Affinity Data by PubMed id=20822901

PubMed code 20822901

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM26106 (CHEMBL90852 \| N-oxalyl glycine, 1a \| NOG \| Oxalylg...) Show SMILES OC(=O)CNC(=O)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	842	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of PHD1 by HTRF assay				Bioorg Med Chem Lett 20: 6125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.032 BindingDB Entry DOI: 10.7270/Q22B8Z7F
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM26110 (N,3-dihydroxybenzamide \| aromatic hydroxamic acid,...) Show SMILES ONC(=O)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of PHD1 by HTRF assay				Bioorg Med Chem Lett 20: 6125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.032 BindingDB Entry DOI: 10.7270/Q22B8Z7F
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50328019 (2-(3-hydroxypicolinamido)acetic acid \| CHEMBL12565...) Show SMILES OC(=O)CNC(=O)c1ncccc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	9.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of PHD1 by HTRF assay				Bioorg Med Chem Lett 20: 6125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.032 BindingDB Entry DOI: 10.7270/Q22B8Z7F
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50328018 (2-(3-hydroxyphenyl)-2-mercaptoacetic acid \| CHEMBL...) Show SMILES OC(=O)C(S)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of PHD1 by HTRF assay				Bioorg Med Chem Lett 20: 6125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.032 BindingDB Entry DOI: 10.7270/Q22B8Z7F
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM26113 (2,4 PDCA \| cid_10365 \| pyridine carboxylate, 6a \| ...) Show SMILES OC(=O)c1ccnc(c1)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	6.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of PHD1 by HTRF assay				Bioorg Med Chem Lett 20: 6125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.032 BindingDB Entry DOI: 10.7270/Q22B8Z7F
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50328021 ((2-Hydroxy-benzoylamino)-acetic acid \| 2-(2-hydrox...) Show SMILES OC(=O)CNC(=O)c1ccccc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of PHD1 by HTRF assay				Bioorg Med Chem Lett 20: 6125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.032 BindingDB Entry DOI: 10.7270/Q22B8Z7F
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50328020 (2-(picolinamido)acetic acid \| CHEMBL221255) Show SMILES OC(=O)CNC(=O)c1ccccn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of PHD1 by HTRF assay				Bioorg Med Chem Lett 20: 6125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.032 BindingDB Entry DOI: 10.7270/Q22B8Z7F
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50328017 (2-(3-HYDROXYPHENYL)-2-OXO-ETHANOIC ACID \| 2-(3-hyd...) Show SMILES OC(=O)C(=O)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of PHD1 by HTRF assay				Bioorg Med Chem Lett 20: 6125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.032 BindingDB Entry DOI: 10.7270/Q22B8Z7F
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%