Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328509 (2-Amino-4-methyl-7-(naphthalen-1-yl)-5-oxo-5,6,7,8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50292997 (2-Amino-4-(4-methoxyphenyl)-7-(naphthalene-1-yl)-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328508 (2-Amino-4-(4-methoxyphenyl)-7-(naphthalene-2-yl)-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328510 (2-Amino-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50292986 (2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328507 (2-Amino-7-benzyl-4-(4-methoxyphenyl)-5-oxo-5,6,7,8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50292990 (2-amino-4-methyl-5-oxo-7-phenyl-5,6,7,8-tetrahydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328512 (CHEMBL1259025 | tert-Butyl2-Amino-5-oxo-4,7-diphen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328513 (2-Amino-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328516 (CHEMBL1259064 | N-(3-Cyano-5-oxo-4,7-diphenyl-5,6,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328517 (5-oxo-4,7-Diphenyl-5,6,7,8-tetrahydro-4H-chromene-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328514 (2-Amino-4,7-diphenyl-7,8-dihydro-4H-chromen-5(6H)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328511 (CHEMBL1259008 | Methyl2-Amino-5-oxo-4,7-diphenyl-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328520 (CHEMBL1259099 | syn-2-Amino-5-oxo-4,7-diphenyl-4,5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328521 (CHEMBL1259100 | anti-2-Amino-5-oxo-4,7-diphenyl-4,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50292989 (2-Amino-5-oxo-7-phenyl-5,6,7,8-tetrahydro-4H-chrom...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328518 (CHEMBL1259081 | syn-2-amino-5-oxo-4,7-diphenyl-5,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50292987 (2-amino-4-(2-fluorophenyl)-5-oxo-5,6,7,8-tetrahydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328519 (CHEMBL1259082 | anti-2-Amino-5-oxo-4,7-diphenyl-5,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.16E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50292988 (2-amino-4-(benzo[d][1,3]dioxol-5-yl)-7-methyl-5-ox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.16E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50328515 ((E)-Ethyl N-3-Cyano-5-oxo-4,7-diphenyl-5,6,7,8-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assay | J Med Chem 53: 7180-91 (2010) Article DOI: 10.1021/jm1009154 BindingDB Entry DOI: 10.7270/Q2VM4CGX | |||||||||||
More data for this Ligand-Target Pair |