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PubMed code 21030257

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Signal transducer and activator of transcription 3


(Homo sapiens (Human))
BDBM50331576
PNG
(4-(pyrrolidin-1-ylsulfonyl)-N-(thiophen-2-ylmethyl...)
Show SMILES Cc1ccc(cc1)-c1sc(cc1S(=O)(=O)N1CCCC1)C(=O)NCc1cccs1
Show InChI InChI=1S/C21H22N2O3S3/c1-15-6-8-16(9-7-15)20-19(29(25,26)23-10-2-3-11-23)13-18(28-20)21(24)22-14-17-5-4-12-27-17/h4-9,12-13H,2-3,10-11,14H2,1H3,(H,22,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.50E+4n/an/an/an/a



University of London

Curated by ChEMBL


Assay Description
Inhibition of STAT3 in human HeLa cells by luciferase reporter assay


Bioorg Med Chem Lett 20: 7029-32 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.117
BindingDB Entry DOI: 10.7270/Q2VQ32XP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%