Affinity Data by PubMed id=21295470

PubMed code 21295470

Found 27 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337581 (CHEMBL1682993 \| rac-N1-(1-(4-Methylpyridin-2-yl)et...) Show SMILES CC(N(CCCCN)Cc1ncccc1C)c1cc(C)ccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337584 ((S)-N1-((3-aminopyridin-2-yl)methyl)-N1-(5,6,7,8-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10.9	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Displacement of [125I]SDF-1alpha from CXCR4 in human CEM-CCRF cells by liquid scintillation counting				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337585 ((S)-N1-((1H-benzo[d]imidazol-2-yl)methyl)-N1-(1-(p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	16.6	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Displacement of [125I]SDF-1alpha from CXCR4 in human CEM-CCRF cells by liquid scintillation counting				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337561 (CHEMBL1682854 \| rac-N1-(3-methylpyridin-2-ylmethyl...) Show SMILES Cc1cccnc1CN(CCCCN)C1CCCc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337577 (CHEMBL1682989 \| rac-N1-(3-iso-Butylpyridin-2-ylmet...) Show SMILES CC(N(CCCCN)Cc1ncccc1C(C)(C)C)c1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337566 (CHEMBL1682859 \| rac-N'-(3,5-Dimethylpyridin-2-ylme...) Show SMILES Cc1cnc(CN(CCCCN)C2CCCc3cccnc23)c(C)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337580 (CHEMBL1682992 \| rac-N1-(3,5-dimethylpyridin-2-ylme...) Show SMILES CC(N(CCCCN)Cc1ncc(C)cc1C)c1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337574 (CHEMBL1682986 \| racN1-(3-Methylpyridin-2-ylmethyl)...) Show SMILES CC(N(CCCCN)Cc1ncccc1C)c1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337570 (CHEMBL1682863 \| rac-N1-(3-Aminopyridin-2-ylmethyl)...) Show SMILES NCCCCN(Cc1ncccc1N)C1CCCc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337563 (CHEMBL1682856 \| rac-N1-(4-Methylpyridin-2-ylmethyl...) Show SMILES Cc1ccc(CN(CCCCN)C2CCCc3cccnc23)nc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337586 ((S)-N1-((3-methylpyridin-2-yl)methyl)-N1-(1-(pyrid...) Show SMILES C[C@H](N(CCCCN)Cc1ncccc1C)c1ccccn1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35.8	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Displacement of [125I]SDF-1alpha from CXCR4 in human CEM-CCRF cells by liquid scintillation counting				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337565 (CHEMBL1682858 \| rac-N1-((4,6-dimethylpyridin-2-yl)...) Show SMILES Cc1cc(C)nc(CN(CCCCN)C2CCCc3cccnc23)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337573 (CHEMBL1682866 \| racN1-(3-chloropyridin-2-ylmethyl)...) Show SMILES NCCCCN(Cc1ncccc1Cl)C1CCCc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337567 (CHEMBL1682860 \| rac-N1-(6-aminopyridin-2-ylmethyl)...) Show SMILES NCCCCN(Cc1cccc(N)n1)C1CCCc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337564 (CHEMBL1682857 \| rac-N1-(6-Methylpyridin-2-ylmethyl...) Show SMILES Cc1cccc(CN(CCCCN)C2CCCc3cccnc23)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337583 ((S)-N1-((3,5-dimethylpyridin-2-yl)methyl)-N1-(5,6,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	62.9	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Displacement of [125I]SDF-1alpha from CXCR4 in human CEM-CCRF cells by liquid scintillation counting				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337571 (CHEMBL1682864 \| rac-N1-(3-isopropylpyridin-2-ylmet...) Show SMILES CC(C)c1cccnc1CN(CCCCN)C1CCCc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337578 (CHEMBL1682990 \| rac-N1-((5-methylpyridin-2-yl)meth...) Show SMILES CC(N(CCCCN)Cc1ccc(C)cn1)c1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337575 (CHEMBL1682987 \| rac-N1-((3-aminopyridin-2-yl)methy...) Show SMILES CC(N(CCCCN)Cc1ncccc1N)c1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337560 ((+/-)-N1-(pyridine-2-ylmethyl)-N1-(5,6,7,8-tetrahy...) Show SMILES NCCCCN(Cc1ccccn1)C1CCCc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337572 (CHEMBL1682865 \| rac-(2-(((4-Aminobutyl)-(5,6,7,8-t...) Show SMILES NCCCCN(Cc1ncccc1CO)C1CCCc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337562 (CHEMBL1682855 \| rac-N1-((4-methylpyridin-2-yl)meth...) Show SMILES Cc1ccnc(CN(CCCCN)C2CCCc3cccnc23)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337582 ((S)-N1-((6-methylpyridin-2-yl)methyl)-N1-(5,6,7,8-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96.1	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Displacement of [125I]SDF-1alpha from CXCR4 in human CEM-CCRF cells by liquid scintillation counting				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337576 (CHEMBL1682988 \| rac-N1-(1-(pyridin-2-yl)ethyl)-N1-...) Show SMILES CC(N(CCCCN)Cc1ncccc1C(F)(F)F)c1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337569 (CHEMBL1682862 \| rac-2-(((4-aminobutyl)(5,6,7,8-tet...) Show SMILES NCCCCN(Cc1ncccc1O)C1CCCc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337579 (CHEMBL1682991 \| rac-N1-((6-methylpyridin-2-yl)meth...) Show SMILES CC(N(CCCCN)Cc1cccc(C)n1)c1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50337568 (CHEMBL1682861 \| rac-N1-((6-(methoxymethyl)pyridin-...) Show SMILES COCc1cccc(CN(CCCCN)C2CCCc3cccnc23)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity at CXCR4 in human CEM-CCRF cells assessed as inhibition of SDF-1-induced calcium signaling				Bioorg Med Chem Lett 21: 1414-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.021 BindingDB Entry DOI: 10.7270/Q2FT8M9F
Genzyme Corp. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%