Affinity Data by PubMed id=21280624

PubMed code 21280624

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50339190 (CHEMBL443683 \| telomestatin) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi La Sapienza Curated by ChEMBL					Assay Description Inhibition of human Telomerase activity in cell free system by TRAP assay				J Med Chem 54: 1140-56 (2011) Article DOI: 10.1021/jm1013665 BindingDB Entry DOI: 10.7270/Q2GB24CR
Universita` degli Studi La Sapienza Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50339188 (CHEMBL1689442 \| N,N'-Bis[2-(1-piperidino)-ethyl]-1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi La Sapienza Curated by ChEMBL					Assay Description Inhibition of human Telomerase activity in cell free system by TRAP assay				J Med Chem 54: 1140-56 (2011) Article DOI: 10.1021/jm1013665 BindingDB Entry DOI: 10.7270/Q2GB24CR
Universita` degli Studi La Sapienza Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50339187 (CHEMBL1689438 \| N,N'-Bis(5-(1-piperidino)-3-oxapen...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi La Sapienza Curated by ChEMBL					Assay Description Inhibition of human Telomerase activity in cell free system by TRAP assay				J Med Chem 54: 1140-56 (2011) Article DOI: 10.1021/jm1013665 BindingDB Entry DOI: 10.7270/Q2GB24CR
Universita` degli Studi La Sapienza Curated by ChEMBL					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50339189 (CHEMBL1689441 \| N,N'-Bis[2-(1-piperidino)-ethyl]-1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi La Sapienza Curated by ChEMBL					Assay Description Inhibition of human Telomerase activity in cell free system by TRAP assay				J Med Chem 54: 1140-56 (2011) Article DOI: 10.1021/jm1013665 BindingDB Entry DOI: 10.7270/Q2GB24CR
Universita` degli Studi La Sapienza Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%