Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50326284 (1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50326280 (1-(beta-D-Glucopyranosyl)-4-chloro-3-(5-chloro-2-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20877 (3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50326283 (1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50326279 (1-(beta-D-Glucopyranosyl)-3-(5-ethyl-2-thienylmeth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50326282 (1-(beta-D-Glucopyranosyl)-4-chloro-3-(2-ethyl-5-py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50326281 (1-(beta-D-Glucopyranosyl)-4-chloro-3-(1-phenyl-1H-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20877 (3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50326284 (1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50326278 (1-(beta-D-Glucopyranosyl)-3-(5-ethyl-2-furylmethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint... | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 2, facilitated glucose transporter member 1 (Rattus norvegicus) | BDBM50326284 (1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of GLUT1-mediated [3H]2-deoxy-glucose uptake in rat L6 cells after 15 mins by liquid scintillation counting | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 2, facilitated glucose transporter member 1 (Rattus norvegicus) | BDBM20877 (3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of GLUT1-mediated [3H]2-deoxy-glucose uptake in rat L6 cells after 15 mins by liquid scintillation counting | J Med Chem 53: 6355-60 (2010) Article DOI: 10.1021/jm100332n BindingDB Entry DOI: 10.7270/Q2V69JSS | |||||||||||
More data for this Ligand-Target Pair |