Affinity Data by PubMed id=21349709

PubMed code 21349709

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50237601 (CHEMBL411941 \| CycloRGDfV \| [(2S,5R,8S,11S)-5-Benz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340881 (CHEMBL1761774 \| cyclo[Arg-Gly-Asp-D-Phe-Lys(epselo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340877 (CHEMBL1761773 \| Cypate-cyclo(Cys-Arg-Gly-Asp-Cys)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340880 (2-(7-(3-(3-((3S,6R,11R,14S,19aS)-6-carbamoyl-3-(ca...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340879 (2-(7-(3-(3-((4R,7S,10S,13S,16R)-4-carbamoyl-7-(car...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340878 (2-(7-(3-(3-((4R,7S,10S,13S,16R)-4-carbamoyl-7-(car...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%