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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Zinc finger protein GLI1 (Homo sapiens (Human)) | BDBM50321859 (2-(3-Benzoylphenyl)-N-(1H-indol-5-yl)-N-propylprop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Inhibition of human Gli1 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter ge... | Bioorg Med Chem 18: 4801-11 (2011) Article DOI: 10.1016/j.bmc.2010.05.001 BindingDB Entry DOI: 10.7270/Q23R0TTT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Zinc finger protein GLI1 (Homo sapiens (Human)) | BDBM50321858 (2-(3-Benzoylphenyl)-N-(1H-indol-6-yl)-N-propylprop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Inhibition of human Gli1 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter ge... | Bioorg Med Chem 18: 4801-11 (2011) Article DOI: 10.1016/j.bmc.2010.05.001 BindingDB Entry DOI: 10.7270/Q23R0TTT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Zinc finger protein GLI2 (Homo sapiens (Human)) | BDBM50321859 (2-(3-Benzoylphenyl)-N-(1H-indol-5-yl)-N-propylprop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Inhibition of human Gli2 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter ge... | Bioorg Med Chem 18: 4801-11 (2011) Article DOI: 10.1016/j.bmc.2010.05.001 BindingDB Entry DOI: 10.7270/Q23R0TTT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Zinc finger protein GLI2 (Homo sapiens (Human)) | BDBM50321858 (2-(3-Benzoylphenyl)-N-(1H-indol-6-yl)-N-propylprop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Inhibition of human Gli2 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter ge... | Bioorg Med Chem 18: 4801-11 (2011) Article DOI: 10.1016/j.bmc.2010.05.001 BindingDB Entry DOI: 10.7270/Q23R0TTT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Zinc finger protein GLI1 (Homo sapiens (Human)) | BDBM50249557 (2,2'-(2-(pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Inhibition of human Gli1-mediated transcriptional activity in human Rh30 cells after 24 hrs by luciferase reporter gene assay | Bioorg Med Chem 18: 4801-11 (2011) Article DOI: 10.1016/j.bmc.2010.05.001 BindingDB Entry DOI: 10.7270/Q23R0TTT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
