Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50320700 (1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(3-fluoroph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Inhibition of histidine-tagged human recombinant SRC expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50320700 (1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(3-fluoroph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Inhibition of histidine-tagged human recombinant SRC expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50230100 (4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50230100 (4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50230100 (4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Mixed-type inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins b... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50230100 (4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Inhibition of histidine-tagged human recombinant SRC expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50230100 (4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Inhibition of histidine-tagged human recombinant SRC expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50320700 (1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(3-fluoroph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50320700 (1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(3-fluoroph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50320700 (1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(3-fluoroph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Genetics IGM-CNR Curated by ChEMBL | Assay Description Mixed-type inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins b... | Bioorg Med Chem 18: 3999-4008 (2010) Article DOI: 10.1016/j.bmc.2010.04.024 BindingDB Entry DOI: 10.7270/Q2Q240F5 | |||||||||||
More data for this Ligand-Target Pair |