Affinity Data by PubMed id=21353776

PubMed code 21353776

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50340957 (8-nitro-2-(2,3,4-trihydroxyphenyl)naphthalene-1,4-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of Aurora A				Bioorg Med Chem Lett 21: 2079-82 (2011) Article DOI: 10.1016/j.bmcl.2011.02.001 BindingDB Entry DOI: 10.7270/Q2ZW1M77
University of Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50340956 (5,8-dihydroxy-2-(2,3,4-trihydroxyphenyl)naphthalen...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of Aurora A				Bioorg Med Chem Lett 21: 2079-82 (2011) Article DOI: 10.1016/j.bmcl.2011.02.001 BindingDB Entry DOI: 10.7270/Q2ZW1M77
University of Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50340955 (2-(2,4-dihydroxyphenyl)-8-hydroxy-1,4-naphthoquino...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of Aurora A				Bioorg Med Chem Lett 21: 2079-82 (2011) Article DOI: 10.1016/j.bmcl.2011.02.001 BindingDB Entry DOI: 10.7270/Q2ZW1M77
University of Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50340955 (2-(2,4-dihydroxyphenyl)-8-hydroxy-1,4-naphthoquino...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of DYRK1a				Bioorg Med Chem Lett 21: 2079-82 (2011) Article DOI: 10.1016/j.bmcl.2011.02.001 BindingDB Entry DOI: 10.7270/Q2ZW1M77
University of Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50340956 (5,8-dihydroxy-2-(2,3,4-trihydroxyphenyl)naphthalen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of DYRK1a				Bioorg Med Chem Lett 21: 2079-82 (2011) Article DOI: 10.1016/j.bmcl.2011.02.001 BindingDB Entry DOI: 10.7270/Q2ZW1M77
University of Padova Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%