Found 24 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Adenosine receptor A1
(Homo sapiens (Human)) | BDBM50340226
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-(oxazol...)Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)-c2ncco2)cn1 Show InChI InChI=1S/C16H14N6O2/c1-9-2-3-10(7-19-9)8-22-12-6-11(15-18-4-5-24-15)20-14(17)13(12)21-16(22)23/h2-7H,8H2,1H3,(H2,17,20)(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Adenosine receptor A1 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Homo sapiens (Human)) | BDBM50340223
(4-amino-6-(4-methyloxazol-2-yl)-1-((6-methylpyridi...)Show SMILES Cc1coc(n1)-c1cc2n(Cc3ccc(C)nc3)c(=O)[nH]c2c(N)n1 Show InChI InChI=1S/C17H16N6O2/c1-9-3-4-11(6-19-9)7-23-13-5-12(16-20-10(2)8-25-16)21-15(18)14(13)22-17(23)24/h3-6,8H,7H2,1-2H3,(H2,18,21)(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Adenosine receptor A1 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Homo sapiens (Human)) | BDBM50340221
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-(2H-1,2...)Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)-n2nccn2)cn1 Show InChI InChI=1S/C15H14N8O/c1-9-2-3-10(7-17-9)8-22-11-6-12(23-18-4-5-19-23)20-14(16)13(11)21-15(22)24/h2-7H,8H2,1H3,(H2,16,20)(H,21,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Adenosine receptor A1 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Homo sapiens (Human)) | BDBM50340230
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-(1H-pyr...)Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)-n2cccn2)cn1 Show InChI InChI=1S/C16H15N7O/c1-10-3-4-11(8-18-10)9-22-12-7-13(23-6-2-5-19-23)20-15(17)14(12)21-16(22)24/h2-8H,9H2,1H3,(H2,17,20)(H,21,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Adenosine receptor A1 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340237
(4-amino-6-((1-methylpiperidin-4-yl)methoxy)-1-((6-...)Show SMILES CN1CCC(COc2cc3n(Cc4ccc(C)nc4)c(=O)[nH]c3c(N)n2)CC1 Show InChI InChI=1S/C20H26N6O2/c1-13-3-4-15(10-22-13)11-26-16-9-17(23-19(21)18(16)24-20(26)27)28-12-14-5-7-25(2)8-6-14/h3-4,9-10,14H,5-8,11-12H2,1-2H3,(H2,21,23)(H,24,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340238
(4-amino-6-(3-methoxypropoxy)-1-((6-methylpyridin-3...)Show SMILES COCCCOc1cc2n(Cc3ccc(C)nc3)c(=O)[nH]c2c(N)n1 Show InChI InChI=1S/C17H21N5O3/c1-11-4-5-12(9-19-11)10-22-13-8-14(25-7-3-6-24-2)20-16(18)15(13)21-17(22)23/h4-5,8-9H,3,6-7,10H2,1-2H3,(H2,18,20)(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340220
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-(triflu...)Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)cn1 Show InChI InChI=1S/C14H12F3N5O/c1-7-2-3-8(5-19-7)6-22-9-4-10(14(15,16)17)20-12(18)11(9)21-13(22)23/h2-5H,6H2,1H3,(H2,18,20)(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340223
(4-amino-6-(4-methyloxazol-2-yl)-1-((6-methylpyridi...)Show SMILES Cc1coc(n1)-c1cc2n(Cc3ccc(C)nc3)c(=O)[nH]c2c(N)n1 Show InChI InChI=1S/C17H16N6O2/c1-9-3-4-11(6-19-9)7-23-13-5-12(16-20-10(2)8-25-16)21-15(18)14(13)22-17(23)24/h3-6,8H,7H2,1-2H3,(H2,18,21)(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 87 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340225
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-((tetra...)Show SMILES Cc1ccc(Cn2c3cc(OCC4CCOCC4)nc(N)c3[nH]c2=O)cn1 Show InChI InChI=1S/C19H23N5O3/c1-12-2-3-14(9-21-12)10-24-15-8-16(22-18(20)17(15)23-19(24)25)27-11-13-4-6-26-7-5-13/h2-3,8-9,13H,4-7,10-11H2,1H3,(H2,20,22)(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 99 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340228
(4-amino-1-((6-methylpyridazin-3-yl)methyl)-6-(trif...)Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)nn1 Show InChI InChI=1S/C13H11F3N6O/c1-6-2-3-7(21-20-6)5-22-8-4-9(13(14,15)16)18-11(17)10(8)19-12(22)23/h2-4H,5H2,1H3,(H2,17,18)(H,19,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 411 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340233
(4-amino-1-((2-methyloxazol-4-yl)methyl)-6-(trifluo...)Show InChI InChI=1S/C12H10F3N5O2/c1-5-17-6(4-22-5)3-20-7-2-8(12(13,14)15)18-10(16)9(7)19-11(20)21/h2,4H,3H2,1H3,(H2,16,18)(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 193 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340222
(4-amino-1-((2-methylthiazol-4-yl)methyl)-6-(triflu...)Show InChI InChI=1S/C12H10F3N5OS/c1-5-17-6(4-22-5)3-20-7-2-8(12(13,14)15)18-10(16)9(7)19-11(20)21/h2,4H,3H2,1H3,(H2,16,18)(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340224
