Affinity Data by PubMed id=20797617

PubMed code 20797617

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Disulfide bond formation protein B (Escherichia coli)	BDBM81417 (Fragment 1) Show SMILES CC1=C2CC(CCC2(C)CCC1=O)C(C)(C)O \|c:1\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	6.2	30
Leiden University					Assay Description 13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...				Chem Biol 17: 881-91 (2010) Article DOI: 10.1016/j.chembiol.2010.06.011 BindingDB Entry DOI: 10.7270/Q2M90740
Leiden University					More data for this Ligand-Target Pair
Disulfide bond formation protein B (Escherichia coli)	BDBM41732 (1-benzyl-2,5-dimethyl-pyrrole-3-carboxylic acid \| ...) Show SMILES Cc1cc(C(O)=O)c(C)n1Cc1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	6.2	30
Leiden University					Assay Description 13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...				Chem Biol 17: 881-91 (2010) Article DOI: 10.1016/j.chembiol.2010.06.011 BindingDB Entry DOI: 10.7270/Q2M90740
Leiden University					More data for this Ligand-Target Pair
Disulfide bond formation protein B (Escherichia coli)	BDBM50042278 (7-Chloro-1H-quinoline-2,4-dione \| CHEMBL112809 \| F...) Show SMILES Oc1cc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	6.2	30
Leiden University					Assay Description 13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...				Chem Biol 17: 881-91 (2010) Article DOI: 10.1016/j.chembiol.2010.06.011 BindingDB Entry DOI: 10.7270/Q2M90740
Leiden University					More data for this Ligand-Target Pair
Disulfide bond formation protein B (Escherichia coli)	BDBM81420 (Fragment 6) Show SMILES OC(=O)C1CCN(CC1)C(=O)c1scc2OCCOc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	6.2	30
Leiden University					Assay Description 13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...				Chem Biol 17: 881-91 (2010) Article DOI: 10.1016/j.chembiol.2010.06.011 BindingDB Entry DOI: 10.7270/Q2M90740
Leiden University					More data for this Ligand-Target Pair
Disulfide bond formation protein B (Escherichia coli)	BDBM81418 (Fragment 2) Show SMILES CCC(=O)C1C(=O)CC(C)(C)C(C1=O)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	6.2	30
Leiden University					Assay Description 13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...				Chem Biol 17: 881-91 (2010) Article DOI: 10.1016/j.chembiol.2010.06.011 BindingDB Entry DOI: 10.7270/Q2M90740
Leiden University					More data for this Ligand-Target Pair
Disulfide bond formation protein B (Escherichia coli)	BDBM81421 (Fragment 7) Show SMILES Cc1ccc2scc(CC(O)=O)c2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.15E+5	n/a	n/a	n/a	n/a	6.2	30
Leiden University					Assay Description 13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...				Chem Biol 17: 881-91 (2010) Article DOI: 10.1016/j.chembiol.2010.06.011 BindingDB Entry DOI: 10.7270/Q2M90740
Leiden University					More data for this Ligand-Target Pair
Disulfide bond formation protein B (Escherichia coli)	BDBM42347 ((2,2-dimethyl-4-oxo-3,4-dihydro-1,5-benzothiazepin...) Show SMILES CC1(C)CC(=O)N(CC(O)=O)c2ccccc2S1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.68E+5	n/a	n/a	n/a	n/a	6.2	30
Leiden University					Assay Description 13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...				Chem Biol 17: 881-91 (2010) Article DOI: 10.1016/j.chembiol.2010.06.011 BindingDB Entry DOI: 10.7270/Q2M90740
Leiden University					More data for this Ligand-Target Pair
Disulfide bond formation protein B (Escherichia coli)	BDBM81419 (Fragment 3) Show SMILES Oc1ccc(NC(=O)COc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.93E+5	n/a	n/a	n/a	n/a	6.2	30
Leiden University					Assay Description 13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...				Chem Biol 17: 881-91 (2010) Article DOI: 10.1016/j.chembiol.2010.06.011 BindingDB Entry DOI: 10.7270/Q2M90740
Leiden University					More data for this Ligand-Target Pair

* indicates data uncertainty>20%