Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321586 (1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation counting | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321585 (1-(2-(2-tert-butylphenyl)benzofuran-7-yl)-3-(4-(tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation counting | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321584 (1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-(tri...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation counting | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321587 (1-(4-butoxyphenyl)-3-(2-(2-isopropylphenyl)benzofu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation counting | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321588 (1-(4-chlorophenyl)-3-(2-(2-isopropylphenyl)benzofu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation counting | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321583 (1-(4-(trifluoromethoxy)phenyl)-3-(2-(2-(trifluorom...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation counting | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321589 (1-(4-tert-butylphenyl)-3-(2-(2-isopropylphenyl)ben...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation counting | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321586 (1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321589 (1-(4-tert-butylphenyl)-3-(2-(2-isopropylphenyl)ben...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321593 (1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321587 (1-(4-butoxyphenyl)-3-(2-(2-isopropylphenyl)benzofu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321588 (1-(4-chlorophenyl)-3-(2-(2-isopropylphenyl)benzofu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321585 (1-(2-(2-tert-butylphenyl)benzofuran-7-yl)-3-(4-(tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321584 (1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-(tri...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321595 (1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(3-(tri...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321583 (1-(4-(trifluoromethoxy)phenyl)-3-(2-(2-(trifluorom...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321594 (1-(4-(dimethylamino)phenyl)-3-(2-(2-isopropylpheny...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321590 (1-(4-(trifluoromethoxy)phenyl)-3-(2-(3-(trifluorom...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321592 (1-(2-(2-isopropoxyphenyl)benzofuran-7-yl)-3-(4-(tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50321591 (1-(2-(2-chlorophenyl)benzofuran-7-yl)-3-(4-(triflu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assay | Bioorg Med Chem Lett 20: 4104-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.072 BindingDB Entry DOI: 10.7270/Q2HX1DNF | |||||||||||
More data for this Ligand-Target Pair |