Found 60 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334916
(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334920
((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3/t16-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334918
((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2/t14-/m1/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334920
((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3/t16-/m1/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334917
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334917
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334767
((2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)Show SMILES CN[C@@H]1C[C@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C17H17Cl2N/c1-20-13-8-11-4-2-3-5-14(11)15(10-13)12-6-7-16(18)17(19)9-12/h2-7,9,13,15,20H,8,10H2,1H3/t13-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334767
((2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)Show SMILES CN[C@@H]1C[C@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C17H17Cl2N/c1-20-13-8-11-4-2-3-5-14(11)15(10-13)12-6-7-16(18)17(19)9-12/h2-7,9,13,15,20H,8,10H2,1H3/t13-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334925
((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CN(c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-12-8-11-4-2-3-5-16(11)20(10-12)13-6-7-14(17)15(18)9-13/h2-7,9,12,19H,8,10H2,1H3/t12-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50334925
((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CN(c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-12-8-11-4-2-3-5-16(11)20(10-12)13-6-7-14(17)15(18)9-13/h2-7,9,12,19H,8,10H2,1H3/t12-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334767
((2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)Show SMILES CN[C@@H]1C[C@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C17H17Cl2N/c1-20-13-8-11-4-2-3-5-14(11)15(10-13)12-6-7-16(18)17(19)9-12/h2-7,9,13,15,20H,8,10H2,1H3/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334918
((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2/t14-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334922
(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)14-9-12-5-3-4-6-17(12)21(11-14)13-7-8-15(18)16(19)10-13/h3-8,10,14H,9,11H2,1-2H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 122 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334925
((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CN(c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-12-8-11-4-2-3-5-16(11)20(10-12)13-6-7-14(17)15(18)9-13/h2-7,9,12,19H,8,10H2,1H3/t12-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334918
((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2/t14-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334923
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-12-8-11-4-2-3-5-16(11)20(10-12)13-6-7-14(17)15(18)9-13/h2-7,9,12,19H,8,10H2,1H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 177 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334915
(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 246 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50334920
((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334926
((S)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CN(c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)14-9-12-5-3-4-6-17(12)21(11-14)13-7-8-15(18)16(19)10-13/h3-8,10,14H,9,11H2,1-2H3/t14-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 309 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334922
(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)14-9-12-5-3-4-6-17(12)21(11-14)13-7-8-15(18)16(19)10-13/h3-8,10,14H,9,11H2,1-2H3 | PDB
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| n/a | n/a | 436 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334924
((S)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-13-6-5-12(8-14(13)17)19-9-11(18)7-10-3-1-2-4-15(10)19/h1-6,8,11H,7,9,18H2/t11-/m0/s1 | NCI pathway
Reactome pathway
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| n/a | n/a | 465 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | Reactome pathway
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| n/a | n/a | 601 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334921
(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)Show InChI InChI=1S/C15H14Cl2N2/c16-13-6-5-12(8-14(13)17)19-9-11(18)7-10-3-1-2-4-15(10)19/h1-6,8,11H,7,9,18H2 | NCI pathway
Reactome pathway
KEGG
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| n/a | n/a | 605 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334915
(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2 | PDB
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| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334915
(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2 | Reactome pathway
KEGG
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| n/a | n/a | 926 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334917
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3 | Reactome pathway
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| n/a | n/a | 934 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334923
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-12-8-11-4-2-3-5-16(11)20(10-12)13-6-7-14(17)15(18)9-13/h2-7,9,12,19H,8,10H2,1H3 | PDB
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| n/a | n/a | 985 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334923
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-12-8-11-4-2-3-5-16(11)20(10-12)13-6-7-14(17)15(18)9-13/h2-7,9,12,19H,8,10H2,1H3 | Reactome pathway
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| n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334920
((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3/t16-/m1/s1 | Reactome pathway
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| n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334925
((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CN(c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-12-8-11-4-2-3-5-16(11)20(10-12)13-6-7-14(17)15(18)9-13/h2-7,9,12,19H,8,10H2,1H3/t12-/m0/s1 | Reactome pathway
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| n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB
UniProtKB/SwissProt
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| CHEMBL
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| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334924
((S)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-13-6-5-12(8-14(13)17)19-9-11(18)7-10-3-1-2-4-15(10)19/h1-6,8,11H,7,9,18H2/t11-/m0/s1 | Reactome pathway
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| n/a | n/a | 1.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334922
(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)14-9-12-5-3-4-6-17(12)21(11-14)13-7-8-15(18)16(19)10-13/h3-8,10,14H,9,11H2,1-2H3 | Reactome pathway
KEGG
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| n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334924
((S)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-13-6-5-12(8-14(13)17)19-9-11(18)7-10-3-1-2-4-15(10)19/h1-6,8,11H,7,9,18H2/t11-/m0/s1 | PDB
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| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334921
(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)Show InChI InChI=1S/C15H14Cl2N2/c16-13-6-5-12(8-14(13)17)19-9-11(18)7-10-3-1-2-4-15(10)19/h1-6,8,11H,7,9,18H2 | PDB
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| n/a | n/a | 2.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334921
(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)Show InChI InChI=1S/C15H14Cl2N2/c16-13-6-5-12(8-14(13)17)19-9-11(18)7-10-3-1-2-4-15(10)19/h1-6,8,11H,7,9,18H2 | Reactome pathway
KEGG
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| CHEMBL
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Similars
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| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50334917
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334926
((S)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CN(c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)14-9-12-5-3-4-6-17(12)21(11-14)13-7-8-15(18)16(19)10-13/h3-8,10,14H,9,11H2,1-2H3/t14-/m0/s1 | Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human ERG |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50334918
((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human ERG |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50334918
((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2/t14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334916
(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334926
((S)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CN(c2ccc(Cl)c(Cl)c2)c2ccccc2C1 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)14-9-12-5-3-4-6-17(12)21(11-14)13-7-8-15(18)16(19)10-13/h3-8,10,14H,9,11H2,1-2H3/t14-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50334920
((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3/t16-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334916
(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50334917
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human ERG |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50334920
((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of human ERG |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50334917
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C19 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C19 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50334918
((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50334920
((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50334918
((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C19 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50334917
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50334920
((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)Show SMILES CN(C)[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C17H18Cl2N2/c1-20(2)16-9-10-21(17-6-4-3-5-13(16)17)12-7-8-14(18)15(19)11-12/h3-8,11,16H,9-10H2,1-2H3/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C19 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50334918
((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)Show InChI InChI=1S/C15H14Cl2N2/c16-12-6-5-10(9-13(12)17)19-8-7-14(18)11-3-1-2-4-15(11)19/h1-6,9,14H,7-8,18H2/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50334917
(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086
BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this
Ligand-Target Pair | |
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