Affinity Data by PubMed id=20481631

PubMed code 20481631

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50322414 (4-(4-Fluorophenyl)-5-{2-[4-hydroxycyclohexylamino]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tubingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 53: 4798-802 (2010) Article DOI: 10.1021/jm100161q BindingDB Entry DOI: 10.7270/Q2154H7H
Eberhard Karls University of Tubingen Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tubingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 53: 4798-802 (2010) Article DOI: 10.1021/jm100161q BindingDB Entry DOI: 10.7270/Q2154H7H
Eberhard Karls University of Tubingen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50322415 ((S)-4-(4-Fluorophenyl)-5-[2-(3-methylbutan-2-ylami...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tubingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 53: 4798-802 (2010) Article DOI: 10.1021/jm100161q BindingDB Entry DOI: 10.7270/Q2154H7H
Eberhard Karls University of Tubingen Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50322416 ((R)-4-(4-Fluorophenyl)-5-[2-(1-phenylethylamino)py...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tubingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 53: 4798-802 (2010) Article DOI: 10.1021/jm100161q BindingDB Entry DOI: 10.7270/Q2154H7H
Eberhard Karls University of Tubingen Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50322417 (4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1,3-dihydroimi...) Show SMILES Fc1ccc(cc1)-c1[nH]c(=O)[nH]c1-c1ccncc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	468	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tubingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 53: 4798-802 (2010) Article DOI: 10.1021/jm100161q BindingDB Entry DOI: 10.7270/Q2154H7H
Eberhard Karls University of Tubingen Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%