Affinity Data by PubMed id=20951473

PubMed code 20951473

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332931 (1-[4-(1,1-Dioxo-1H-1lambda-6-naphtho[1,8-cd]isothi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332938 (5-Bromo-1-[4-(2,2-dioxo-4,5-dihydro-3H-2lambda-6-t...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332930 (5-methyl-1-(4-(2-oxobenzo[cd]indol-1(2H)-yl)but-2-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332937 (1-[4-(2,2-Dioxo-4,5-dihydro-3H-2lambda-6-thia-1,2a...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332935 (CHEMBL1631395 \| N-(1-(4-(5-methyl-2,4-dioxo-3,4-di...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332932 (5-methyl-1-(4-(2-oxo-2,4,5,6-tetrahydro-1H-imidazo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332936 (1-(4-(8-amino-2-oxo-2,4,5,6-tetrahydro-1H-imidazo[...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332929 (((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-di...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332933 (CHEMBL1631396 \| N-(1-(4-(5-methyl-2,4-dioxo-3,4-di...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50332934 (1-(4-(5-amino-2-oxo-2,4,5,6-tetrahydro-1H-imidazo[...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Thymidine monophosphate kinase by spectrophotometry				Eur J Med Chem 45: 5910-8 (2010) Article DOI: 10.1016/j.ejmech.2010.09.056 BindingDB Entry DOI: 10.7270/Q2PN95WH
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%