 cells after 15 mins by fluorescence assay | Bioorg Med Chem 18: 3252-60 (2010) Article DOI: 10.1016/j.bmc.2010.03.022 BindingDB Entry DOI: 10.7270/Q2BC3ZP6 | |||||||||||
More data for this Ligand-Target Pair |