Affinity Data by PubMed id=21375347

PubMed code 21375347

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50341432 (1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione \|...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP2C9 in human liver microsomes				J Med Chem 54: 2409-21 (2011) Article DOI: 10.1021/jm101549k BindingDB Entry DOI: 10.7270/Q2VX0GT7
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50341432 (1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione \|...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes				J Med Chem 54: 2409-21 (2011) Article DOI: 10.1021/jm101549k BindingDB Entry DOI: 10.7270/Q2VX0GT7
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50341432 (1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione \|...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP2C19 in human liver microsomes				J Med Chem 54: 2409-21 (2011) Article DOI: 10.1021/jm101549k BindingDB Entry DOI: 10.7270/Q2VX0GT7
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50341432 (1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione \|...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes				J Med Chem 54: 2409-21 (2011) Article DOI: 10.1021/jm101549k BindingDB Entry DOI: 10.7270/Q2VX0GT7
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50341432 (1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione \|...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP1A2 in human liver microsomes				J Med Chem 54: 2409-21 (2011) Article DOI: 10.1021/jm101549k BindingDB Entry DOI: 10.7270/Q2VX0GT7
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%