Affinity Data by PubMed id=21145738

PubMed code 21145738

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50334369 (3-(4-(Dimethylamino)phenyl)-1-(4-iodophenyl)-2-pro...) Show SMILES CN(C)c1ccc(cc1)C#CC(=O)c1ccc(I)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma counting				Bioorg Med Chem Lett 21: 117-20 (2010) Article DOI: 10.1016/j.bmcl.2010.11.058 BindingDB Entry DOI: 10.7270/Q2N87B2Z
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50334371 (3-(4-Methoxyphenyl)-1-(4-iodophenyl)-2-propyn-1-on...) Show SMILES COc1ccc(cc1)C#CC(=O)c1ccc(I)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma counting				Bioorg Med Chem Lett 21: 117-20 (2010) Article DOI: 10.1016/j.bmcl.2010.11.058 BindingDB Entry DOI: 10.7270/Q2N87B2Z
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50334370 (3-(4-(Dimethylamino)phenyl)-1-(4-fruorophenyl)-2-p...) Show SMILES CN(C)c1ccc(cc1)C#CC(=O)c1ccc(F)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma counting				Bioorg Med Chem Lett 21: 117-20 (2010) Article DOI: 10.1016/j.bmcl.2010.11.058 BindingDB Entry DOI: 10.7270/Q2N87B2Z
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122787 (2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...) Show SMILES CN(C)c1ccc(cc1)-c1cn2cc(I)ccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma counting				Bioorg Med Chem Lett 21: 117-20 (2010) Article DOI: 10.1016/j.bmcl.2010.11.058 BindingDB Entry DOI: 10.7270/Q2N87B2Z
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50334372 (3-(4-Hydroxyphenyl)-1-(4-iodophenyl)-2-propyn-1-on...) Show SMILES Oc1ccc(cc1)C#CC(=O)c1ccc(I)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	326	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma counting				Bioorg Med Chem Lett 21: 117-20 (2010) Article DOI: 10.1016/j.bmcl.2010.11.058 BindingDB Entry DOI: 10.7270/Q2N87B2Z
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%