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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Veterinary and Pharmaceutical Sciences Brno Curated by ChEMBL | Assay Description Inhibition of ram seminal vesicle COX-1 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassay | J Nat Prod 74: 614-9 (2011) Article DOI: 10.1021/np100638h BindingDB Entry DOI: 10.7270/Q2Z89CRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50193718 (2-(2,4-dihydroxy-phenyl)-5-hydroxy-8,8-dimethyl-3-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Veterinary and Pharmaceutical Sciences Brno Curated by ChEMBL | Assay Description Inhibition of ram seminal vesicle COX-1 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassay | J Nat Prod 74: 614-9 (2011) Article DOI: 10.1021/np100638h BindingDB Entry DOI: 10.7270/Q2Z89CRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Veterinary and Pharmaceutical Sciences Brno Curated by ChEMBL | Assay Description Inhibition of human recombinant COX-2 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassay | J Nat Prod 74: 614-9 (2011) Article DOI: 10.1021/np100638h BindingDB Entry DOI: 10.7270/Q2Z89CRW | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50193718 (2-(2,4-dihydroxy-phenyl)-5-hydroxy-8,8-dimethyl-3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Veterinary and Pharmaceutical Sciences Brno Curated by ChEMBL | Assay Description Inhibition of human recombinant COX-2 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassay | J Nat Prod 74: 614-9 (2011) Article DOI: 10.1021/np100638h BindingDB Entry DOI: 10.7270/Q2Z89CRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50242014 (CHEMBL464006 | Morusin | Morusin, 3 | TCMDC-124149...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Veterinary and Pharmaceutical Sciences Brno Curated by ChEMBL | Assay Description Inhibition of human recombinant COX-2 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassay | J Nat Prod 74: 614-9 (2011) Article DOI: 10.1021/np100638h BindingDB Entry DOI: 10.7270/Q2Z89CRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50242014 (CHEMBL464006 | Morusin | Morusin, 3 | TCMDC-124149...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Veterinary and Pharmaceutical Sciences Brno Curated by ChEMBL | Assay Description Inhibition of 5-LOX | J Nat Prod 74: 614-9 (2011) Article DOI: 10.1021/np100638h BindingDB Entry DOI: 10.7270/Q2Z89CRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyunsaturated fatty acid lipoxygenase ALOX12 (Homo sapiens (Human)) | BDBM50242014 (CHEMBL464006 | Morusin | Morusin, 3 | TCMDC-124149...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Veterinary and Pharmaceutical Sciences Brno Curated by ChEMBL | Assay Description Inhibition of 12-LOX | J Nat Prod 74: 614-9 (2011) Article DOI: 10.1021/np100638h BindingDB Entry DOI: 10.7270/Q2Z89CRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50242014 (CHEMBL464006 | Morusin | Morusin, 3 | TCMDC-124149...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Veterinary and Pharmaceutical Sciences Brno Curated by ChEMBL | Assay Description Inhibition of ram seminal vesicle COX-1 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassay | J Nat Prod 74: 614-9 (2011) Article DOI: 10.1021/np100638h BindingDB Entry DOI: 10.7270/Q2Z89CRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
