Affinity Data by PubMed id=20681583

PubMed code 20681583

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50326197 (1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...) Show SMILES Cn1c2nc(=O)n(C)c(N)c2[nH]c1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	497	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Binding affinity to adrenergic alpha1D receptor				J Med Chem 53: 6089-99 (2010) Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50326197 (1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...) Show SMILES Cn1c2nc(=O)n(C)c(N)c2[nH]c1=O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	758	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Binding affinity to adrenergic alpha1B receptor				J Med Chem 53: 6089-99 (2010) Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50326197 (1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...) Show SMILES Cn1c2nc(=O)n(C)c(N)c2[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	885	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Binding affinity to adrenergic alpha1A receptor				J Med Chem 53: 6089-99 (2010) Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50326197 (1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...) Show SMILES Cn1c2nc(=O)n(C)c(N)c2[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Binding affinity to kappa opioid receptor				J Med Chem 53: 6089-99 (2010) Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1E (Homo sapiens (Human))	BDBM50326197 (1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...) Show SMILES Cn1c2nc(=O)n(C)c(N)c2[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Binding affinity to 5HT1E receptor				J Med Chem 53: 6089-99 (2010) Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Homo sapiens (Human))	BDBM50326197 (1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...) Show SMILES Cn1c2nc(=O)n(C)c(N)c2[nH]c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Binding affinity to nicotinic alpha3beta2 receptor receptor				J Med Chem 53: 6089-99 (2010) Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50326197 (1,9-dimethyl-2,8-dioxo-2,3,8,9-tetrahydro-1H-purin...) Show SMILES Cn1c2nc(=O)n(C)c(N)c2[nH]c1=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor				J Med Chem 53: 6089-99 (2010) Article DOI: 10.1021/jm100490m BindingDB Entry DOI: 10.7270/Q2GX4BS7
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%