(4-amino-1-((5-methylpyridin-2-yl)methyl)-6-(triflu...)Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)nc1 Show InChI InChI=1S/C14H12F3N5O/c1-7-2-3-8(19-5-7)6-22-9-4-10(14(15,16)17)20-12(18)11(9)21-13(22)23/h2-5H,6H2,1H3,(H2,18,20)(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 95 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340221
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-(2H-1,2...)Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)-n2nccn2)cn1 Show InChI InChI=1S/C15H14N8O/c1-9-2-3-10(7-17-9)8-22-11-6-12(23-18-4-5-19-23)20-14(16)13(11)21-15(22)24/h2-7H,8H2,1H3,(H2,16,20)(H,21,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 51 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340226
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-(oxazol...)Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)-c2ncco2)cn1 Show InChI InChI=1S/C16H14N6O2/c1-9-2-3-10(7-19-9)8-22-12-6-11(15-18-4-5-24-15)20-14(17)13(12)21-16(22)23/h2-7H,8H2,1H3,(H2,17,20)(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 102 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340229
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-((tetra...)Show SMILES Cc1ccc(Cn2c3cc(OCC4CCOC4)nc(N)c3[nH]c2=O)cn1 Show InChI InChI=1S/C18H21N5O3/c1-11-2-3-12(7-20-11)8-23-14-6-15(26-10-13-4-5-25-9-13)21-17(19)16(14)22-18(23)24/h2-3,6-7,13H,4-5,8-10H2,1H3,(H2,19,21)(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 474 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340235
(4-amino-1-((6-methylpyridin-2-yl)methyl)-6-(triflu...)Show SMILES Cc1cccc(Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)n1 Show InChI InChI=1S/C14H12F3N5O/c1-7-3-2-4-8(19-7)6-22-9-5-10(14(15,16)17)20-12(18)11(9)21-13(22)23/h2-5H,6H2,1H3,(H2,18,20)(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 328 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340232
(4-amino-1-((tetrahydro-2H-pyran-3-yl)methyl)-6-(tr...)Show InChI InChI=1S/C13H15F3N4O2/c14-13(15,16)9-4-8-10(11(17)18-9)19-12(21)20(8)5-7-2-1-3-22-6-7/h4,7H,1-3,5-6H2,(H2,17,18)(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340234
(4-amino-1-benzyl-6-(trifluoromethyl)-1H-imidazo[4,...)Show InChI InChI=1S/C14H11F3N4O/c15-14(16,17)10-6-9-11(12(18)19-10)20-13(22)21(9)7-8-4-2-1-3-5-8/h1-6H,7H2,(H2,18,19)(H,20,22) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 269 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340236
(4-amino-1-((5-methylpyrazin-2-yl)methyl)-6-(triflu...)Show SMILES Cc1cnc(Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)cn1 Show InChI InChI=1S/C13H11F3N6O/c1-6-3-19-7(4-18-6)5-22-8-2-9(13(14,15)16)20-11(17)10(8)21-12(22)23/h2-4H,5H2,1H3,(H2,17,20)(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 352 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340231
(4-amino-1-(3-methoxypropyl)-6-(trifluoromethyl)-1H...)Show InChI InChI=1S/C11H13F3N4O2/c1-20-4-2-3-18-6-5-7(11(12,13)14)16-9(15)8(6)17-10(18)19/h5H,2-4H2,1H3,(H2,15,16)(H,17,19) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 833 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340230
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-(1H-pyr...)Show SMILES Cc1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)-n2cccn2)cn1 Show InChI InChI=1S/C16H15N7O/c1-10-3-4-11(8-18-10)9-22-12-7-13(23-6-2-5-19-23)20-15(17)14(12)21-16(22)24/h2-8H,9H2,1H3,(H2,17,20)(H,21,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 633 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340239
(4-amino-1-((2-methylpyrimidin-5-yl)methyl)-6-(trif...)Show SMILES Cc1ncc(Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)cn1 Show InChI InChI=1S/C13H11F3N6O/c1-6-18-3-7(4-19-6)5-22-8-2-9(13(14,15)16)20-11(17)10(8)21-12(22)23/h2-4H,5H2,1H3,(H2,17,20)(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 366 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
Toll-like receptor 7
(Homo sapiens (Human)) | BDBM50340227
(4-amino-1-((5-methylisoxazol-3-yl)methyl)-6-(trifl...)Show InChI InChI=1S/C12H10F3N5O2/c1-5-2-6(19-22-5)4-20-7-3-8(12(13,14)15)17-10(16)9(7)18-11(20)21/h2-3H,4H2,1H3,(H2,16,17)(H,18,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 103 | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at Toll-like receptor 7 |
Bioorg Med Chem Lett 21: 2389-93 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C |
More data for this
Ligand-Target Pair | |
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